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jili1111 WALTHAM, Mass. , Dec. 3, 2024 /PRNewswire/ -- Syndax Pharmaceuticals (Nasdaq: SNDX), a commercial-stage biopharmaceutical company developing an innovative pipeline of cancer therapies, today announced that on December 1, 2024 the Company granted inducement awards to purchase up to 23,900 shares of common stock to two new employees under the Company's 2023 Inducement Plan. The stock options will vest over four years, with 25% of the underlying shares vesting on the one-year anniversary of the vesting commencement date and 1/48th of the underlying shares vesting monthly thereafter over 36 months, subject to the employee's continued service relationship with Syndax through the applicable vesting dates. About Syndax Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company developing an innovative pipeline of cancer therapies. Highlights of the Company's pipeline include Revuforj ® (revumenib), an FDA-approved menin inhibitor, and NiktimvoTM (axatilimab-csfr), an FDA-approved monoclonal antibody that blocks the colony stimulating factor 1 (CSF-1) receptor. Fueled by our commitment to reimagining cancer care, Syndax is working to unlock the full potential of its pipeline and is conducting several clinical trials across the continuum of treatment. For more information, please visit www.syndax.com or follow the Company on X (formerly Twitter) and LinkedIn . Syndax Contact Sharon Klahre Syndax Pharmaceuticals, Inc. sklahre@syndax.com Tel 781.684.9827 View original content: https://www.prnewswire.com/news-releases/syndax-pharmaceuticals-reports-inducement-grants-under-nasdaq-listing-rule-5635c4-302316942.html SOURCE Syndax Pharmaceuticals, Inc.

A Historic Index Continues to Shine The Dow Jones Industrial Average, a stalwart of American financial markets, showcases more than just numbers—it’s a pulse on economic sentiment. As this legendary index steadily climbed 15% this year, two standout companies, Nvidia and Walmart, have captured investors’ imaginations with stellar performances. Nvidia: Riding the AI Wave Leading the charge is Nvidia, an AI-driven powerhouse that has transformed the semiconductor landscape since its 1993 inception. The company specializes in cutting-edge GPUs and SoCs that are revolutionizing industries. With a breathtaking market capitalization of $3.4 trillion, Nvidia’s stock has soared 175% this year alone. Its latest quarterly results showcase enviable revenue figures of $35.1 billion, far surpassing market expectations. Nvidia’s relentless innovation drives its growth, highlighted by the introduction of the Blackwell platform. Expected to revolutionize AI model efficiency and energy use, Blackwell sets the stage for a formidable future. Looking ahead, Nvidia’s robust roadmap includes advances like Rubin and continued dominance in the GPU sphere, where it commands over 80% market share. Walmart: Retail’s Resilient Force Founded in 1962, Walmart’s global footprint stretches across over 10,500 stores worldwide. This retail giant has capitalized on both physical and digital avenues, with stock prices climbing a remarkable 74.8% year-to-date. The third quarter of fiscal 2025 was a testament to Walmart’s unmatched resilience, with revenues hitting $169.6 billion, invigorated by a burgeoning advertising business. Walmart’s pursuit of digital advancements and AI integration is redefining retail efficiency. The company anticipates strong financial growth, further solidifying its position as a market leader across various segments. Analysts overwhelmingly endorse Walmart with a “Strong Buy” recommendation, anticipating continued prosperity. The Future of Dow Jones: Innovations, Insights, and Market Trends The Dow Jones Industrial Average remains a crucial barometer of economic health and momentum. This year’s robust 15% ascent highlights burgeoning investor interest, particularly in standout performers like Nvidia and Walmart. These companies aren’t just riding the wave; they’re shaping the future of their respective industries. Nvidia: Pioneering AI Innovation Nvidia’s unparalleled success in the stock market, with a staggering 175% increase this year, is not just a coincidence. This is a testament to its strategic investments in AI and semiconductor technology. The introduction of their groundbreaking platform, Blackwell, aims to transform AI model efficiency, addressing long-standing energy consumption challenges in the tech industry. Nvidia’s dominance is shown through its remarkable market capitalization of $3.4 trillion, a figure that underscores its pivotal role in shaping future technological landscapes. Nvidia’s portfolio is expanding with future-oriented projects like Rubin, keeping the company at the forefront of the GPU market. Given its strong foothold, capturing over 80% of the market, Nvidia is poised for substantial growth and innovation in AI applications. Trends indicate continued advancement in high-performance computing, signaling new opportunities and competition dynamics within the tech industry. Walmart: The Digital Transformation of Retail Walmart’s impressive stock performance this year, with a rise of 74.8%, underscores its effective blend of digital innovation with traditional retail. The company’s efforts in digital transformation, particularly through artificial intelligence integration, are redefining retail processes, enhancing customer experiences, and optimizing operational efficiency. Walmart’s strong performance, propelled by their burgeoning advertising business, has generated revenues of $169.6 billion in the third quarter of fiscal 2025, showcasing the successful diversification of its revenue streams. Analysts remain confident in Walmart’s growth, reflecting in a consistent “Strong Buy” recommendation. As Walmart continues to innovate, it exemplifies how traditional retail can thrive in a digital era. Future Insights and Market Trends As Nvidia and Walmart exemplify transformative progress, broader market trends emerge. Sustainability, energy efficiency, and digital transformation are themes that investors are increasingly prioritizing. Companies like Nvidia are pioneering energy-efficient technologies, a critical innovation in the context of rising global energy concerns. Meanwhile, retailers like Walmart focus on digital synergies to maintain relevance and compete against pure e-commerce players. The intersection of technology with traditional sectors will likely redefine market dynamics, offering new use cases and growth opportunities. Innovations aimed at enhancing energy efficiency and retail experience are set to influence market strategies significantly. Predicting market movements, investors will look for companies that blend innovation with robust market fundamentals. For more on market dynamics and business strategies, visit the main pages of Nvidia and Walmart . These insights offer a glimpse into the evolving nature of how companies must adapt to achieve sustained growth in shifting economic landscapes.

Tech Titans and Retail Giants! The Dow’s Dazzling Stars to Watch.NEW ORLEANS (AP) — A scruffy little fugitive is on the lam again in New Orleans, gaining fame as he outwits a tenacious band of citizens armed with night-vision binoculars, nets and a tranquilizer rifle. Scrim, a 17-pound mutt that's mostly terrier, has become a folk hero, inspiring tattoos, T-shirts and even a ballad as he eludes capture from the posse of volunteers. And like any antihero, Scrim has a backstory: Rescued from semi-feral life at a trailer park and adopted from a shelter, the dog broke loose in April and scurried around the city until he was cornered in October and brought to a new home. Weeks later, he'd had enough. Scrim leaped out of a second-story window, a desperate act recorded in a now-viral video. Since then, despite a stream of daily sightings, he's roamed free. The dog’s fans include Myra and Steve Foster, who wrote “Ode to Scrim” to the tune of Ricky Nelson’s 1961 hit, “I’m a Travelin’ Man.” “I'm a travelin' dog and I've made a lot of stops/All over this town...” Leading the recapture effort is Michelle Cheramie, a 55-year-old former information technology professional. She lost everything — home, car, possessions — in Hurricane Katrina in 2005, and in the aftermath, found her calling rescuing pets. “I was like, ‘This is what I should be doing,’” Cheramie said. “I was born to rescue.” She launched Zeus’ Rescues, a nonprofit shelter that now averages 600 cat and dog adoptions a year and offers free pet food to anyone who needs it. She helped Scrim find the home he first escaped from. It was Cheramie's window Scrim leaped from in November. She's resumed her relentless mission since then, posting flyers on telephone poles and logging social media updates on his reported whereabouts. She's invested thousands of dollars on wildlife cameras, thermal sensors and other gear. She took a course offered by the San Diego Zoo on the finer points of tranquilizing animals. And she's developed a network of volunteers — the kind of neighbors who are willing to grid-search a city at 3 a.m. “...And at every stop I own the heart, of at least one lovely ... " People like writer David W. Brown, who manages a crowd-sourced Google Map of all known Scrim sightings. He says the search has galvanized residents from all walks of life to come together. As they search for Scrim, they hand out supplies to people in need. “Being a member of the community is seeing problems and doing what you can to make life a little better for the people around here and the animals around you,” Brown said. And neighbors like Tammy Murray, who had to close her furniture store and lost her father to Parkinson's disease. This search, she says, got her mojo back. “Literally, for months, I’ve done nothing but hunt this dog,” said Murray, 53. “I feel like Wile E. Coyote on a daily basis with him.” Murray drives the Zeus' Rescues' van towards reported Scrim sightings. She also handles a tactical net launcher, which looks like an oversized flashlight and once misfired, shattering the van's window as Scrim sped away. After realizing Scrim had come to recognize the sound of the van's diesel engine, Murray switched to a Vespa scooter, for stealth. “...If you're ever in the 9th Ward stop and see/My cute little mini poodle ...” Near-misses have been tantalizing. The search party spotted Scrim napping beneath an elevated house, and wrapped construction netting around the perimeter, but an over-eager volunteer broke ranks and dashed forward, leaving an opening Scrim slipped through. Scrim's repeated escapades have prompted near-daily local media coverage and a devoted online following. Cheramie can relate. “We’re all running from something or to something. He's doing that too,” she said. Cheramie's team dreams of placing the pooch in a safe and loving environment. But a social media chorus growing under the hashtag #FreeScrim has other ideas — they say the runaway should be allowed a life of self-determination. The animal rescue volunteers consider that misguided. “The streets of New Orleans are not the place for a dog to be free,” Cheramie said. “It’s too dangerous.” "... and my Shar-Pei doll down in old Treme/Waits for my return ..." Scrim was a mess when Cheramie briefly recaptured him in October, with matted fur, missing teeth and a tattered ear. His trembling body was scraped and bruised, and punctured by multiple projectiles. A vet removed one, but decided against operating to take out a possible bullet. The dog initially appeared content indoors, sitting in Cheramie's lap or napping beside her bed. Then while she was out one day, Scrim chewed through a mesh screen, dropped 13 feet to the ground and squeezed through a gap in the fence, trotting away. Murray said Cheramie's four cats probably spooked him. “I wholeheartedly believe the gangster-ass cats were messing with him,” Murray said. Cheramie thinks they may have gotten territorial. Devastated but undeterred, the pair is reassessing where Scrim might fit best — maybe a secure animal sanctuary with big outdoor spaces where other dogs can keep him company. Somewhere, Murray says, “where he can just breathe and be.” Brook is a corps member for The Associated Press/Report for America Statehouse News Initiative. Report for America is a nonprofit national service program that places journalists in local newsrooms to report on undercovered issues. Follow Brook on the social platform X: @jack_brook96

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VANCOUVER — The search and rescue organization for Metro Vancouver's North Shore mountains is warning people to do their research after international visitors became stranded in two separate incidents while relying on hiking apps to plan their routes. North Shore Rescue was called in on Nov. 28 to rescue a man from Norway who the organization said "seriously underestimated the difficulty" of a route marked in an online hiking app. Rescuers were back on a nearby mountain three nights later for a "virtually identical" operation, the group said in a social media post. Allan McMordie with North Shore Rescue managed the Sunday night rescue of a man at Goat Ridge, a backcountry area behind Grouse Mountain. He said the man from France told rescuers he had not been expecting snow, despite two of the local ski hills opening with fresh powder last month. "All you had to do was look at the top of the mountains from Vancouver and know there's snow up there," he said in an interview. "To be in running shoes and not even expecting any snow was pretty naive." The man had set out on a marked route, then decided to make his way through very rough, steep terrain to a separate trail at significantly higher elevation. "This is rugged backcountry," McMordie said. "It's almost impassable." McMordie could not confirm which apps the hikers in both recent rescues were using, but said a lack of any marked route or trail reports is a good indication to stop and turn around, and in any case, trip planning should involve multiple sources of information. If the man from France had done any research, McMordie said he would have discovered the backcountry area where he was rescued is closed for the winter. In both recent cases, he said there were signs at each trailhead with maps showing trails and topography, along with reminders about key steps in trip planning, he said. Both men were lucky to have been able to make 911 calls, McMordie added, as service is patchy in the area and their phone batteries had nearly run out. Above all, he said hikers should tell someone else where they're going and when they expect to return, so that person can alert local authorities if necessary. "Absolutely nobody knew where this person was and what he was doing that day," McMordie said of the man from France. "If he had not been able to get that (911) call out, he would still be there." North Shore Rescue said the course taken by the man from Norway was "barely a trail" in the summer and "nothing whatsoever" in the winter, making for "full mountaineering conditions" at this time of year. He called for help after hiking for eight hours that left him "tired, soaked (and) hypothermic" as the sun was setting," it said. It's doubtful the man would have survived the night in the Mount Seymour backcountry if he hadn't been able to make the call, the rescue group added. The man had been staying in a short-term accommodation and had taken an Uber to the trailhead. Only his girlfriend in Norway knew where he was, and he was not wearing or carrying adequate gear for the conditions, McMordie said. Vancouver-based Stephen Hui, the author of several B.C. hiking guidebooks, said the rough, mountainous terrain steps away from urban Metro Vancouver and the extent of the snowpack in winter is a surprise for many visiting hikers. Hui said online apps can be helpful and often provide commentary about trail conditions from other hikers, but it's crucial to look at additional sources of information, including complete maps and provincial and national park websites. He said local authorities and outdoor groups have some responsibility for people heading into the backcountry, and there is room for more signage and education. Ultimately, though, he said people must be responsible for themselves. "We can't handhold everybody," he said. "There's always going to be dangers in hiking." This report by The Canadian Press was first published Dec. 5, 2024. Brenna Owen, The Canadian PressChargers RB J.K. Dobbins unlikely to play against Falcons because of knee injuryAP Sports SummaryBrief at 6:49 p.m. EST

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Tech to drive India's manufacturers growth: SurveyDressed in a black sweatshirt and tie-dyed leggings, Hannah Kobayashi casually walked off her flight from Maui to Los Angeles International Airport on November 8. The 30-year-old had plans to fly to New York City the same day. But she did not board that plane. Then, she seemingly vanished. Described by those who love her as an artistic and creative soul , the Hawaii native’s sudden disappearance has captivated the media as photos of her beaming smile and flowing locks of dark hair have blanketed television screens across the United States. Adding to her family’s anguish, Kobayashi’s father took his own life a few days before Thanksgiving after he had traveled to Los Angeles to search for her, according to the Los Angeles County medical examiner’s office. For nearly a month the Los Angeles Police Department, along with family, friends and volunteers, searched for Kobayashi. But this week, she was declared a voluntary missing person after police say she traveled to the US-Mexico border and crossed into Mexico on November 12. “We reviewed video surveillance from US Customs and Border Protection which clearly shows Kobayashi crossing United States border on foot into Mexico,” Los Angeles Police Chief Jim McDonnell said Monday in a news conference. “She was alone, with her luggage, and appeared unharmed.” Before leaving Maui, Kobayashi had expressed a desire to disconnect from modern technology, McDonnell added. Many people who go missing leave of their own accord for personal reasons, officials say. Last month, a Wisconsin kayaker was reported missing and is now accused of faking his own drowning and fleeing the country, authorities say. In 2023, over 563,000 people were reported missing in the United States, according to the Federal Bureau of Investigation’s Crime Information Center. The largest subgroup of missing persons – 125,390 – includes those who may have left voluntarily, the center’s data shows. Others include missing minors, kidnapping victims and disabled people who have wandered off, according to the FBI. Deciding how to proceed with searching for a missing person varies case to case, and sometimes race and news coverage play a role. “People are allowed to come and go as they please,” said Derrica Wilson, co-founder of Black & Missing Foundation , a non-profit that brings awareness to missing persons of color. However, Wilson – a former police officer – said law enforcement works for the community, and it is their responsibility to help loved ones search for a missing person, regardless of the situation surrounding their disappearance and despite race, gender and ZIP code. Missing persons standard procedures For every person that goes missing voluntarily, there are countless others who had no say in their disappearance, according to the International Association of Chiefs of Police, which has developed a missing persons policy for law enforcement agencies to abide by when working on a missing persons case. Reporting a missing person: There is no waiting period for loved ones to report a person missing, either in person or over the phone. At this point, police consider how “critical” the situation is. Who is a “missing” person: A person is often declared missing when their loved ones do not know their whereabouts and cannot explain why they can’t be found. Oftentimes the missing person’s unknown location is odd or unusual to their loved ones. When someone is critically missing: An individual is considered “missing-critical” when they are believed to be the subject of foul play, a minor, mentally disabled, suicidal or the victim of an accident. The preliminary investigation: Investigators focus on getting a description and photo of the person, determining if the person has any physical or emotional problems, and identifying the last individual who saw the person. They try to establish the “plans, habits, routines and personal interests of the subject including places frequented or locations of particular personal significance,” according to the policy. And they look out for “indications of missing personal belongings, particularly money and other valuables,” the policy says. Each state handles missing persons reports differently, Wilson added, and each law enforcement agency within those states has its own process for investigating cases. “There is no holistic approach when it comes to law enforcement response to missing person cases,” Wilson said. “In some states, law enforcement require families to wait 24 hours before reporting their loved ones missing.” Other states have laws prohibiting a wait period, she said. Kobayashi fit the criteria for a missing person considering the unusual circumstances in which she disappeared and concern from her family and friends, according to Wilson. “When you have a family that’s coming to you and they’re saying, ‘My loved one is missing, I have no idea where my loved one is. This is out of character. This is unusual,’ you want (law enforcement) to have empathy and sympathy. You want them to do their job,” Wilson told CNN Tuesday. Meanwhile, officials say they now have reason to believe Kobayashi is safe. “To date the investigation has not uncovered any evidence that Kobayashi is being trafficked or is the victim of foul play. She is also not a suspect in any criminal activity,” McDonnell said. “She has a right to her privacy, and we respect her choices but we also understand that the concern her loved ones feel for her.” Kobayashi’s family said in a statement Tuesday they are grateful for the “urgency and dedication” from law enforcement and remain “hopeful” that she is safe and urged the public to keep searching for her. “We want answers and a resolution that ensures Hannah’s safety and urge law enforcement and the public to stay focused on finding her and to avoid speculative conclusions,” the statement said. The media and race play a role In recent years, the families of missing people of color and LGBTQ+ individuals have blamed the news media for disproportionately covering cases of young, attractive missing White women, like 22-year-old travel blogger Gabby Petito , whose 2021 murder by her boyfriend Brian Laundrie took audiences by storm. News coverage of a missing person can help locate them, Wilson notes. “It alerts the community that someone is missing, number one, and then number two, it provides pressure to law enforcement to dedicate more resources.” While Kobayashi is not White, Wilson said, her attractiveness and public persona played a role in her case blowing up online. Black families say they often struggle to get the police to take their missing person cases seriously. Officers are slow to investigate their loved one’s disappearance or immediately label them as a “runaway,” they say. Black families say they often struggle to get the police to take their missing person cases seriously. Officers are slow to investigate their loved one’s disappearance or immediately label them as a “runaway,” they say. Wilson recalls a phone call she got from the mother of a young missing Black woman who watched the constant media coverage of Petito’s disappearance. “The mother asked me, ‘Why is my daughter any different?’” Wilson said. Wilson currently has nearly 6,000 cases of missing Black people in her database, most unsolved. Many disappearances in the Black community stem from human trafficking, domestic violence and mental health incidents, Wilson previously told CNN. It’s often an “uphill battle” to get the cases of missing Black people amplified and she wants the public to continue sounding the alarm, Wilson said. “We want people to continue making these cases viral,” Wilson said. “We can’t allow this case to diminish our efforts that we have worked so hard for.” CNN’s Michelle Watson, Caroll Alvarado, Artemis Moshtaghian, Karina Tsui and Nicquel Terry Ellis contributed to this report.

Dow Jones futures edged lower after hours, along with S&P 500 futures and Nasdaq futures with the November jobs report on tap. ( ), ( ) and ( ) were among the notable earnings reports Thursday night. The stock market rally saw modest losses Thursday after the S&P 500 and Nasdaq hit fresh all-time highs intraday. Small caps extended a pullback. Bitcoin topped $100,000 for the first time, but couldn't hold that level. It kept falling in late trading. Many crypto plays erased intraday gains, including ( ) and ( ) ( ) cleared short-term highs, offering fresh early entries. ( ) ( ), ( ) and ( ) were among stocks flashing buy signals. ( ) moved above a trading range to a new two-year high. A number of highly extended stocks became more so. Investors need a game plan for handling these "heat" stocks. Tesla stock is on the watchlist. Samsara stock is on the . Microsoft stock is on BlackRock was Thursday's . Confluent stock was Wednesday's pick. Dow Jones Futures Today Dow Jones futures edged lower vs. fair value. S&P 500 futures lost a fraction and Nasdaq 100 futures dipped 0.1%. Remember that overnight action in and elsewhere doesn't necessarily translate into actual trading in the next regular session. Bitcoin Bitcoin rose 0.2% to $99,137.34 as of 4 p.m. ET vs. 24 hours earlier. But the cryptocurrency came off early Thursday highs of $103,900 after topping the $100,000 level for the first time Wednesday night. It didn't stop there. Bitcoin slumped Thursday night to around $96,500 after briefly spiking down to $92,111. MicroStrategy stock, which jumped to 444.94 soon after the open, reversed to close down 4.8% to 386.40. MSTR stock is off 0.3% for the week but up nearly 513% so far in 2024. Coinbase stock backed off a record high of 349.49 to finish down 3.1% to 320.57. But COIN stock is up 8.2% for the week and 84% in 2024. Jobs Report The Labor Department will report the November jobs report at 8:30 a.m. ET. Economists expect nonfarm payrolls to rise by 200,000 after job growth cooled to just 12,000 in October due to hurricanes and strikes. That included a loss of 28,000 private jobs. The jobless rate should tick up to 4.2%, while the annual gain in average hourly earnings should edge down to 3.9%. Earnings Software makers DocuSign, GitLab, Samsara, ( ), ( ), Microsoft-backed cybersecurity IPO ( ) and ( ) reported Thursday night, along with ( ) and retailers ( ), ( ) and ( ). Rubrik, Asana, DocuSign, Ulta Beauty, Lululemon and GitLab stock were big winners overnight, with Veeva up as well. and UiPath tumbled. HPE and Victoria's Secret wavered around break-even. HP Enterprise had moved into a buy zone Thursday on an analyst upgrade just before earnings. Veeva stock also closed in a buy zone. GitLab closed modestly below a buy point. PATH stock was slightly extended from a bottoming base, but hitting resistance at the 200-day line. The other stocks were either extended from buy zones or lagging for months. Stock Market Rally The stock market rally faded into the close Thursday, but near record highs. The Dow Jones Industrial Average declined 0.55% in Thursday's . The S&P 500 index and Nasdaq composite retreated 0.2%. The small-cap Russell 2000 fell 1.25%. Leading stocks are generally faring well, with speculative stocks really coming on. Airline stocks jumped on bullish guidance from ( ) and ( ) However, after several big earnings winners on Wednesday, several software plays tumbled on results Thursday. Homebuilders continue to struggle, even with Treasury yields holding at their lowest levels in weeks. U.S. crude oil prices fell 0.35% to $68.30 a barrel. The 10-year Treasury yield was flat at 4.18%, again backing off morning highs. ETFs Among growth ETFs, the Innovator IBD 50 ETF ( ) dipped 0.2%. The iShares Expanded Tech-Software Sector ETF ( ) gave up 1.2%. Microsoft stock is a big component, with Samsara, GitLab, UiPath, Asana and DocuSign stock also in IGV. The VanEck Vectors Semiconductor ETF ( ) sank 1.7%, with Nvidia the dominant holding. ARK Innovation ETF ( ) declined 0.7% and ARK Genomics ETF ( ) slumped 3.6%. Tesla stock remains a major component across Ark Invest's ETFs. Cathie Wood also has built up a sizable stake in NVDA stock. SPDR S&P Metals & Mining ETF ( ) shed 0.7%. U.S. Global Jets ETF ( ) ascended 3.1%, with American Airlines and Southwest both big components. SPDR S&P Homebuilders ETF ( ) stepped down 1.5%. The Energy Select SPDR ETF ( ) rose 0.4%. The Health Care Select Sector SPDR Fund ( ) fell 1.1% and the Industrial Select Sector SPDR Fund ( ) lost 1.2%. The Financial Select SPDR ETF ( ) climbed 0.3%. Tesla Stock Tesla stock popped 3.2% to 369.49 on Thursday, clearing a recent range to hit a fresh two-year high. That could have offered an add-on entry for existing TSLA holders, but shares are significantly extended from key moving averages. On Thursday, Bank of America raised its TSLA price target to 400 from 350 in a highly bullish note. BofA is fully expecting Tesla robotaxis and the Optimus robot in the near future. What To Do Now The market rally had a relatively quiet day at or around record highs. "Heat" has definitely been working, with more speculative names running especially hot. If you own greatly extended stocks, a key question is when to sell. When stocks are more than 20%-30% above their 10-day moving averages, 100% over their 50-day lines or 200% above the 200-day, it may be prudent to bank some profits. A lot will depend on your conviction in the stock and your investing style. Some people are looking to hold for the big run, while others want to cash in. If you're going for home runs, you have to accept major drawdowns, with the risk that you'll eventually cut bait after giving up much of your gains. It doesn't have to be an all-or-nothing. Investors can take partial profits on the way up. That can give you the confidence to hold the remaining core position — and to be more willing to sell the remainder if the stock breaks hard. On the way down, investors can take profits on a major point loss or drop through the 10-day line, with other lines in the sand to draw you out. The key is to find a strategy that works for you. So have an exit strategy for those winners. Read every day to stay in sync with the market direction and leading stocks and sectors.Israeli hospital says Netanyahu has undergone successful prostate surgery

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Stocks making the biggest moves after hours: General Motors, Dave & Buster's, GE Vernova and more - CNBCRashmi is a Special Correspondent with The Times of India in Chhattisgarh. She covers Politics, Left Wing Extremism, Crime and Human Rights among other areas of news value. How to make healthy Oats Palak Chilla for a kid's tiffin 10 best Fried Chicken dishes from around the world 10 ways to use turmeric in winters ​10 animals not allowed as pets in India​ 10 types of Dosa and how they are made Animals and their favourite foods 9 nuts to eat daily for hair growth in winters How to make South Indian Podi Dosa at home From tigers to cheetahs: India’s big cats and where to find them Weekend Special: How to make Multigrain Thaalipeeth