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As science continues its evolution, discoveries and technologies can act like a master key that open doors leading to novel advancements. Artificial intelligence is one such key, making innovations possible by solving complex problems, automating tasks and enabling research that would have been impossible, or very time-consuming, without it. Mohammad Hosseini But do we want to do research on all topics, and shall we try the AI master key on every door? To explore this question, let’s consider the use of AI by genomics experts as an example. In recent years, genomics experts have added unbelievable depth to what we know about the world and ourselves. For example, genetics researchers have revealed facts about when certain animals and plants were domesticated. In another example, researchers used DNA from 30,000-year-old permafrost to create fertile samples of a plant called narrow-leafed campion. Importantly, genetic engineering has facilitated extraordinary advances in the treatment of complicated conditions, such as sickle-cell anemia. Thanks to AI, we are witnessing a dramatic increase in the pace and scalability of genomic exploration. But given the risks and possible consequences of AI use in science, should we rush headlong into using AI in all kinds of projects? One relevant example is research on Neanderthals, our closest relatives, who lived about 40,000 years ago. Neanderthals have been studied for several years now through genetic investigation of their fossils and their DNA. Genetic engineering can potentially use ancient DNA and genome editing methods to re-create a Neanderthal or aspects of a Neanderthal’s genetics and physiology. To do this, scientists could start by figuring out the DNA sequence of a Neanderthal by comparing it with the DNA of modern humans, because they are closely related. Then, scientists could use the gene-editing tool known as CRISPR to swap out parts of human DNA with Neanderthal DNA. This process would require a lot of trial and error and might not succeed soon. But based on what we know about genetics, if something is possible, AI can help make it happen faster, cheaper and with less effort. Scientists are excited about these developments because they could facilitate new discoveries and open up many research opportunities in genetic research. With or without AI, research on Neanderthals will proceed. But the extraordinary power of AI could give the final push to these discoveries and facilitate this kind of resurrection. At that point, the scientific community must develop norms and guidelines about how to treat these resurrected beings with dispositions very similar to humans. We would need to carefully consider their rights and well-being almost in the same way as when humans are involved and not as research subjects or artifacts of scientific curiosity. These ethical issues are discussed in more detail in a new paper published in the journal Nature Machine Intelligence. A more holistic question to consider is: Should we prioritize the use of resource-intensive AI, researchers’ time and public funds to resurrect extinct beings? Or should we invest these resources into conserving species that are critically endangered today to prevent biodiversity from more degradation? Hosseini is an assistant professor in the Department of Preventive Medicine at Northwestern University’s Feinberg School of Medicine. He wrote this for The Chicago Tribune . Get opinion pieces, letters and editorials sent directly to your inbox weekly!PPP celebrates 57th Foundation Day with Festive cake cutting ceremony

Neal Maupay: Whenever I’m having a bad day I check Everton score and smileShort Interest in Achilles Therapeutics plc (NASDAQ:ACHL) Drops By 33.9%Game and Fish announces closure of North Dakota otter trapping season

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Seattle-based Dr. Javad Sajan, who crowed about his race to complete “all my trans surgeries before Trump tries to stop me” in a viral TikTok video last month is getting hit with an ad campaign accusing him of profiting off of more than 100 of the “life-altering surgeries” — including some conducted on children. Do No Harm, an advocacy group opposed to the performance of transgender surgeries on minors , launched a digital ad campaign largely centered in the Seattle area to spotlight the dozens of sex-reassignment surgeries Sajan has performed and intends to keep performing until President-elect Donald Trump enters office. “He brags about performing the best top surgeries for minors and is pushing to do as many of these irreversible surgeries as he possibly can all while reaching millions of viewers on social media with his own damaging propaganda,” the spot said. “This isn’t care. This is immoral,” the ad continued. “Doctors like this aren’t looking out for our children, they’re profiting off their backs. It’s time to stop the madness.” Sajan, a plastic surgeon who specializes in breast augmentation and rhinoplasty, maintains an active social media presence laced with humor about his breast enhancement work and frank talk about the operations he performs. Shortly after Trump’s election victory, Sajan cut a viral TikTok video depicting him gearing up for operations with the caption, “Doing all my trans surgeries before Trump tries to stop me.” Do No Harm, which runs a database tracking transgender surgeries on minors, alleged in its ad that Sajan has completed 120 gender-transition surgeries on minors. The group made those accusations based on an assessment of health insurance claims data shared with The Post. A lawyer for Sajan disputed that statistic, telling The Post that it is “in no way accurate,” but did not provide evidence. “Because of patient privacy laws (e.g. HIPAA), we are unable to provide you with specifics about individual patients that have received care,” his attorney Erin O’Leary explained. “However, we will say that the total number of minors that have received gender-affirming care is a small fraction of the number you quoted and no one under the age of 16 has been treated.” Sajan has actively advertised in states like Arizona, Florida, Texas and Utah, where transgender surgeries on minors have been restricted, encouraging them to come to his practice on the West Coast. The spot against Sajan highlighted how he has boasted about how he “performs the best top surgery for minors.” O’Leary defended Sajan’s performance of top surgery on minors, arguing it is “similar to breast reduction or augmentation surgeries offered to patients of all genders for comfort, athletics, or aesthetic reasons.” Do No Harm also cited a lawsuit from the Washington State Attorney General Bob Ferguson’s Office against Sajan that alleged he improperly stifled negative reviews. Earlier this year, a federal judge concluded that he “illegally prevented patients from posting negative reviews about the business,” per a press release . The judge pointed to “pre-service” non-disclosure agreements between 2017 and 2022, determining that they “violated a federal law that protects consumers’ rights to post truthful reviews about a business.” In July, the judge determined that his practice must pay $5 million as a result of the alleged manipulation of reviews. O’Leary acknowledged the judge’s ruling which was based on the Consumer Review Fairness Act, but emphasized that other accusations pertaining to that suit were not proven. “All other allegations were just that, allegations. Further, they were denied by the practice and resolved through a mutual, no-fault settlement with the Attorney General’s Office in which both sides dismissed their allegations against the other,” she told The Post. Transgender surgeries on minors have faced growing backlash and litigation. Earlier this month, the US Supreme Court heard oral arguments over a Tennessee law that largely banned those procedures on minors, which limited exceptions. Do No Harm has estimated that between 2019 and 2023, there were at least 13,994 minors who underwent sex change treatments, including 5,700 who underwent operations. During that same time period, 8,579 were given hormones and puberty blockers, according to the group.Offensively challenged in several early high school basketball games this season, Terre Haute South shot 52% from the field Thursday afternoon in the fifth game of the First Financial Classic at Terre Haute North. Shakamak, a team that had South coach Braydon Jefferson worried, shot 33%, the result being a 57-44 win for the Braves that was decided early. “This is a team can shoots well and can make tough shots,” he said after the game in referring to the Lakers. “This time the ball bounced our way.” South jumped quickly into leads of 11-2, 13-3 and 16-5, and that was pretty much it. Shakamak rallied within 16-11 on a basket by reserve Mason Young and four points by Linden Jenkins. But 3-pointers by Treva Branch-Lewis and Peyton Turner — after the Braves had been 1 for 18 from beyond the arc in their previous game — made it 22-11 early in the second quarter and the lead didn’t vary much the rest of the way. Which wasn’t exactly what Jefferson had had in mind either. “We got a little lackadaisical and wanted to think we could coast,” he said about his team’s performance later in the game. “I wasn’t happy with our attention to detail.” South’s best stretch came in the third quarter, when the Braves built a 19-point lead at 46-27. Shakamak’s last gasp was cutting the lead to 55-44, but it was too little, too late. “I felt like we followed our game plan pretty well,” coach Brodie Crowe of the Lakers said after the game. “We limited our turnovers [six for the game, none in the second half] and we did a pretty good job on the boards considering [South’s] size advantage [which was considerable] . . . but it’s disappointing to lose a game we felt was one we should have won, except for our shooting.” South had a three-man attack as Chris Herrin scored 17 points (including a 3-pointer of his own), Turner 16 and Branch-Lewis 15. Jaylen Wells had a game-high nine rebounds four blocked shots, and Brady Wilson had four assists, three of them early in the game.” Jenkins led all scorers with 22 points for Shakamak, while Jaden Johnson had eight. Jenkins and Madden Husband had seven rebounds each. “We have a lot of guys who shoot pretty well,” Crowe emphasized. “We belong here . . . I wasn’t disappointed with our effort.” “We have to keep believing, keep trusting the process,” Jefferson concluded. TERRE HAUTE SOUTH (57) — Herrin 7-8 2-4 17, Wells 2-6 0-2 4, Turner 6-13 1-2 16, Branch-Lewis 5-7 3-6 15, Wilson 1-3 0-0 2, Morgan 1-3 0-0 2, T.Lewis 0-1 0-0 0, Wilkinson 0-0 0-0 0, Boyce 0-0 0-0 0, M.Lewis 0-0 1-2 1, Chastain 0-1 0-0 0, Semmler 0-0 0-0 0, Snider 0-0 0-0 0. Totals 22-42 FG, 7-16 FT, 57 TP. SHAKAMAK (44) — Jenkins 7-11 6-6 22, Husband 1-10 0-0 2, Terrell 1-5 1-2 3, Jad.Johnson 2-11 3-4 8, Jal.Johnson 2-4 0-1 4, Young 1-2 1-2 3, Fiscus 0-1 0-0 0, Miller 1-2 0-0 2, Buell 0-0 0-0 0, Roberts 0-0 0-0 0, Snellenberger 0-0 0-0 0, Agee M0-0 0-0 0. Totals 15-46 FG, 11-15 FT, 44 TP. 3-point shooting — THS 6-16 (Turner 3-8, Branch-Lewis 2-4, Herrin 1-1, Morgan 0-1, Wilson 0-2), Shakamak 3-18 (Jenkins 2-4, Jad.Johnson 1-5, Terrell 0-1, Jal.Johnson 0-1, Young 0-1, Fiscus 0-1, Husband 0-5). Total fouls — THS 16, Shakamak 15. Fouled out — none. Turnovers — THS 13, Shakamak 6. Rebounds — THS 36 (Wells 9, Turner 5, Branch-Lewis 5, Herrin 4, T.Lewis 4, Boyce 4, Wilson, Morgan, M.Lewis, Team 2), Shakamak 28 (Jenkins 7, Husband 7, Terrell 3, Jal.Johnson 3, Fiscus 2, Miller 2, Young, Snellenberger, Team 2). Assists — THS 16 (Branch-Lewis 6, Wilson 4, Turner 2, Wells 2, Herrin, T.Lewis), Shakamak 9 (Jad.Johnson 4, Terrell 2, Fiscus 2, Jenkins). Steals — THS 3 (Herrin, Branch-Lewis, Wilson), Shakamak 5 (Terrell 2, Jenkins, Husband, Jad.Johnson). Blocks — THS 4 (Wells 4), Shakamak 0. Next — Terre Haute South (4-3) plays a winners’ bracket game at 7 p.m. Shakamak (3-5) plays at 4 p.m.NPP needs to get serious about industrialisation to avoid another crisis

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