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By MICHELLE L. PRICE and ROB GILLIES NEW YORK (AP) — President-elect Donald Trump’s recent dinner with Canadian Prime Minister Justin Trudeau and his visit to Paris for the reopening of the Notre Dame Cathedral were not just exercises in policy and diplomacy. They were also prime trolling opportunities for Trump. Related Articles National Politics | Biden issues veto threat on bill expanding federal judiciary as partisan split emerges National Politics | Trump lawyers and aide hit with 10 additional felony charges in Wisconsin over 2020 fake electors National Politics | After withdrawing as attorney general nominee, Matt Gaetz lands a talk show on OANN television National Politics | What will happen to Social Security under Trump’s tax plan? National Politics | Republican-led states are rolling out plans that could aid Trump’s mass deportation effort Throughout his first term in the White House and during his campaign to return, Trump has spun out countless provocative, antagonizing and mocking statements. There were his belittling nicknames for political opponents, his impressions of other political figures and the plentiful memes he shared on social media. Now that’s he’s preparing to return to the Oval Office, Trump is back at it, and his trolling is attracting more attention — and eyerolls. On Sunday, Trump turned a photo of himself seated near a smiling first lady Jill Biden at the Notre Dame ceremony into a social media promo for his new perfume and cologne line, with the tag line, “A fragrance your enemies can’t resist!” The first lady’s office declined to comment. When Trudeau hastily flew to Florida to meet with Trump last month over the president-elect’s threat to impose a 25% tax on all Canadian products entering the U.S., the Republican tossed out the idea that Canada become the 51st U.S. state. The Canadians passed off the comment as a joke, but Trump has continued to play up the dig, including in a post Tuesday morning on his social media network referring to the prime minister as “Governor Justin Trudeau of the Great State of Canada.” After decades as an entertainer and tabloid fixture, Trump has a flair for the provocative that is aimed at attracting attention and, in his most recent incarnation as a politician, mobilizing fans. He has long relished poking at his opponents, both to demean and minimize them and to delight supporters who share his irreverent comments and posts widely online and cheer for them in person. Trump, to the joy of his fans, first publicly needled Canada on his social media network a week ago when he posted an AI-generated image that showed him standing on a mountain with a Canadian flag next to him and the caption “Oh Canada!” After his latest post, Canadian Immigration Minister Marc Miller said Tuesday: “It sounds like we’re living in a episode of South Park.” Trudeau said earlier this week that when it comes to Trump, “his approach will often be to challenge people, to destabilize a negotiating partner, to offer uncertainty and even sometimes a bit of chaos into the well established hallways of democracies and institutions and one of the most important things for us to do is not to freak out, not to panic.” Even Thanksgiving dinner isn’t a trolling-free zone for Trump’s adversaries. On Thanksgiving Day, Trump posted a movie clip from “National Lampoon’s Christmas Vacation” with President Joe Biden and other Democrats’ faces superimposed on the characters in a spoof of the turkey-carving scene. The video shows Trump appearing to explode out of the turkey in a swirl of purple sparks, with the former president stiffly dancing to one of his favorite songs, Village People’s “Y.M.C.A.” In his most recent presidential campaign, Trump mocked Florida Gov. Ron DeSantis, refusing to call his GOP primary opponent by his real name and instead dubbing him “Ron DeSanctimonious.” He added, for good measure, in a post on his Truth Social network: “I will never call Ron DeSanctimonious ‘Meatball’ Ron, as the Fake News is insisting I will.” As he campaigned against Biden, Trump taunted him in online posts and with comments and impressions at his rallies, deriding the president over his intellect, his walk, his golf game and even his beach body. After Vice President Kamala Harris took over Biden’s spot as the Democratic nominee, Trump repeatedly suggested she never worked at McDonalds while in college. Trump, true to form, turned his mocking into a spectacle by appearing at a Pennsylvania McDonalds in October, when he manned the fries station and held an impromptu news conference from the restaurant drive-thru. Trump’s team thinks people should get a sense of humor. “President Trump is a master at messaging and he’s always relatable to the average person, whereas many media members take themselves too seriously and have no concept of anything else other than suffering from Trump Derangement Syndrome,” said Steven Cheung, Trump’s communications director. “President Trump will Make America Great Again and we are getting back to a sense of optimism after a tumultuous four years.” Though both the Biden and Harris campaigns created and shared memes and launched other stunts to respond to Trump’s taunts, so far America’s neighbors to the north are not taking the bait. “I don’t think we should necessarily look on Truth Social for public policy,” Miller said. Gerald Butts, a former top adviser to Trudeau and a close friend, said Trump brought up the 51st state line to Trudeau repeatedly during Trump’s first term in office. “Oh God,” Butts said Tuesday, “At least a half dozen times.” “This is who he is and what he does. He’s trying to destabilize everybody and make people anxious,” Butts said. “He’s trying to get people on the defensive and anxious and therefore willing to do things they wouldn’t otherwise entertain if they had their wits about them. I don’t know why anybody is surprised by it.” Gillies reported from Toronto. Associated Press writer Darlene Superville contributed to this report.
The Detroit Lions are facing a Chicago Bears team that are coming off of another tough loss. Related Articles Detroit Lions | Grading the Lions’ Week 12 win, as the defense smothers the Colts Detroit Lions | Lions rush for 3 scores and use stingy defense to beat Colts 24-6 for 9th straight win Detroit Lions | Takeaways as Lions cruise past Colts, 24-6, despite injuries piling up Detroit Lions | Photo gallery from the Lions’ 24-6 road win over the Colts Detroit Lions | Lions place Ennis Rakestraw on IR, activate Emmanuel Moseley Despite tying the game late, the Bears went on to lose to the Vikings in overtime, 30-27, dropping their fifth consecutive game and dipping their record to 4-7. For Dan Campbell’s squad, three key contributors may not be available, especially with the upcoming game occurring just four days after a 24-6 win against the Indianapolis Colts. Detroit’s fourth-year head coach expressed, “It’s going to come down to the wire with a number of them. That’s the challenge with the short week. The good news is, I think most of these are not some long-term thing, but the problem is three days to turn around and play. That’s where it becomes a bit of an issue. So, if we can’t, we’re prepare like we always are. Next man up. You got to hold the line, do your job and go compete.” When asked specifically about which three players are the toughest to decide upon, Campbell noted three key players who have helped the team win nine consecutive games may not suit up. “Right now, I mean, Decker, CD (Carlton Davis), Leaf (Kalif Raymond). Saint’s (Amon-Ra St. Brown) a little banged up. We’ll see how he recovers.” For the Lions, the message this week is about healing up and preparing mentally for another NFC North matchup. Detroit has not won on Thanksgiving since back in 2016. Quarterback Jared Goff expressed postgame the seven-game losing streak is one the current team would like to end. “Message is really recovery. Rest, recovery and the mental work,” said Campbell. “It’s how fast can you recover, get your body right, get your mind focused on the job at hand, because you’re not going to get the physical. Block out all the distractions. That’s one thing, the distractions are on us, not on them. We got all our family here, friends, all that. You got to block it out, tell them you love them, and you’ll see them him after the game. “That’s kind of the challenge with all this,” Campbell continued. “This team’s been in, they’ve lost a couple of heartbreakers in the last two weeks. But they’ve been in a bunch of these tight races, and they just keep coming back for more. So they’re hungry for a win. We got our hands full.” This article was produced by the staff at Detroit Lions On SI. For more, visit si.com/nfl/lionsThe Boeing 747's Longest Nonstop Passenger Flights In DecemberBOSTON (AP) — JB Frankel hit three of four free throws in the final six seconds to allow Northeastern to hold off Colgate 78-75 on Sunday. Nicolas Louis-Jacques hit three free throws for the Raiders with :07 left to get within two, 75-73, but Frankel hit the second of two to make it a three-point game and, after Jalen Cox hit a pair at the line to pull Colgate within one, 76-75, Frankel hit both free throws to seal the win. Rashad King had 23 points and added eight rebounds for the Huskies (7-3). Harold Woods scored 13 points and added six rebounds. Masai Troutman shot 2 of 7 from the field and 7 of 9 from the free-throw line to finish with 12 points. Brady Cummins led the way for the Raiders (2-8) with 15 points. Colgate also got 14 points, six rebounds, five assists and four steals from Jalen Cox. Louis-Jacques finished with 14 points. King scored 10 points in the first half and Northeastern went into the break trailing 32-28. Northeastern pulled off the victory after a 15-2 second-half run erased a three-point deficit and gave them the lead at 62-52 with 5:58 remaining in the half. King scored 13 second-half points. Northeastern takes on Old Dominion on the road on Sunday, and Colgate visits Kentucky on Wednesday. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .
A multi-billion-dollar infrastructure project is being planned to establish new transport links between Europe and West Asia . The proposed route will span across Iraq , stretching 745 miles from the northern Turkish border to the southern Persian Gulf. This mega-project, encompassing a network of roads, railways, ports and cities, aims to reduce travel time between Asia and Europe - posing competition to Egypt 's Suez Canal, a crucial trade route between the two continents. After establishing a trade corridor into Turkey , the project is expected to extend into Europe, bolstering Iraq 's global standing as well as its domestic economy and infrastructure, reports the Express . Inside the $20trillion Transatlantic Tunnel that would connect US to the UK in 54 minutes Man accused of shipping weapons to North Korea in shipping containers from US port The new route will build on the ongoing Grand Al Faw Port project - a port on the Persian Gulf that enables Iraq to better distribute its exports worldwide, marking the country's largest developmental endeavour so far. Iraqi Prime Minister Mohamed Shia al-Sudani views the project as a cornerstone of a sustainable non-oil economy, a link benefiting Iraq and the region, and a contribution to economic integration efforts," according to The Cradle . The project could be completed within three years. The ultimate goal is to establish an "uninterrupted highway and rail corridor between Basra and London ". The project could potentially surpass its stated cost of $17 billion. The Route of Development might present a more financially viable alternative to the Suez Canal, given the projected capacity of Grand Faw Port. DAILY NEWSLETTER: Sign up here to get the latest news and updates from the Mirror US straight to your inbox with our FREE newsletter. As reported by Anadolu Agency, the Iraqi Transport Minister said the port "will be able to host large trade ships with a depth of up to 19.5 metres". He also suggested it could save between 12 and 15 days in travel time compared to its Egypt -based counterpart. The project has received support from several influential states, with UAE and Qatar governments signing a memorandum last summer. However, Transport Minister Razzaq Muhibis Al-Saadawi emphasised that it's "a purely economy-focused project, completely devoid of politics". Speaking to AA, he said: "We will not engage in competition with any other party. " Iraq and Turkey have geographical advantages. We will utilize this for the benefit of our peoples." All the latest news, showbiz, lifestyle and sports updates, brought to you by our dedicated American team. Follow the Mirror US News page on Facebook to make sure you're not missing out.
MAHWAH, N.J.--(BUSINESS WIRE)--Nov 25, 2024-- KORU Medical Systems (NASDAQ: KRMD) (“KORU Medical” or the “Company”), a leading medical technology company focused on the development, manufacturing, and commercialization of innovative and patient-centric large volume subcutaneous infusion solutions, today announced that the Company will participate in Piper Sandler’s 36 th Annual Healthcare Conference on December 5, 2024. KORU Medical's management is scheduled to present at Piper Sandler’s 36 th Annual Healthcare Conference on December 5, 2024, at 11:00 am ET. Interested parties can access the live and archived webcast on the News/Events page of the Investors section of KORU Medical’s website at www.korumedical.com . About KORU Medical Systems KORU Medical develops, manufactures, and commercializes innovative and patient-centric large volume subcutaneous infusion solutions that improve quality of life for patients around the world. The FREEDOM Syringe Infusion System (“the FREEDOM System”) currently includes the FREEDOM60 ® and FreedomEdge ® Syringe Infusion Drivers, Precision Flow Rate TubingTM and HIgH-Flo Subcutaneous Safety Needle SetsTM. The Freedom System, which received its first FDA clearance in 1994, is used for self-administration in the home by the patient and/or delivery in an ambulatory infusion center by a healthcare professional. Through its Novel Therapies business, KORU Medical provides products for use by biopharmaceutical companies in feasibility/clinical trials during the drug development process and, as needed, is capable of customizing the Freedom System for clinical and commercial use across multiple drug categories. For more information, please visit www.korumedical.com . View source version on businesswire.com : https://www.businesswire.com/news/home/20241125412289/en/ CONTACT: Investor Contact: Greg Chodaczek 347-620-7010 investor@korumedical.com KEYWORD: NEW JERSEY UNITED STATES NORTH AMERICA INDUSTRY KEYWORD: MEDICAL DEVICES HEALTH CLINICAL TRIALS HEALTH TECHNOLOGY MEDICAL SUPPLIES SOURCE: KORU Medical Systems Copyright Business Wire 2024. PUB: 11/25/2024 04:05 PM/DISC: 11/25/2024 04:05 PM http://www.businesswire.com/news/home/20241125412289/en(All times Eastern) Schedule subject to change and/or blackouts Saturday, Nov. 23 AUSTRALIAN RULES FOOTBALL (WOMEN’S) 3:30 a.m. FS2 — AFL Playoffs: Adelaide at Brisbane, Preliminary Final AUTO RACING 12:55 a.m. (Sunday) ESPN — Formula 1: The Heineken Silver Las Vegas Grand Prix, Las Vegas Strip Circuit, Las Vegas COLLEGE BASKETBALL (MEN’S) Noon FS2 — St. Francis (Pa.) at Georgetown 5 p.m. FS2 — N. Illinois at DePaul COLLEGE BASKETBALL (WOMEN’S) 4 p.m. NBC — Notre Dame at Southern Cal PEACOCK — Notre Dame at Southern Cal COLLEGE CROSS COUNTRY (MEN’S and WOMEN’S) 9:30 a.m. ESPNU — NCAA Championships: From Verona, Wis. COLLEGE FOOTBALL Noon ABC — Mississippi at Florida ACCN — UConn at Syracuse BTN — Iowa at Maryland CBSSN — Sam Houston St. at Jacksonville St. CW — North Carolina at Boston College ESPN — Wake Forest at Miami ESPN2 — SMU at Virginia ESPNU — Yale at Harvard FOX — Indiana at Ohio St. PEACOCK — Illinois at Rutgers 12:45 p.m. SECN — UMass at Georgia 3:30 p.m. ABC — Kentucky at Texas ACCN — Stanford at California BTN — Wisconsin at Nebraska CBS — Penn St. at Minnesota CBSSN — San Diego St. at Utah St. CW — The Citadel at Clemson ESPN — BYU at Arizona St. ESPNU — UCF at West Virginia FOX — Colorado at Kansas FS1 — Northwestern at Michigan 4 p.m. ESPN2 — Pittsburgh at Louisville 4:15 p.m. SECN — Missouri at Mississippi St. 7 p.m. CBSSN — Boise St. at Wyoming CW — Washington St. at Oregon St. FS1 — Baylor at Houston NBC — Army vs. Notre Dame, New York PEACOCK — Army vs. Notre Dame, New York 7:30 p.m. ABC — Alabama at Oklahoma ESPN — Texas A&M at Auburn ESPNU — Marshall at Old Dominion FOX — Iowa St. at Utah 7:45 p.m. SECN — Vanderbilt at LSU 8 p.m. ACCN — Virginia Tech at Duke ESPN2 — Cincinnati at Kansas St. 10:15 p.m. NBC — Southern Cal at UCLA 10:30 p.m. CBSSN — Colorado St. at Fresno St. FS1 — Air Force at Nevada 11 p.m. ESPNU — Florida A&M at Bethune-Cookman (Taped) COLLEGE VOLLEYBALL (WOMEN’S) 8 p.m. BTN — Wisconsin at Nebraska GOLF 1 p.m. GOLF — PGA Tour: The RSM Classic, Third Round, Sea Island Golf Club - Seaside Course, Sea Island, Ga. 4 p.m. GOLF — LPGA Tour: The CME Group Tour Championship, Third Round, Tiburon Golf Club, Naples, Fla. (Taped) 9:30 p.m. GOLF — DP World Tour: The BMW Australian PGA Championship, Final Round, Royal Queensland Golf Club, Brisbane, Australia 1 a.m. (Saturday) GOLF — Asian Tour: The LINK Hong Kong Open, Final Round, Hong Kong Golf Club, Hong Kong HORSE RACING 11:30 a.m. FS1 — NYRA: America’s Day at the Races 3:30 p.m. FS2 — NYRA: America’s Day at the Races 1 a.m. (Sunday) FS2 — The Japan Cup: From Tokyo Racecourse, Tokyo NBA BASKETBALL 5 p.m. NBATV — New York at Utah 8 p.m. NBATV — Memphis at Chicago 10:30 p.m. NBATV — Denver at L.A. Lakers NHL HOCKEY 1 p.m. NHLN — Chicago at Philadelphia 7 p.m. NHLN — Vegas at Montreal SAILING 5 a.m. CBSSN — Sail GP: The Emirates Dubai Sail Grand Prix - Day 1, Dubai, United Arab Emirates 5 a.m. (Sunday) CBSSN — Sail GP: The Emirates Dubai Sail Grand Prix - Day 2, Dubai, United Arab Emirates SOCCER (MEN’S) 7:30 a.m. USA — Premier League: Chelsea at Leicester City 9 a.m. CBSSN — Serie A: Inter Milan at Hellas Verona 10 a.m. USA — Premier League: Brighton & Hove Albion at Bournemouth Noon CBS — USL Championship: Rhode Island at Colorado Springs, Final 12:30 p.m. NBC — Premier League: Tottenham Hotspur at Manchester City 7 p.m. FS2 — Saudi Pro League: Al Hilal at Al Khaleej (Taped) SOCCER (WOMEN’S) 8 p.m. CBS — NWSL Playoffs: Orlando vs. Washington, Final, Kansas City, Mo. TENNIS 7 a.m. TENNIS — Davis Cup Finals Semifinal The Associated Press created this story using technology provided by Data Skrive TV listings provided by LiveSportsOnTV . (All times Eastern) Schedule subject to change and/or blackouts Sunday, Nov. 24 COLLEGE BASKETBALL (MEN’S) 10:30 a.m. ESPNU — ESPN2 — Myrtle Beach Invitational: TBD, Seventh-Place Game, Conway, S.C. 11 a.m. CBSSN — St. John’s vs. Georgia, Nassau, Bahamas 1 p.m. CBSSN — Rutgers at Kennesaw St. ESPN — Villanova vs. Maryland, Newark, N.J. ESPN2 — Myrtle Beach Invitational: TBD, Third-Place Game, Conway, S.C. 3 p.m. CBSSN — Greenbrier Tip-Off: TBD, Third-Place Game, West White Sulphur Springs, W.V. ESPN — Charleston Classic: TBD, Third-Place Game, Charleston, S.C. 3:30 p.m. ESPN2 — Florida St. vs. UMass, Uncasville, Conn. 5:30 p.m. CBSSN — Greenbrier Tip-Off: TBD, Championship, West White Sulphur Springs, W.V. ESPN — Myrtle Beach Invitational: TBD, Championship, Conway, S.C. 6 p.m. ESPN2 — Charleston Classic: TBD, Fifth-Place Game, Charleston, S.C. ESPNU — Yale vs. Delaware, Uncasville, Conn. 8 p.m. ESPN2 — Myrtle Beach Invitational: TBD, Fifth-Place Game, Conway, S.C. 8:30 p.m. ESPN — Charleston Classic: TBD, Championship, Charleston, S.C. COLLEGE BASKETBALL (WOMEN’S) 1 p.m. PEACOCK — South Florida vs. Louisville, Lake Buena Vista, Fla. 4 p.m. ACCN — Bethune-Cookman at Virginia BTN — Washington St. at Iowa FS1 — South Carolina at UCLA COLLEGE FIELD HOCKEY 1:30 p.m. ESPNU — NCAA Tournament: TBD, Championship, Ann Arbor, Mich. COLLEGE FOOTBALL 12:30 p.m. ESPNU — FCS Football Selection Show COLLEGE VOLLEYBALL (WOMEN’S) Noon ACCN — Stanford at North Carolina 2 p.m. ACCN — California at Duke SECN — South Carolina at Tennessee 3:30 p.m. ESPNU — Southwestern Athletic Tournament: TBD, Championship, Grambling, La. 4 p.m. SECN — Arkansas at Kentucky 6 p.m. SECN — Auburn vs. Oklahoma 7:30 p.m. BTN — Indiana at Ohio St. 8:30 p.m. ESPNU — Mid-Eastern Athletic Tournament: TBD, Championship, Dover, Del. FIGURE SKATING 4 p.m. NBC — ISU: The 2024 Cup of China, Chongqing, China GOLF 1 p.m. GOLF — PGA Tour: The RSM Classic, Final Round, Sea Island Golf Club - Seaside Course, Sea Island, Ga. NBC — LPGA Tour: The CME Group Tour Championship, Final Round, Tiburon Golf Club, Naples, Fla. HORSE RACING Noon FS1 — NYRA: America’s Day at the Races 4 p.m. FS2 — NYRA: America’s Day at the Races NBA G-LEAGUE BASKETBALL 1 p.m. NBATV — Capital City at Maine NFL FOOTBALL 1 p.m. CBS — Regional Coverage: New England at Miami, Tampa Bay at N.Y. Giants, Kansas City at Carolina, Tennessee at Houston FOX — Regional Coverage: Minnesota at Chicago, Detroit at Indianapolis, Dallas at Washington 4:05 p.m. CBS — Denver at Las Vegas 4:25 p.m. FOX — Regional Coverage: San Francisco at Green Bay, Arizona at Seattle 8:20 p.m. NBC — Philadelphia at L.A. Rams PEACOCK — Philadelphia at L.A. Rams NHL HOCKEY 7 p.m. NHLN — Utah at Toronto SAILING 5 a.m. CBSSN — Sail GP: The Emirates Dubai Sail Grand Prix - Day 2, Dubai, United Arab Emirates SOCCER (MEN’S) 9 a.m. USA — Premier League: Liverpool at Southampton 11:30 a.m. USA — Premier League: Manchester United at Ipswich Town 11:45 a.m. FS2 — Saudi Pro League: Al Fateh at Al Ittihad Noon ABC — Spanish Primera Division: Real Madrid at CD Leganés 6 p.m. FS1 — MLS Cup Western Conference Semifinal: Minnesota at L.A. Galaxy TENNIS 10 a.m. TENNIS — Davis Cup Finals Championship The Associated Press created this story using technology provided by Data Skrive TV listings provided by LiveSportsOnTV .
Netherlands advances to its 1st Davis Cup title match, sweeping GermanyNone
Antimicrobial Susceptibility Testing Market to Exhibit a Remarkable CAGR of 5.90% by 2029, Size, Share, Trends, Key Drivers, Demand, Opportunity Analysis and Competitive OutlookThe outcome of the 2024 election has resulted in no shortage of Democratic finger-pointing. While the postmortem and soul-searching are necessary, the tone and tenor of the blame game have begun to morph into something more insidious. In the last weeks we have seen an increasing demand for the Democratic Party to abandon its association with political issues reflecting the “identity” of marginalized or vulnerable communities. While few constituencies have been spared recrimination, some of the most cynical and pernicious scapegoating has been reserved for the transgender community. This is deeply troubling because trans people are particularly vulnerable; with an estimated population of 1.6 million people nationwide, they are barely half of 1% of the U.S. adult population. Transgender people face a disproportionate amount of discrimination. In the last year, more than 500 anti-trans laws were introduced in state legislatures. Over $215 million was spent on political ads demonizing trans people — despite polling showing trans-related issues were not a top priority for most voters. And even Congress is forming its own anti-trans brigade to ban the country’s first trans congresswoman from using the U.S. Capitol’s bathrooms. Trans issues are not fringe issues. Equality, dignity and the ability to control our own bodies are interlinked for all of us, but especially for the trans community. That’s why on Wednesday, the American Civil Liberties Union, where I serve as executive director, argued a landmark case before the Supreme Court regarding the constitutional rights of families with trans children. United States v. Skrmetti will decide whether Tennessee violates equal protection by enacting a sweeping health care ban preventing adolescents, parents and doctors from making decisions around gender-affirming health care. That the court has decided to take up this case demonstrates that how we treat trans people in law and society is important for all of us. Conservatives’ focus on trans rights is merely the next front in the attacks that brought about the overturning of Roe v. Wade. There is a throughline between trans rights and abortion rights: When the Supreme Court heard Dobbs v. Jackson Women’s Health, the justices were deciding whether a state could ban a form of healthcare that saved lives — just as they will in Skrmetti. By targeting one of the nation’s most vulnerable communities, conservatives are hoping the American people will shrug and let them do as they please. The recent retrenchment on the political left and center may set back the cause of trans equality — and equal protection more broadly. Pundits are saying we need to course correct because we have moved too far left. Some will even argue that bringing a Supreme Court case on trans rights — at this moment — isn’t politically savvy. But everyone deserves civil rights and civil liberties, even if the group being targeted does not poll well among likely voters. As the election postmortems continue, people should remember that the struggle for equality is rarely politically expedient or popular — especially at the outset. As a gay man, I vividly remember hearing from the Democratic establishment that gay equality was a losing proposition in the political arena. LBGTQ+ people understood that the Defense of Marriage Act, “Don’t Ask Don’t Tell” and California’s Proposition 8 were little more than rationalizations and gussied-up prejudice. Looking further back, the struggles for civil rights and women’s equality were also unpopular with the public — especially White men — at their inception. It’s not a new phenomenon when voters in some states zealously resist any extension of federal civil rights into their communities. Fighting for trans rights is not hard or complicated for those of us who believe everyone has the right to live free from discrimination. The next generation has far more expansive views on LGBTQ+ issues and trans rights than many of the old guard who populate the top rungs of political parties and institutions today. They will remember the organizations and people who showed conviction and courage in this moment. Meanwhile, history is unlikely to look kindly upon the so-called leaders who chased polls and popularity at the expense of progress and principles. Betting on the future and fighting for trans equality is not just the right call — it’s an easy choice. Anthony D. Romero is the executive director of the ACLU. ©2024 Los Angeles Times. Distributed by Tribune Content Agency, LLC.
Analyzing multiple mammograms improves breast cancer risk prediction December 5, 2024 Washington University School of Medicine A new method of analyzing mammograms identified individuals at high risk of developing breast cancer more accurately than the standard, questionnaire-based method did. The new method, powered by artificial intelligence, could help diagnose cancer earlier and guide recommendations for earlier screening, additional imaging or risk-reducing medications. Facebook Twitter Pinterest LinkedIN Email A new study from Washington University School of Medicine in St. Louis describes an innovative method of analyzing mammograms that significantly improves the accuracy of predicting the risk of breast cancer development over the following five years. Using up to three years of previous mammograms, the new method identified individuals at high risk of developing breast cancer 2.3 times more accurately than the standard method, which is based on questionnaires assessing clinical risk factors alone, such as age, race and family history of breast cancer. The study is published Dec. 5 in JCO Clinical Cancer Informatics . "We are seeking ways to improve early detection, since that increases the chances of successful treatment," said senior author Graham A. Colditz, MD, DrPH, associate director of Siteman Cancer Center, based at Barnes-Jewish Hospital and WashU Medicine, and the Niess-Gain Professor of Surgery. "This improved prediction of risk also may help research surrounding prevention, so that we can find better ways for women who fall into the high-risk category to lower their five-year risk of developing breast cancer." This risk-prediction method builds on past research led by Colditz and lead author Shu (Joy) Jiang, PhD, a statistician, data scientist and associate professor of surgery in the Division of Public Health Sciences at WashU Medicine. The researchers showed that prior mammograms hold a wealth of information on early signs of breast cancer development that can't be perceived even by a well-trained human eye. This information includes subtle changes over time in breast density, which is a measure of the relative amounts of fibrous versus fatty tissue in the breasts. For the new study, the team built an algorithm based on artificial intelligence that can discern subtle differences in mammograms and help identify those women at highest risk of developing a new breast tumor over a specific timeframe. In addition to breast density, their machine-learning tool considers changes in other patterns in the images, including in texture, calcification and asymmetry within the breasts. "Our new method is able to detect subtle changes over time in repeated mammogram images that are not visible to the eye," said Jiang, yet these changes hold rich information that can help identify high-risk individuals. At the moment, risk-reduction options are limited and can include drugs such as tamoxifen that lower risk but may have unwanted side effects. Most of the time, women at high risk are offered more frequent screening or the option of adding another imaging method, such as an MRI, to try to identify cancer as early as possible. "Today, we don't have a way to know who is likely to develop breast cancer in the future based on their mammogram images," said co-author Debbie L. Bennett, MD, an associate professor of radiology and chief of breast imaging for the Mallinckrodt Institute of Radiology at WashU Medicine. "What's so exciting about this research is that it indicates that it is possible to glean this information from current and prior mammograms using this algorithm. The prediction is never going to be perfect, but this study suggests the new algorithm is much better than our current methods." AI improves prediction of breast cancer development The researchers trained their machine-learning algorithm on the mammograms of more than 10,000 women who received breast cancer screenings through Siteman Cancer Center from 2008 -- 2012. These individuals were followed through 2020, and in that time 478 were diagnosed with breast cancer. The researchers then applied their method to predict breast cancer risk in a separate set of patients -- more than 18,000 women who received mammograms through Emory University in the Atlanta area from 2013 -- 2020. Subsequently, 332 women were diagnosed with breast cancer during the follow-up period, which ended in 2020. According to the new prediction model, women in the high-risk group were 21 times more likely to be diagnosed with breast cancer over the following five years than were those in the lowest-risk group. In the high-risk group, 53 out of every 1,000 women screened developed breast cancer over the next five years. In contrast, in the low-risk group, 2.6 women per 1,000 screened developed breast cancer over the following five years. Under the old questionnaire-based methods, only 23 women per 1,000 screened were correctly classified in the high-risk group, providing evidence that the old method, in this case, missed 30 breast cancer cases that the new method found. The mammograms were conducted at academic medical centers and community clinics, demonstrating that the accuracy of the method holds up in diverse settings. Importantly, the algorithm was built with robust representation of Black women, who are usually underrepresented in development of breast cancer risk models. The accuracy for predicting risk held up across racial groups. Of the women screened through Siteman, most were white, and 27% were Black. Of those screened through Emory, 42% were Black. In ongoing work, the researchers are testing the algorithm in women of diverse racial and ethnic backgrounds, including those of Asian, southeast Asian and Native American descent, to help ensure that the method is equally accurate for everyone. The researchers are working with WashU's Office of Technology Management toward patents and licensing on the new method with the goal of making it broadly available anywhere screening mammograms are provided. Colditz and Jiang also are working toward founding a start-up company around this technology. Jiang S, Bennett DL, Rosner BA, Tamimi RM, Colditz GA. Development and validation of a dynamic 5-year breast cancer risk model using repeated mammograms. JCO Clinical Cancer Informatics. Dec. 5, 2024. This work was supported by Washington University School of Medicine in St. Louis. Jiang and Colditz have patents pending related to this work, predicting disease risk using radiomic images. Story Source: Materials provided by Washington University School of Medicine . Original written by Julia Evangelou Strait. Note: Content may be edited for style and length. Journal Reference : Cite This Page :The Milwaukee Bucks' recent run of winning has quieted their desperation for a trade. However, the team still could use an upgrade defensively. The pool of players who are eligible to be traded will grow significantly on December 15th. The Bucks most likely won't hesitate to initiate trade discussions after that deadline. If the Bucks early-season woes return, there could be a roster overhaul. Though an overhaul appears highly unlikely at this moment, as Giannis Antetokounmpo remains committed to the franchise that drafted him 11 years ago. In the event of an Antetokounmpo trade request, Brook Lopez could be involved in a subsequent move. It is safe to assume that the 36-year-old would not want to remain on a rebuilding Bucks team at this stage of his career. NBC Sports recently released a list of possible Los Angeles Lakers trade candidates, which included the Bucks center. "...the long shot — if things really fall apart in Milwaukee — would the Bucks moving on from Brook Lopez (that seems unlikely)." The Lakers are 10-6 and sit just two games back of the Western Conference leaders," the article stated. "A Brook Lopez trade would solidify their center depth behind Anthony Davis as they prepare for a championship run." The two big men could also play alongside each other, as they both space the floor. Lopez particularly does so on relatively low usage, which would open up the offense for Davis and LeBron James. The specifics of a deal could look similar to the following: Lakers receive: Brook Lopez, Tyler Smith Bucks receive: Jarred Vanderbilt, Cam Reddish, Gabe Vincent, 2029 first-round pick, 2025 second-round pick Milwaukee does this trade assuming an Antetokounmpo trade request has happened. As they enter a rebuild, this deal nets them first-round draft capital along with a second-rounder in a deeply talented class. Meanwhile, Vanderbilt is a 25-year-old athletic rim protector who could grow into Milwaukee's backup center of the future. Reddish is also 25 years old and could grow into a bench wing during the hypothetical rebuild. Additionally, Vincent is a cromulent 28-year-old bench point guard but was mainly included for salary-matching. The Lakers should certainly not anticipate Lopez becoming available, as the Bucks and coach Doc Rivers rely on the stretch five heavily. MORE BUCKS NEWS: Bucks predicted to cut ties with regressing All-Star via trade with MagicThe Detroit Lions are facing a Chicago Bears team that are coming off of another tough loss. Related Articles Detroit Lions | Grading the Lions’ Week 12 win, as the defense smothers the Colts Detroit Lions | Lions rush for 3 scores and use stingy defense to beat Colts 24-6 for 9th straight win Detroit Lions | Takeaways as Lions cruise past Colts, 24-6, despite injuries piling up Detroit Lions | Photo gallery from the Lions’ 24-6 road win over the Colts Detroit Lions | Lions place Ennis Rakestraw on IR, activate Emmanuel Moseley Despite tying the game late, the Bears went on to lose to the Vikings in overtime, 30-27, dropping their fifth consecutive game and dipping their record to 4-7. For Dan Campbell’s squad, three key contributors may not be available, especially with the upcoming game occurring just four days after a 24-6 win against the Indianapolis Colts. Detroit’s fourth-year head coach expressed, “It’s going to come down to the wire with a number of them. That’s the challenge with the short week. The good news is, I think most of these are not some long-term thing, but the problem is three days to turn around and play. That’s where it becomes a bit of an issue. So, if we can’t, we’re prepare like we always are. Next man up. You got to hold the line, do your job and go compete.” When asked specifically about which three players are the toughest to decide upon, Campbell noted three key players who have helped the team win nine consecutive games may not suit up. “Right now, I mean, Decker, CD (Carlton Davis), Leaf (Kalif Raymond). Saint’s (Amon-Ra St. Brown) a little banged up. We’ll see how he recovers.” For the Lions, the message this week is about healing up and preparing mentally for another NFC North matchup. Detroit has not won on Thanksgiving since back in 2016. Quarterback Jared Goff expressed postgame the seven-game losing streak is one the current team would like to end. “Message is really recovery. Rest, recovery and the mental work,” said Campbell. “It’s how fast can you recover, get your body right, get your mind focused on the job at hand, because you’re not going to get the physical. Block out all the distractions. That’s one thing, the distractions are on us, not on them. We got all our family here, friends, all that. You got to block it out, tell them you love them, and you’ll see them him after the game. “That’s kind of the challenge with all this,” Campbell continued. “This team’s been in, they’ve lost a couple of heartbreakers in the last two weeks. But they’ve been in a bunch of these tight races, and they just keep coming back for more. So they’re hungry for a win. We got our hands full.” This article was produced by the staff at Detroit Lions On SI. For more, visit si.com/nfl/lions
Josh Hubbard scored 25 points and Claudell Harris Jr. scored 21 on 6-of-9 shooting as Mississippi State escaped with a 91-84 win against Prairie View A&M on Sunday in Starkville, Miss. Prairie View A&M took a 65-64 lead with 10:38 remaining, but Hubbard and Harris Jr. each scored seven points to power the ensuing 14-1 run that put Mississippi State up for good. Hubbard punctuated the rally with a 3-pointer that made it 78-66 with 5:51 to play. The Bulldogs (8-1) stretched their lead to as many as 13 points in the closing minutes to notch their second straight win. Shawn Jones Jr. added 11 points for Mississippi State, while Michael Nwoko added 10 points and 10 rebounds. RJ Melendez also netted 10 points. The Panthers (1-8) were led by the trio of Nick Anderson (21 points) Tanahj Pettway (20) and Marcel Bryant (19). Pettway drilled 4 of 5 3-pointers and Bryant grabbed seven rebounds. Prairie View A&M got off to a hot start, opening up a 27-12 lead with 10:42 left in the first half. It was a surprising haymaker from the visitors, who entered the game winless in Division I play and faced a Bulldogs team that was ranked last week. Mississippi State eventually found its stride offensively, turning things around with a 32-17 run to tie the game at 44 entering halftime. The Bulldogs shot 50 percent from the field overall in the first half, but only made six of their 17 attempts from 3-point range (35.3 percent). Their defense remained an issue throughout the half, with the Panthers hitting 16 of their 27 shots (59.3 percent) and canning 5 of 8 3-pointers. Neither team led by more than five early in the second half until Mississippi State pulled away. The Bulldogs finished the game shooting 55.6 percent from the floor (30-of-54) and drilled 11 of 26 attempts (42.3 percent) from long range. They outrebounded Prairie View A&M 35-22 and outscored them 31-20 in bench points. The Panthers held a 34-32 advantage in points in the paint and shot 56.4 percent overall for the game, including 52.6 percent (10-of-19) on threes. --Field Level Media
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