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live casino westmoreland mall The assistant secretary of the Navy for research, development and acquisition and the Department of the Navy chief information officer have designated , or NESD, as the naval enterprise IT service for service desk capabilities and support, and designated as the naval enterprise IT service for Amazon Web Services GovCloud for DON research, development, test and evaluation missions that require acquisition and consumption of cloud services. Table of Contents NESD & COSMOS Managed by the Program Executive Office for Digital and Enterprise Services, NESD is a centralized support center powered by artificial intelligence and machine learning. For its part, COSMOS is an AWS Impact Level 4/5 unclassified GovCloud environment that enables users to self-onboard, build and secure non-production workloads. Managed by the Naval Information Warfare Center Pacific Service Center, COSMOS adheres to a zero trust security model. Enterprise IT Services NESD and COSMOS are two of four enterprise IT services designated by DON CIO . Such services or service offerings are mature technologies that can be paired with appropriate use cases. “Enterprise information technology services are a huge force multiplier: these services allow our entire enterprise the ability to do more for less with greater security, quality and speed,” Rathbun, a 2024 awardee, said. The designations of NESD and COSMOS are part of the DON’s overall efforts to transition from isolated, duplicative IT functions toward enterprise IT capabilities.Winston's performance in snowy win over Steelers adds new layer to Browns' quarterback conundrum

Fortnite fans are looking forward to the release of update 33.10, which will introduce a boatload of new content. Available on PS5, PlayStation 4, Xbox Series X|S, Nintendo Switch, Android and PC, update 33.10 will be available to download and install on the morning of December 10. As a numbered update, the download will be accompanied by an extended period of server downtime, which means you won't be able to play Fortnite, LEGO Fortnite, Rocket Racing and Fortnite Festival for at least a couple of hours. If you want to know when you can log back into Fortnite, check out the 33.10 server maintenance schedule below. READ MORE: Fortnite update 33.10 patch notes, downtime, first-person Ballistic mode, LEGO Brick Life According to Epic Games , Fortnite Battle Royale and all of its companion game modes will be taken offline in full at 9am GMT. However, as Epic points out in a tweet announcing the downtime, matchmaking will be disabled at around 8.30am UK time. "Sharpen your blades!" reads an Epic tweet. "Downtime for v33.10 begins at 4 AM ET with matchmaking ending shortly beforehand." Epic hasn't revealed exactly when downtime will come to an end, but maintenance typically lasts for at least a couple of hours. Judging by the amount of new content launching as part of update 33.10, expect downtime to come to an end at around midday. In terms of what fans can expect from the update, Epic has officially confirmed plans to bring a new first-person mode to the game. Fortnite Ballistic is a new first-person shooter mode featuring 5v5 battles with ranked and unranked modes. Described as a tactical game mode where teamwork is key, it will launch with the Skyline 10 map. Epic explains more: "Ballistic is launching with the Skyline 10 map, a starting set of weapons, and a limited number of items. Adjustments will be made beyond launch based on player feedback, in addition to major updates such as new maps, weapons, and features." The game is a no-build mode where all presets from your Locker will carry over. It supports existing skins and items, except for Pickaxes, Contrails, Instruments, Vehicles and Jam Tracks. There's also a new Text chat upgrade, as well as a LEGO social role-playing mode called Brick Tales. Daily Express will update this article when server downtime comes to an end.SYM INVESTOR ALERT: Robbins Geller Rudman & Dowd LLP Announces that Symbotic Inc. Investors with Substantial Losses Have Opportunity to Lead the Symbotic Class Action Lawsuit

California researchers say the world may be just one genetic tweak away from human-to-human transmission of the H5N1 bird flu virus — a worrisome mutation that could open the door to widespread human infections and possibly even a pandemic, according to some experts. In a study published Thursday in the journal Science, Scripps Research Institute biologists determined that a single mutation of the hemagglutinin protein — the “H” in H5N1 — could transform a virus that has so far sickened or killed mostly birds and cows into a pathogen that targets cells in human beings. The finding comes amid a growing number of H5N1 outbreaks among California dairy cows, as well as a state-ordered recall of raw milk products . Since the virus began infecting the nation’s dairy stock in March, infectious disease experts have warned that unprotected contact between dairy workers and infected cows could enable the virus to evolve in a manner that threatens humans. Now, Scripps researchers suggest the path for such a genetic change may be much shorter than state and national health officers anticipated. “This really surprised us,” said study coauthor James Paulson, a biochemist and molecular biologist. This one mutation “satisfies a requirement for transmission,” he said. Richard Webby, director of the World Health Organization’s Collaborating Center for Studies on the Ecology of Influenza in Animals and Birds, said the study’s finding countered prevailing thought on the virus — specifically, that it would take multiple mutations for the virus to pose a threat to humans. “This will likely cause a stir,” said Webby, who is also a researcher in the department of infectious diseases at St. Jude Children’s Research Hospital in Memphis, Tenn., and was not involved in the Scripps research. “I think most of us thought it would probably need more than one change,” Webby said. Yoshihiro Kawaoka, a virologist at the University of Wisconsin-Madison and the University of Tokyo, called the Scripps teams’ finding a “significant discovery” and said it was “critical because, given the mutation rate of influenza viruses, one in every 10,000 particles of the bovine H5N1 virus could carry this mutation.” That means the potential emergence of an H5N1 virus “that can recognize human receptors is closer than we may have thought,” he said. Several months ago, Paulson and coauthor Ian Wilson, a Scripps structural biologist, decided they’d investigate the current H5N1 strain, and see what it would take for it to cause a human pandemic. Paulson is an expert in researching where and how different influenza viruses bind to cells when they enter a host. Wilson studies the structure of influenza virus proteins. The scientists began their research by accessing a global influenza database and locating the genetic sequence for A/Texas/37/2024 — the strain of H5N1 bird flu found in a Texas dairy worker. They then examined the hemagglutinin proteins, or spikes, on the outer surface of the virus, since those enable it to latch onto the cell membrane of its host. Animals such as birds and humans have different docking stations on their cells — known as sialic acid receptors. In order for a flu virus to open a door into a cell and begin replicating, it needs just the right spike, or key. Although more than 50 humans have been infected by H5N1, many of these cases involve dairy workers who were likely sprayed in the eyes and nose with milk from infected cows. Researchers postulate that repeated exposure of this sort allowed the virus to push into the cells — a brute force entry more than a lock-picking. Ordinarily, person-to-person transmission of a flu virus “is mainly through the air from droplets from a sneeze or cough, which contains very little virus,” Paulson said. “In this context, the virus needs to be able to recognize human-type receptors to bind to cells in the human airway in amounts sufficient to cause infection.” In order to figure out what it would take for the virus to gain the right docking equipment to unleash a human pandemic, Paulson, Wilson and their team looked at previous flu outbreaks that had jumped the bird-human divide, including the influenza outbreaks of 1918, 1957, 1968 and 2009 — as well as some earlier research. They “selected a number of positions” on the hemagglutinin protein “to mutate, one at a time” with amino acids they knew had been implicated in previous pandemics. Then they attempted to bind these altered “H” proteins with human and bird receptor analogues. Lo and behold, when they switched a glutamine to a leucine at position 226, it no longer bound to the bird receptors, but instead exclusively to those of humans. Paulson said it was especially interesting because this mutation had occurred before in earlier strains of H5N1, including one from around 2010 — but “at that time, that single mutation was not sufficient to change receptor specificity. So, the unexpected thing is that virus has changed in subtle ways — evolved, if you will — so that now that single mutation does change the receptor specificity.” Although the researchers demonstrated that it was possible for the virus to become a threat to humans with just one genetic change, that does not mean nature will follow that specific path. A multitude of factors can influence the evolution of an organism, and they are not easily predicted. This may be why the virus has not yet gained the ability to widely infect humans, some say. “Despite more than 50 human infections with bovine H5N1, we have not seen evidence of this virus adapting to humans on a larger scale,” Kawaoka said. “This suggests that ... additional mutations are likely required for the virus to become fully transmissible between humans.” Paulson acknowledged that the “context of the total biological picture is extremely important.” He said the research focused on just “one property that is important for the virus to be successful when adapting to a new host,” but there are others that may also be important. For instance, H5N1 in the past was known to cause severe respiratory disease. But recently, it’s mostly been associated with conjunctivitis and only occasionally with mild, upper respiratory disease in people. “Why is that? I don’t think anybody knows,” Paulson said. What is known is that the virus is moving swiftly through a variety of species around the globe — with ample opportunity to mutate and adapt. As of Thursday, the Centers for Disease Control and Prevention had confirmed H5N1 infections in 58 people: 35 as a result of working with infected dairy cows, 21 from infected poultry, and in two cases, the source is unknown. In addition, 707 dairy herds across 15 states have also been infected. And in just the last 30 days, 23 commercial poultry farms in California have come down with the virus — affecting more than 5.6 million birds. ©2024 Los Angeles Times. Visit at latimes.com . Distributed by Tribune Content Agency, LLC.Valladolid loses again and Getafe ends winless run in La LigaBiden pledges £472m for rail project to improve access to Africa’s minerals

Advisors Asset Management Inc. Reduces Stock Position in Lyft, Inc. (NASDAQ:LYFT)President Joe Biden pledged another 600 million US dollars (£472 million) on Wednesday for an ambitious multi-country rail project in Africa as one of the final foreign policy moves of his administration. Mr Biden told African leaders the resource-rich continent of more than 1.4 billion people had been “left behind for much too long”. “But not anymore,” Mr Biden added. “Africa is the future.” Mr Biden used the third and final day of a visit to Angola – his long-awaited, first trip to sub-Saharan Africa as president – to travel to the coastal city of Lobito and tour an Atlantic port terminal that’s part of the Lobito Corridor railway redevelopment. Mr Biden described it as the largest US investment in a train project outside America. The US and allies are investing heavily in the project that will refurbish nearly 1,200 miles of train lines connecting to the mineral-rich areas of Congo and Zambia in central Africa. The corridor, which likely will take years to complete, gives the US better access to cobalt, copper and other critical minerals in Congo and Zambia that are used in batteries for electric vehicles, electronic devices and clean energy technologies that Mr Biden said would power the future. China is dominant in mining in Congo and Zambia. The US investment has strategic implications for US-China economic competition, which went up a notch this week as they traded blows over access to key materials and technologies. The African leaders who met with Mr Biden on Wednesday said the railway corridor offered their countries a much faster route for minerals and goods – and a convenient outlet to Western markets. “This is a project that is full of hope for our countries and our region,” said Congo President Felix Tshisekedi, whose country has more than 70% of the word’s cobalt. “This is not just a logistical project. It is a driving force for economic and social transformation for millions of our people.” The leaders said the corridor should spur private-sector investment and improve a myriad of related areas like roads, communication networks, agriculture and clean energy technologies. For the African countries, it could create a wave of new jobs for a burgeoning young population. Cargo that once took 45 days to get to the US – usually involving trucks via South Africa – would now take around 45 hours, Mr Biden said. He predicted the project could transform the region from a food importer to exporter. It’s “something that if done right will outlast all of us and keep delivering for our people for generations to come,” he said. The announcement of an additional $600 million took the U.S.’s investment in the Lobito Corridor to 4.0 billion dollars (£3.15 billion).

Penn State pushed hard to get Tyler Warren to New York as a Heisman Trophy finalist . Monday night, those hopes were dashed. Warren was not among four finalists for the award, given each year to the nation’s top player. Colorado wide receiver/defensive back Travis Hunter, Boise State running back Ashton Jeanty, Oregon quarterback Dillon Gabriel and Miami quarterback Cam Ward were the finalists. “He’s done it week in and week out. He’s a big-time player, and he’s doing it when all eyes are on him and he’s the focus of the game plan,” James Franklin said at the end of the season. “He’s a special guy.” Warren has recorded 1,062 yards on 88 receptions with six touchdowns this season. Offensive coordinator Andy Kotelnicki has also done quite a job using Warren in gadget plays, with the Virginia native holding 23 rushes for 191 yards and seven touchdowns. He’s completed three of five passes for 35 yards and a touchdown. He was named first-team All-Big Ten this season and the conference’s top tight end. Warren’s also a finalist for the Mackey Award as the nation’s top tight end and the Paul Hornung Award as the nation’s most versatile player . Among the records Warren has broken this season, he’s now Penn State’s career holder of most receiving touchdowns by a tight end and most yards. He broke the single-season records for yards and receptions by a Nittany Lions tight end. BETTING: Check out our guide to the best PA sportsbooks , where our team of sports betting experts has reviewed the experience, payout speed, parlay options and quality of odds for multiple sportsbooks. Sign up for the PennLive’s Penn State newsletters, the daily Penn State Today and the subscriber-exclusive Penn State Insider Stories by Max Ralph Andy Kotelnicki hints at staying with Penn State despite head-coaching interviews Penn State 'point god' Ace Baldwin Jr. named to national player of the year watch list Freshman Penn State defensive lineman planning to enter transfer portal

Is Enron back? If it's a joke, some former employees aren't laughingLAS VEGAS , Dec. 5, 2024 /PRNewswire/ -- Resorts World Las Vegas LLC announced today the formation of a Board of Directors, with industry veteran Jim Murren as the Chairman, and the appointment of Alex Dixon as its Chief Executive Officer as a key part of the Company's plan to deepen and strengthen its leadership. The new team, with a combined 130 years of experience in the gaming industry, will accelerate the Company's growth strategy and continue its mission to remain Las Vegas's premier resort destination for unmatched luxury and entertainment experiences and unforgettable moments. This announcement underscores Resorts World Las Vegas's path of evolution as the appointments bolster the property's governance structure to help drive the go-forward business strategy. The members of the Board assumed their roles on December 4, 2024 and Dixon will assume his position as CEO effective January 16, 2025 . "As Resorts World Las Vegas continues to establish itself as the premier resort destination in Las Vegas , we are excited to welcome this group of industry leaders overseeing and guiding the Leadership Team to deliver unparalleled guest experiences while fostering our commitment to compliance," said Kok Thay Lim , the Chairman and Chief Executive of Genting Berhad. "With over 40 years of collective experience in the global gaming and hospitality industry, we are confident that Alex and Jim, alongside the Board, will help drive the Company forward in pursuing our strategic goals for years to come." Industry veteran Murren will assume the role of Chairman, bringing a depth of expertise in the global gaming and hospitality industries. He previously served as CEO and Chairman of the Board of Directors at MGM Resorts, where he led the company through a period of expansion and growth. He currently holds leadership positions with Ritz-Carlton Yacht Collection, the General Commercial Gaming Regulatory Authority in the United Arab Emirates , Cirque du Soleil, and Playstudios, as well as serving as a trustee on Howard University's Board of Trustees. Dixon, a Las Vegas native, will assume his role following his tenure as CEO at Q Casino & Resort and Dubuque Racing Association. He has more than 20 years of combined global gaming, hospitality, entertainment, real estate, and banking industries experience across iconic and Fortune 500 businesses, including MGM Resorts International, Caesars Entertainment Corp., and Goldman Sachs & Co. Additionally, Dixon brings extensive experience in building winning teams, developing underutilized real estate, re-invigorating legacy brands, and driving clarity of purpose from the Boardroom to front-line operations. "Resorts World Las Vegas has transformed the Vegas Strip with its unceasing focus on providing the ultimate guest experience, which is why I'm thrilled to join the team and help continue setting the standard for premier hospitality," said Murren. "The Board and I are excited to continue building on the strong foundation set by the Executive Leadership Team and driving continued growth and innovation to benefit all of RWLV's key stakeholders." In addition to Murren as Chairman and independent member, the newly established Board of Directors includes three additional, prominent members, two independent and one non-independent from diverse backgrounds: Dixon added, "We have a bright future ahead of us, and I look forward to supporting and collaborating with Resorts World Las Vegas's leadership alongside the Board to continue showcasing the best the Strip has to offer. We have an incredible team of talented and committed employees throughout the organization and are confident we can achieve amazing things together." For more information about Resorts World Las Vegas, please visit www.rwlasvegas.com . About Resorts World Las Vegas Resorts World Las Vegas LLC is the owner and operator of Resorts World Las Vegas (RWLV), a world-class integrated resort with over 3,500 hotel rooms and suites, and includes a multitude of gaming, convention, retail, food, beverage, and entertainment amenities. Located on approximately 86 acres on the northern end of the Strip, RWLV brings state-of-the-art technology and distinctive entertainment and experiential amenities to Las Vegas . Additionally, the Resort has over 42 acres of undeveloped land, which offers significant growth potential which few of its peers can match. Resorts World Las Vegas LLC is an indirect wholly owned subsidiary of Genting Berhad, an investment holding and management company focused predominantly on the global gaming and hospitality industry. The Genting Group has a track record of close to six decades relating to sourcing, developing and operating integrated resorts in various parts of the world, including in highly rated and regulated jurisdictions such as Malaysia , Singapore , the U.K., the United States and the Bahamas . The Genting Group comprises Genting Berhad (KLSE: Genting) and its listed companies including Genting Malaysia Berhad (KLSE: GENM), Genting Plantations Berhad (KLSE: GENP) and Genting Singapore Limited (SGX: G13), as well as principal unlisted subsidiaries Genting Energy Limited and Resorts World Las Vegas LLC. View original content: https://www.prnewswire.com/news-releases/resorts-world-las-vegas-establishes-board-of-directors-with-jim-murren-as-chairman-appoints-alex-dixon-as-chief-executive-officer-302324364.html SOURCE Resorts World Las Vegas

WASHINGTON (AP) — President-elect pick for intelligence chief fresh scrutiny Monday on Capitol Hill about amid the of that country’s hardline Assad rule. Gabbard ignored shouted questions about her as she ducked into one of several private meetings with senators who are being asked to confirm . But the Democrat-turned-Republican Army National Reserve lieutenant colonel delivered a statement in which she reiterated her support for Trump’s America First approach to national security and a more limited U.S. military footprint overseas. “I want to address the issue that’s in the headlines right now: I stand in full support and wholeheartedly agree with the statements that President Trump has made over these last few days with regards to the developments in Syria,” Gabbard said exiting a Senate meeting. The incoming president’s Cabinet and top administrative choices are dividing his Republican allies and , if not full opposition, from Democrats and others. Not just Gabbard, but other Trump nominees including Pentagon pick Pete Hegseth, were back at the Capitol ahead of what is expected to be volatile confirmation hearings next year. The incoming president is working to put his team in place for an of mass immigrant deportations, firing federal workers and rollbacks of U.S. support for Ukraine and NATO allies. “We’re going to sit down and visit, that’s what this is all about,” said Sen. Mike Rounds, R-S.D., as he welcomed Gabbard into his office. Meanwhile, Defense Secretary pick to be picking up support from once-skeptical senators, the former Army National Guard major denying sexual misconduct allegations and pledging not to drink alcohol if he is confirmed. The president-elect’s choice to lead the FBI, , who has written extensively about locking up Trump’s foes and proposed dismantling the Federal Bureau of Investigation, launched his first visits with senators Monday. “I expect our Republican Senate is going to confirm all of President Trump’s nominees,” said Sen. Tom Cotton, R-Ark., on social media. Despite widespread concern about the nominees’ qualifications and demeanors for the jobs that are among the highest positions in the U.S. government, Trump’s team is portraying the criticism against them as nothing more than political smears and innuendo. Showing that concern, have urged Senate leaders to schedule closed-door hearings to allow for a full review of the government’s files on Gabbard. Trump’s allies have described the in particular as similar to those lodged against Brett Kavanaugh, the former president’s Supreme Court nominee who denied a sexual assault allegation and went on to be confirmed during Trump’s first term in office. Said Sen. Lindsey Graham, R-S.C., about Hegseth: “Anonymous accusations are trying to destroy reputations again. We saw this with Kavanaugh. I won’t stand for it.” One widely watched Republican, Sen. Joni of Iowa, herself a former Army National Guard lieutenant colonel and sexual assault survivor who had been criticized by Trump allies for her cool reception to Hegseth, appeared more open to him after their follow-up meeting Monday. “I appreciate Pete Hegseth’s responsiveness and respect for the process,” Ernst said in a statement. Ernst said that following “encouraging conversations,” he had committed to selecting a senior official who will “prioritize and strengthen my work to prevent sexual assault within the ranks. As I support Pete through this process, I look forward to a fair hearing based on truth, not anonymous sources.” Ernst also had praise for Patel — “He shares my passion for shaking up federal agencies” — and for Gabbard. Once a rising Democratic star, Gabbard, who represented Hawaii in Congress, arrived a decade ago in Washington, her surfboard in tow, a new generation of potential leaders. She ran unsuccessfully for president in 2020. But Gabbard abruptly left the party and briefly became an independent before joining with Trump’s 2024 campaign as one of his enthusiasts, in large part over his disdain for U.S. involvement overseas and opposition to helping Ukraine battle Russia. Her visit to Syria to meet with then-President Bashar Assad around the time of Trump’s first inauguration during the country’s bloody civil war stunned her former colleagues and the Washington national security establishment. The U.S. had severed diplomatic relations with Syria. Her visit was seen by some as legitimizing a brutal leader who was accused of war crimes. Gabbard has defended the trip, saying it’s important to open dialogue, but critics hear in her commentary echoes of Russia-fueled talking points. Assad fled to Moscow over the weekend after Islamist rebels overtook Syria in a surprise attack, ending his family’s five decades of rule. She said her own views have been shaped by “my multiple deployments and seeing firsthand the cost of war and the threat of Islamist terrorism.” Gabbard said, “It’s one of the many reasons why I appreciate President Trump’s leadership and his election, where he is fully committed, as he has said over and over, to bring about an end to wars.” Last week, the nearly 100 former officials, who served in both Democratic and Republican administrations, said in the letter to Senate leaders they were “alarmed” by the choice of Gabbard to oversee all 18 U.S. intelligence agencies. They said her past actions “call into question her ability to deliver unbiased intelligence briefings to the President, Congress, and to the entire national security apparatus.” The Office of the Director of National Intelligence was created after the Sept. 11, 2001, attacks to coordinate the nation’s intelligence agencies and act as the president’s main intelligence adviser.

Hurricanes visit the Panthers in Eastern Conference action