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BEIRUT (AP) — Thousands of people fled the central Syrian city of Homs, the country’s third largest, as insurgents seized two towns on the outskirts Friday, positioning themselves for an assault on a potentially major prize in their march against President Bashar Assad. The move, reported by pro-government media and an opposition war monitor, was the latest in the stunning advances by opposition fighters over the past week that have so far met little resistance from Assad’s forces. A day earlier, fighters captured the central city of Hama , Syria’s fourth largest, after the army said it withdrew to avoid fighting inside the city and spare the lives of civilians. The insurgents, led by the jihadi Hayat Tahrir al-Sham group, or HTS, have vowed to march to Homs and the capital, Damascus, Assad’s seat of power. Videos circulating online showed a highway jammed with cars full of people fleeing Homs, a city with a large population belonging to Assad’s Alawite sect, seen as his core supporters. If Assad’s military loses Homs, it could be a crippling blow. The city, parts of which were controlled by insurgents until 2014, stands at an important intersection between Damascus and Syria’s coastal provinces of Latakia and Tartus, where Assad enjoys wide support. Homs province is Syria’s largest in size and borders Lebanon, Iraq and Jordan. The city is also home to one of Syria’s two state-run oil refineries. Pressure on the government intensified from multiple directions. Opposition protesters stormed security posts and army positions in the southern province of Sweida, opposition activists said. U.S.-backed Kurdish forces who control eastern and northeastern Syria began to encroach on government-held territory. Offensive leaves Assad reliant on Russia After years of largely being bottled up in a northwest corner of the country, the insurgents burst out a week ago, captured the northern city of Aleppo, Syria’s largest , and have kept advancing since. Government troops have repeatedly fallen back. The sudden offensive has flipped the tables on a long-entrenched stalemate in Syria’s nearly 14-year-old civil war. Along with HTS, the fighters include forces of an umbrella group of Turkish-backed Syrian militias called the Syrian National Army. Turkey has denied backing the offensive , though experts say insurgents would not have launched it without the country's consent. HTS’s leader, Abu Mohammad al-Golani, told CNN in an exclusive interview Thursday from Syria that Assad’s government was on the path to falling, propped up only by Russia and Iran. “The seeds of the regime’s defeat have always been within it,” he said. “But the truth remains, this regime is dead.” A key question about Assad’s ability to fight back is how much top ally Russia — whose troops back Assad’s forces — will throw support his way at a time when it is tied up in the war in Ukraine. Russian Foreign Minister Sergey Lavrov said he planned to discuss the developments in Syria with his Turkish and Iranian counterparts at a meeting Friday in the Qatari capital, Doha. In an interview with former Fox News host Tucker Carlson, he said international actors were backing the insurgents’ advances and that he would discuss “the way to cut the channels of financing and arming them.” Meanwhile, Russia’s embassy in Syria issued a notice reminding Russian citizens that they may use commercial flights to leave the country “in view of the difficult military-political situation.” The foreign ministers of Iran, Iraq and Syria — three close allies — gathered Friday in Baghdad to consult on the rapidly changing war. Syrian Foreign Minister Bassam Sabbagh said the current developments may pose “a serious threat to the security of the region as a whole.” Assad opponents move in center, south and east The insurgent fighters on Friday took over the central towns of Rastan and Talbiseh, putting them 5 kilometers (3 miles) from Homs, according to the Britain-based Syrian Observatory for Human Rights, an opposition war monitor. “The battle of Homs is the mother of all battles and will decide who will rule Syria,” said Rami Abdurrahman, the Observatory’s chief. Pro-government Sham FM said the insurgents entered Rastan and Talbiseh without facing any resistance. There was no immediate comment from the Syrian military. The Observatory said Syrian troops had left Homs. But the military denied that in comments reported by the state news agency SANA, saying troops were reinforcing their positions in the city and were “ready to repel” any assault. In eastern Syria, the Kurdish-led Syrian Democratic Forces coalition said it had moved into the government-held half of the city of Deir el-Zour, apparently without resistance. One of the main cities in the east, Deir el-Zour had long been split between the government on the western side of the Euphrates River and the SDF on the eastern side. The SDF also said it took control of further parts of the border with Iraq. That appeared to bring it closer to the government-held Boukamal border crossing. The crossing is a vital for the government because it is the gateway to the corridor to Iran, a supply line for Iran-backed fighters, including Lebanon’s Hezbollah. At the same time, insurgents seized Syria’s sole crossing to Jordan, according to opposition activists. Jordan announced it was closing its side of the crossing. Lebanon also closed all but one of its border crossings with Syria. Worsening economy could hurt Assad’s war effort The opposition assault has struck a blow to Syria’s already decrepit economy. On Friday, the U.S. dollar was selling on Syria’s parallel market for about 18,000 pounds, a 25% drop from a week ago. When Syria’s conflict erupted in March 2011, a dollar was valued at 47 pounds. The drop further undermines the purchasing power of Syrians at a time when the U.N. has warned that 90% of the population is below the poverty line. Syria’s economy has been hammered for years by the war, Western sanctions, corruption and an economic meltdown in neighboring Lebanon, Syria’s main gate to the outside world. Damascus residents told The Associated Press that people are rushing to markets to buy food, fearing further escalation. The worsening economy could be undermining the ability of Syria’s military to fight, as the value of soldiers’ salaries melts away while the insurgents are flush with cash. Syria’s military has not appeared to put up a cohesive counteroffensive against the opposition advances. SANA on Friday quoted an unnamed military official as saying the Syrian and Russian air forces were striking insurgents in Hama province, killing dozens of fighters. Syria’s defense minister said in a televised statement late Thursday that government forces withdrew from Hama as “a temporary tactical measure” and vowed to gain back lost areas. “We are in a good position on the ground,” Gen. Ali Mahmoud Abbas said, saying troops remained “at the gates of Hama.” He spoke before the opposition advanced further south toward Homs. He said the insurgents, whom he described as “takfiri” or Muslim extremists, are backed by foreign countries. He did not name the countries but appeared to be referring to Turkey and the United States. ___ Associated Press writers Albert Aji in Damascus, Syria, and Suzan Fraser in Ankara, Turkey, contributed to this report. Bassem Mroue, The Associated Press
— Court Rules in Favor of Heron in Patent Lawsuit Against Fresenius Kabi USA , LLC — SAN DIEGO , Dec. 3, 2024 /PRNewswire/ -- Heron Therapeutics, Inc. (Nasdaq: HRTX) ("Heron" or the "Company"), a commercial-stage biotechnology company, today announced that the U.S. District Court for the District of Delaware ruled in Heron's favor in the Company's patent litigation against Fresenius Kabi USA , LLC with respect to CINVANTI® (aprepitant) injectable emulsion. The district court found that Heron's U.S. Patent Nos. 9,561,229 and 9,974,794, which expire in 2035, are valid and would be infringed by Fresenius' proposed generic product. The district court decision concludes the litigation initiated in July 2022 in response to Fresenius' submission of an Abbreviated New Drug Application with the U.S. Food and Drug Administration seeking approval of a generic version of CINVANTI®. As a result of the decision, Heron will seek an order from the Court prohibiting Fresenius from launching its generic CINVANTI® until after the expiration of the patents in 2035. This decision is subject to appeal. "We are pleased with this anticipated result of the proceeding and will continue to vigorously defend the CINVANTI® patent estate in the future," said Craig Collard, Chief Executive Officer of Heron. "The team at Heron takes great pride in the result of our successful history of developing injectable products, which is demonstrated by the strength of our intellectual property and the performance of our innovative drugs like CINVANTI® in serving patients with serious unmet needs." About Heron Therapeutics, Inc. Heron Therapeutics, Inc. is a commercial-stage biotechnology company focused on improving the lives of patients by developing and commercializing therapeutic innovations that improve medical care. Our advanced science, patented technologies, and innovative approach to drug discovery and development have allowed us to create and commercialize a portfolio of products that aim to advance the standard-of-care for acute care and oncology patients. For more information, visit www.herontx.com . Forward-looking Statements This news release contains "forward-looking statements" as defined by the Private Securities Litigation Reform Act of 1995. Heron cautions readers that forward-looking statements are based on management's expectations and assumptions as of the date of this news release and are subject to certain risks and uncertainties that could cause actual results to differ materially. Therefore, you should not place undue reliance on forward-looking statements. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in our most recent Annual Report on Form 10-K and any subsequent Quarterly Reports on Form 10-Q, and in our other reports filed with the Securities and Exchange Commission, including under the caption "Risk Factors." Forward-looking statements reflect our analysis only on their stated date, and Heron takes no obligation to update or revise these statements except as may be required by law. Investor Relations and Media Contact: Ira Duarte Executive Vice President, Chief Financial Officer Heron Therapeutics, Inc. iduarte@herontx.com 858-251-4400 View original content to download multimedia: https://www.prnewswire.com/news-releases/us-district-court-upholds-validity-of-cinvanti-patents-302321651.html SOURCE Heron Therapeutics, Inc.Georgia quarterback Carson Beck announced Saturday that he will forgo his final year of eligibility and enter the 2025 NFL Draft. Beck, 22, led the Southeastern Conference with 28 touchdown passes and finished third in the SEC with 3,485 passing yards. He also led the conference in interceptions, however. Beck will be a spectator for the Bulldogs in the College Football Playoff after undergoing surgery Monday to repair the ulnar collateral ligament in his right (throwing) elbow. Gunner Stockton is in line to guide No. 2 seed Georgia into the CFP, starting with the Bulldogs' quarterfinal game against No. 7 seed Notre Dame at the Sugar Bowl on Wednesday in New Orleans. "There's unfinished business still this season and I'll be here to support however I can, finish strong!" Beck said in a statement posted on social media. Beck, a fifth-year senior, finished with a 24-3 record in his career with Georgia. "The past five years at the University of Georgia have been nothing short of a dream come true and I will forever cherish the memories that have been made. Thank you Dawg Nation for the time I've been here and to those who've supported and believed in me, thank you," Beck wrote on social media. "It's been an incredible journey and all these moments have ultimately led me to take the next step in my football career. With that being said, I will be declaring for the 2025 NFL Draft. Go Dawgs!" Beck, the Bulldogs' starter all year, was replaced in the second half of the SEC title game with the injury. Stockton helped to guide the Bulldogs to a 22-19 overtime win over Texas and clinch a first-round bye in the first 12-team playoff. --Field Level Media
The crypto market is gearing up for the next big movers. Five digital currencies stand out as essential considerations for the upcoming quarter. Among them is a promising token built on the Solana blockchain that's attracting a lot of attention. Discover which assets could potentially redefine portfolios and why they shouldn't be overlooked. Catzilla Wrecks Chaos: The Meme Coin for Warriors of Crypto In a world where financial freedom feels out of reach, a new opportunity emerges— Catzilla ! Born from the frenzy of meme culture and set for explosive growth , this is the meme coin investors have been waiting for! A legendary cat warrior with lives to spare, Catzilla offers you 14 chances to grab the power-packed $CATZILLA token before it goes public. Imagine leveling up your stash from Stage 1 to Stage 14, where your gains soar up to 700%! Catzilla evolves as the presale progresses, bringing you closer to financial victory with every step. But beware, fellow warriors—the clock is ticking, and only the swift and the daring will secure their share of Catzilla’s unstoppable might . Claim your share before Catzilla stomps the competition flat! The crypto world’s gone barking mad for years, but now it’s time for cats to claw their way to the top. MEW and Popcat are the latest feline sensations proving that dogs might fetch headlines, but cats bring home the gains. MEW: Purring into the top 15 meme coins, this clever kitty pulled off a 103.7% climb in just three months Popcat: This one didn’t just pounce—it soared, delivering a jaw-dropping 157.44% surge. These aren’t just one-off flukes. Cats are on the prowl , staking their claim in the meme coin kingdom. And if you think MEW and Popcat are impressive, wait until Catzilla roars onto the scene. Forget chasing tails—this is where the real action is. Catzilla is here to destroy the old systems that hold you back. It’s time to build a new world where you, the warriors of the crypto space, rise up and claim what’s yours . With every stage of this presale, the forces of profit grow stronger. Time is running out, and the opportunity to join Catzilla’s army won’t last forever. The profits are set to explode , and only those brave enough to seize this moment will see their gains rise like a true anime hero’s power level . Get in now, watch Catzilla wreck the market, and bring chaos to the competition! Uniswap's UNI Token: Decentralized Governance in DeFi Uniswap's UNI token, launched in September 2020, allows holders to influence the platform's development by voting on proposals related to fee structures and token distribution. This move responded to competition from SushiSwap, with Uniswap distributing 150 million UNI tokens to past users, each receiving 400 UNI tokens valued over $1,000 at launch. Since 2018, Uniswap has operated as a decentralized exchange on the Ethereum blockchain, using an automated liquidity protocol that enables trading without an order book. Users maintain full control of their funds, and the platform's open-source nature allows free token listing. With over $3 billion in assets, Uniswap stands as the fourth-largest DeFi platform, highlighting the UNI token's significance in the current market. Shiba Inu: An Ethereum-Based Memecoin with Growing Utility Shiba Inu (SHIB) is an Ethereum-based cryptocurrency inspired by Dogecoin. Launched in August 2020 by an anonymous developer named Ryoshi, it began with a supply of 1 quadrillion tokens. Half of these tokens were sent to Ethereum co-creator Vitalik Buterin, who donated a significant portion to the India Covid Crypto Relief Fund and burned 40% of the total supply. SHIB's integration with Ethereum allows for applications like ShibaSwap, a decentralized exchange. Plans include a future NFT platform and a DAO-based governance system. This positions SHIB for broader utility in the crypto space. In the current market cycle, SHIB's expanding ecosystem adds to its appeal. Worldcoin (WLD): Advancing Global Digital Identity Through Biometrics Worldcoin (WLD) is a cryptocurrency introduced in 2023 that aims to revolutionize digital identity and financial inclusion. Co-founded by Sam Altman, it utilizes eye-scanning technology through a device called the Orb to create unique, secure digital IDs for individuals worldwide. With a fixed supply of 10 billion tokens, Worldcoin focuses on fair wealth distribution and universal access to the digital economy. It has attracted over two million users and plans significant funding to value the token at $3 billion. While privacy concerns due to biometric data use have led to investigations in several countries, Worldcoin's innovative approach positions it as a notable player in the crypto space. Understanding Raydium (RAY): A Key Player on Solana Blockchain Raydium (RAY) is the native token of Raydium, a decentralized exchange and automated market maker built on the Solana blockchain. Raydium offers fast and low-cost token swaps by leveraging Solana's high-performance network. The RAY token is used for governance, staking, and earning rewards within the platform. The technology aims to improve liquidity provision and trading efficiency in the decentralized finance ecosystem. Given Solana's growing adoption and Raydium's role in the DeFi space, RAY may have potential in the current market. However, its attractiveness depends on overall market trends and investor interest in DeFi projects. Conclusion While UNI, SHIB, WLD, and RAY offer some opportunities, their short-term potential seems limited. In contrast, Catzilla stands out as the ultimate meme coin hero aiming for financial freedom for all. With a remarkable 700% ROI potential during its presale and triple utility features, it invites crypto enthusiasts to join the fight against crypto villains. Site: Catzilla ($CATZILLA) Twitter: https://x.com/CatzillaToken Telegram: Telegram Chat Telegram News Join our WhatsApp Channel to get the latest news, exclusives and videos on WhatsApp _____________ Disclaimer: Analytics Insight does not provide financial advice or guidance. Also note that the cryptocurrencies mentioned/listed on the website could potentially be scams, i.e. designed to induce you to invest financial resources that may be lost forever and not be recoverable once investments are made. You are responsible for conducting your own research (DYOR) before making any investments. Read more here.
By KATE BRUMBACK ATLANTA (AP) — A judge is weighing whether a Georgia state Senate committee has the right to subpoena testimony and documents from Fulton County District Attorney Fani Willis as it looks into whether she has engaged in misconduct during her prosecution of President-elect Donald Trump. The Republican-led committee sent subpoenas to Willis in August seeking to compel her to testify at its September meeting and to produce scores of documents. The committee was formed earlier this year to examine allegations of “various forms of misconduct” by Willis, an elected Democrat, during her prosecution of Trump and others over their efforts to overturn the former president’s 2020 election loss in Georgia. Willis’ attorney, former Democratic Gov. Roy Barnes, told Fulton County Superior Court Judge Shukura Ingram during a hearing Tuesday that although the Georgia General Assembly has subpoena power, that power is not automatically conferred on a single legislative chamber or its committees. Even if the committee did have such power, he argued, the subpoenas in question are overly broad and not related to a legitimate legislative need. Barnes said the focus on Willis and her investigation into Trump shows that the committee was politically motivated and not a legitimate inquiry into the practices of district attorneys’ offices: “What they were trying to do is chill the prosecution of Donald Trump and find out what they had.” Josh Belinfante, a lawyer representing the lawmakers, said there is nothing in the Georgia Constitution that prohibits the Senate from issuing a subpoena. The duly formed interim committee is looking into whether new legislation is needed to regulate the practices of district attorneys’ offices in the state, he argued. “They are investigating and making an inquiry into these allegations that may show that existing state laws, including those establishing the processes for selecting, hiring and compensating special assistant district attorneys, are inadequate,” Belinfante said. The resolution creating the committee focused in particular on Willis’ hiring of special prosecutor Nathan Wade , with whom she had a romantic relationship , to lead the prosecution against Trump and others. It says the relationship amounted to a “clear conflict of interest and a fraud upon the taxpayers” of the county and state. One of the committee’s subpoenas orders Wills to produce documents related to Wade, including documents related to his hiring and payment, documents related to money or items of value that Wade and Willis may have exchanged, text messages and emails between the two, and their phone records. The committee also requested any documents her office sent in response to requests from the U.S. House, as well as communications Willis and her office had with the White House, the U.S. Justice Department and the House relating to the 2020 presidential election. And they asked for documents related to federal grant money Willis’ office has received. Before the deadlines in the subpoenas, Willis challenged them in court. Willis’ challenge was pending in mid-September when she skipped a hearing during which the committee members had hoped to question her. In October, the committee asked Ingram to require Willis to comply with the subpoenas. The committee’s lawyers wrote in a court filing that Willis’ failure to do so had delayed its ability to finish its inquiry and to provide recommendations for any legislation or changes in appropriations that might result. Barnes also argued that once the regular legislative session has adjourned, which happened in March this year, legislative committees can meet to study issues and come up with recommendations but do not have the power to compel someone to appear or produce documents. Belinfante rejected that, saying the state Constitution expressly permits the creation of interim committees and allows them to make their rules. Even if these subpoenas were validly issued, Barnes argued, they ask for too much, including private and personal information that is not a legitimate target of a legislative subpoena. Related Articles National News | Are you a former SmileDirectClub customer? You might be eligible for a refund National News | Justice Department announces sweeping reforms to curb suicides in federal prisons and jails National News | Defense makes closing argument in murder trial of Cash App founder Bob Lee National News | A judge has once again rejected Musk’s multi-billion-dollar Tesla pay package. Now what? National News | Is Enron back? If it’s a joke, some former employees aren’t laughing Belinfante said the lawmakers are simply trying to do their jobs. He asked that Willis be ordered to appear before the committee in early January. He also asked that she be ordered to provide the requested documents and explain what privilege justifies any that are excluded. With a glaring lack of state case law on the issue of the General Assembly’s subpoena power, that’s one issue Ingram will have to address. She said she will consider the arguments and release her order as soon as she can. Willis and Wade have acknowledged that they had a relationship but have said it began after he was hired and ended before the indictment against Trump was filed. Trump and other defendants argued that the relationship created a conflict of interest that should disqualify Willis and her office from continuing with her prosecution of the case. Fulton County Superior Court Judge Scott McAfee ruled in March that Willis’ actions showed a “tremendous lapse in judgment,” but he did not find a conflict of interest that would disqualify Willis. He said she could continue her prosecution as long as Wade stepped aside, which he did. Trump and others have appealed that ruling to the Georgia Court of Appeals, and that appeal remains pending.Boonsong release stirs flap
Whitcomb triple-double propels the 8-0 Spirit to best start in its historySunderland professor studies Paddington stories' attitudes toward migration
