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slots game free bonus no deposit As part of a national “moonshot” to cure blindness, researchers at the CU Anschutz Medical Campus will receive as much as $46 million in federal funding over the next five years to pursue a first-of-its-kind full eye transplantation. “This is no easy undertaking, but I believe we can achieve this together,” said Dr. Kia Washington, the lead researcher for the University of Colorado-led team, during a press conference Monday. “And in fact I’ve never been more hopeful that a cure for blindness is within reach.” The CU team was one of four in the United States that received funding awards from the federal Advanced Research Projects Agency for Health , or ARPA-H. The CU-based group will focus on achieving the first-ever vision-restoring eye transplant by using “novel stem cell and bioelectronic technologies,” according to a news release announcing the funding. The work will be interdisciplinary, Washington and others said, and will link together researchers at institutions across the country. The four teams that received the funding will work alongside each other on distinct approaches, though officials said the teams would likely collaborate and eventually may merge depending on which research avenues show the most promise toward achieving the ultimate goal of transplanting an eye and curing blindness. Dr. Calvin Roberts, who will oversee the broader project for ARPA-H, said the agency wanted to take multiple “shots on goal” to ensure progress. “In the broader picture, achieving this would be probably the most monumental task in medicine within the last several decades,” said Dr. Daniel Pelaez of the University of Miami’s Bascom Palmer Eye Institute, which also received ARPA-H funding. Pelaez is the lead investigator for that team, which has pursued new procedures to successfully remove and preserve eyes from donors, amid other research. He told The Denver Post that only four organ systems have not been successfully transplanted: the inner ear, the brain, the spinal cord and the eye. All four are part of the central nervous system, which does not repair itself when damaged. If researchers can successfully transplant the human eye and restore vision to the patient, it might help unlock deeper discoveries about repairing damage to the brain and spine, Pelaez said, as well as addressing hearing loss. To succeed, researchers must successfully remove and preserve eyes from donors and then successfully connect and repair the optical nerve, which takes information from the eye and tells the brain what the eye sees. A team at New York University performed a full eye transplant on a human patient in November 2023, though the procedure — while a “remarkable achievement,” Pelaez said — did not restore the patient’s vision. It was also part of a partial face transplant; other approaches pursued via the ARPA-H funding will involve eye-specific transplants. Washington, the lead CU researcher, said she and her colleagues have already completed the eye transplant procedure — albeit without vision restoration — in rats. The CU team will next work on large animals to advance “optic nerve regenerative strategies,” the school said, as well as to study immunosuppression, which is critical to ensuring that patients’ immune systems don’t reject a donated organ. The goal is to eventually advance to human trials. Pelaez and his colleagues have completed their eye-removal procedure in cadavers, he said, and they’ve also studied regeneration in several animals that are capable of regenerating parts of their eyes, like salamanders or zebra fish. His team’s funding will focus in part on a life-support machine for the eye to keep it healthy and viable during the removal process. InGel Therapeutics, a Massachusetts-based Harvard spinoff and the lead of a third team, will pursue research on 3-D printed technology and “micro-tunneled scaffolds” that carry certain types of stem cells as part of a focus on optical nerve regeneration and repair, ARPA-H said. ARPH-A, created two years ago, will oversee the teams’ work. Researchers at 52 institutions nationwide will also contribute to the teams. The CU-led group will include researchers from the University of Southern California, the University of Wisconsin, Indiana University and Johns Hopkins University, as well as from the National Eye Institute . The teams will simultaneously compete and collaborate: Pelaez said his team has communicated with researchers at CU and at Stanford, another award recipient, about their eye-removal research. The total funding available for the teams is $125 million, ARPA-H officials said Monday, and it will be distributed in phases, in part dependent on teams’ success. U.S. Rep. Diana DeGette, a Democrat who represents Denver in Congress, acknowledged the recent election results at the press conference Monday and pledged to continue fighting to preserve ARPA-H’s funding under President-elect Donald Trump’s administration. The effort to cure blindness, Washington joked, was “biblical” in its enormity — a reference to the Bible story in which Jesus cures a blind man. She and others also likened it to a moonshot, meaning the effort to successfully put Neil Armstrong and Buzz Aldrin on the moon nearly 50 years ago. If curing blindness is similar to landing on the moon, then the space shuttle has already left the launchpad, Washington said. “We have launched,” she said, “and we are on our trajectory.”None

Nexgel director Jerome Zeldis buys common stock worth $9,999Steep price hikes could be on the way if President-elect Donald Trump follows through on his pledge to impose sweeping new tariffs on imports from Mexico, Canada and China. He threatened to implement the tariffs on the country’s top three trading partners on his first day back in office, including a 10% tariff on products from China. In a pair of social media posts, he explained the decision as a way to crack down on illegal immigration and drugs. “On January 20th, as one of my many first Executive Orders, I will sign all necessary documents to charge Mexico and Canada a 25% Tariff on ALL products coming into the United States,” he said. “It is time for them to pay a very big price!” Ultimately, consumers could end up absorbing the brunt of those costs. When tariffs are levied on imports, American companies have to pay taxes to the U.S. government on their purchases from other countries; the companies often pass on those extra costs to customers. “This is a bully effort to put everybody on notice,” said economist Chris Thornberg, founding partner of Beacon Economics in Los Angeles. “One of the reasons he uses tariffs is because it’s one of the few places that he actually has some leverage.” Though Thornberg noted it’s still a “giant remains-to-be seen” whether and how Trump’s proposed tariffs are implemented, consumer goods across the board could be dramatically affected. Here are a few top categories: Mexico was the U.S.’s top goods trading partner last year, surpassing China. Mexico is a major manufacturer of passenger vehicles, light vehicles, trucks, auto parts, supplies and electric-vehicle technologies. Eighty-eight percent of vehicles produced there are exported, with 76% headed for the U.S., the International Trade Administration says. Automakers with manufacturing operations in Mexico include General Motors, Ford, Tesla, Audi, BMW, Honda, Kia, Mercedes Benz, Nissan, Toyota and Volkswagen. “If we get tariffs, we will pass those tariff costs back to the consumer,” Phil Daniele, chief executive of AutoZone, said in the company’s most recent earnings call. “We’ll generally raise prices ahead of ... what the tariffs will be.” Last year, China accounted for 77% of toy imports — about 25 times greater than the total value of toy imports from Mexico, the next largest foreign source of supply, according to the National Retail Federation. U.S. producers account for less than 1% of the toy market. The federation recently released a study that found the tariffs Trump proposed during his campaign — a universal 10% to 20% tariff on imports from all foreign countries and an additional 60% to 100% tariff on imports specifically from China — would apply to a wide range of toys imported into the U.S., including dolls, games and tricycles. “Prices of toys would increase by 36% to 56%,” the study concluded. The National Retail Federation study also analyzed more than 500 items of clothing and found prices “would rise significantly” — as much as 20.6%. That would force consumers to pare spending on apparel. Low-income households would be hit especially hard, the group said, because they spend three times as much of their after-tax income on apparel compared with high-income households. “U.S. apparel manufacturers would benefit from the tariffs, but at a high cost to families,” the study said. “Even after accounting for domestic manufacturing gains and new tariff revenue, the result is a net $16 billion to $18 billion loss for the U.S. economy, with the burden carried by U.S. consumers.” Imported footwear products already face high U.S. duties, particularly those made in China. The Footwear Distributors and Retailers of America expressed concern that new tariffs would make it more difficult for consumers to afford shoes and other everyday essentials. Trump’s proposed tariffs would increase the costs of several imported fruits and vegetables, said Jerry Nickelsburg, faculty director of UCLA Anderson Forecast, an economic forecasting organization. The vast majority of U.S. produce imports come from Mexico and Canada, including avocados, cucumbers, potatoes and mushrooms. The U.S. spent $88 billion on agricultural imports from the two countries in fiscal year 2024. Big-ticket electronic products such as televisions, laptops, smartphones, dishwashers and washing machines — many of which are manufactured in Mexico and China, or made with parts imported from those countries — likely would become more expensive. The U.S. imported $76 billion worth of computers and other electronics from Mexico in 2023, and more than a quarter of U.S. imports from China consist of electronic equipment.

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The Michigan Wolverines shocked the No. 2 Ohio State Buckeyes on Saturday, upsetting their rival 13-10 at Ohio Stadium in Columbus. Although Michigan entered the game just 6-5 on the season, head coach Sherrone Moore shut down the high-powered OSU offense, thus handing the Buckeyes their second loss of the campaign. Michigan authored an 11-play, 57-yard scoring drive that took 5:28 off the clock and put the Wolverines on top with a 21-yard field goal by Dominic Zvada with 45 seconds remaining. A 27-yard run by Michigan running back Kalel Mullings was the play of the game, as it helped put the Wolverines in field goal range: The Michigan defense stiffened once again on the ensuing drive, forcing a turnover on downs to preserve the massive upset. With the win, the Wolverines have now been victorious in the historic rivalry known as "The Game" in four straight seasons, marking their longest winning streak since taking four in a row over Ohio State from 1988 to 1991. Given the struggles of the OSU offense on Saturday, head coach Ryan Day and offensive coordinator Chip Kelly were widely criticized on social media: Ohio State attempted to establish the run throughout the game to no avail, as the team rushed for just 77 yards. Quarterback Will Howard struggled in his own right, going 19-of-33 for 175 yards with one touchdown and two interceptions. Overall, the Wolverines held Ohio State to 252 total yards, and they managed to win the game despite quarterback Davis Warren going just 9-of-16 for 62 yards with no touchdowns and two interceptions. With Saturday's loss, the Buckeyes are likely out of the Big Ten Championship Game. Undefeated Oregon has already clinched a spot in the game, meaning a win by either Penn State or Indiana on Saturday will knock OSU out. While Ohio State is not guaranteed a spot in the College Football Playoff after its second loss of the season, it is somewhat difficult to envision the Buckeyes going from No. 2 in the CFP standings to outside the top 12. However, even if the Buckeyes are part of the 12-team CFP field, many expressed their belief on social media that they are a fraud incapable of challenging for a national championship: After perhaps the most embarrassing loss of the Ryan Day era, Ohio State must now sit, wait and hope that it is granted a spot in the College Football Playoff and a chance to play for the national title. Even if that does happen, the Buckeyes will face a tough road since their chance at a first-round bye is now gone. As for the Wolverines, they have struggled through a tough season after going undefeated and winning it all last season, but they got head coach Sherrone Moore his signature win on Saturday. Although Michigan won't play in a significant bowl due to a 7-5 record, beating Ohio State still made it a worthwhile season for the program, and it provides the Wolverines with a huge building block for next season.The Green Party is set to suffer significant losses in the Irish General Election, with its leader expecting just a handful of parliamentarians to be returned. Children’s Minister Roderic O’Gorman said the party could not buck the trend in Ireland of junior coalition partners in Fine Gael and Fianna Fail governments losing support in subsequent elections. He said they expected to retain two to three seats out of the 12 they had won in the 2020 election on the back of a worldwide “Green wave”. “Undoubtedly it’s a disappointing result for our party today,” Mr O’Gorman told reporters in Ongar, Dublin. “It’s hard for a smaller party in government, that’s long been the tradition, the history in Ireland. We hoped going into the election to buck that but we haven’t been able to buck that today.” Mr O’Gorman, a candidate in Dublin West, is among the outgoing Green Party TDs in a battle to retain their seats. Culture Minister Catherine Martin, who is fighting to remain a Green Party TD for Dublin Rathdown, said it was a “very tight” race in her four-seat constituency. “We go in (to government) not afraid of that because the issue of the climate and biodiversity crisis is (greater) than our survival,” she said on RTE Radio. “I stand over and am proud of our track record of delivery.” Green candidate in Waterford Marc O Cathasaigh said he would not be “in the shake-up” to retain his seat in that constituency, while junior minister Ossian Smyth looks at risk of losing his seat in Dun Laoghaire. Junior minister Joe O’Brien is expected to lose his seat in Dublin Fingal, Neasa Hourigan is at risk in Dublin Central, while Wicklow’s Steven Matthews garnered just 4% of first preferences. Former Green Party leader Eamon Ryan, who announced his retirement from frontline politics in June, said his party had not had a good day. Arriving at the count centre at the RDS in Dublin, the outgoing environment minister told reporters: “If you don’t get elected you accept that, but you come back stronger and you learn lessons, and we’ve done that in the past and we will do that again.” He added: “No matter what the results today there will be a strong Green Party in Ireland, we have deep roots in the community and it’s a very distinct political philosophy and I think there is still space for that in Irish politics, for sure.” Mr Ryan said he did not believe his decision to retire, and the timing of his announcement, had affected the party’s showing. “Unfortunately – and this is just one of those days – we didn’t get the number of votes,” he said. He added: “We’ll look back and see what are the lessons, and what can we learn and what can we do differently. “It’s just one of those days when we didn’t have a good day.SAN DIEGO, Dec. 03, 2024 (GLOBE NEWSWIRE) -- Fate Therapeutics, Inc. (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune diseases, today announced that on December 2, 2024 the Company granted restricted stock units (RSUs) representing 18,600 shares of its common stock to one newly-hired non-executive employee. The grant was approved by the Compensation Committee of the Company’s Board of Directors and granted under the Company’s Amended and Restated Inducement Equity Plan as an inducement material to the new employee entering into employment with the Company in accordance with Nasdaq Listing Rule 5635(c)(4). The RSUs will vest over four years, with 25% of the shares underlying each RSU award vesting on each anniversary of the grant date, subject to the employee being continuously employed by the Company through each vesting date. About Fate Therapeutics, Inc. Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune diseases. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s pipeline includes iPSC-derived natural killer (NK) cell and T-cell product candidates, which are selectively designed, incorporate novel synthetic controls of cell function, and are intended to deliver multiple therapeutic mechanisms to patients. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com . Contact: Christina Tartaglia Precision AQ 212.362.1200 christina.tartaglia@precisionaq.comSteve Granitz/FilmMagic; Monica Schipper/Getty is answering fans’ burning question about the Thanksgiving episode. In an interview with Walter addressed why didn’t play her mother on the ABC sitcom after the actress asked for the role on her social media in earlier this year. The comedian, 61, revealed that logistics got in the way, leading to being cast instead. “There had been so much discussion around it because of the whole thing with Bette Midler,” she began. “And when it wasn’t going to work out because of scheduling, they said they were talking about a couple of people and Talia was one of them.” Walter recalled getting emotional at the thought of working with Shire, saying, “Literally, tears burst into my eyes. Isn’t that bizarre? said, ‘We’re talking to Talia Shire,’ and tears burst out of my eyes. I said, ‘I don’t know why I did that. I feel ridiculous. But she’s royalty,’ and Quinta just said, ‘She is.’” Michael Buckner/Variety via Getty; Jon Kopaloff/Getty Growing up, Walter said she and her family would watch on Thanksgiving, and later, in which Shire starred as Connie Corleone. “When my mother was alive, we would put on the way we watch at Christmas, just 24 hours of it,” Walter shared. “And I know that for Philly people, obviously, it’s the connection, but for my household, it was always and just the evolution of her acting over the years and how we always saw her as being kind of this little meek young woman and then she becomes powerful, I think it’s such a beautiful acting trajectory that she’s had in her career and she’s lovely to work with.” Related: In April, Midler, 79, joked on X (formerly Twitter) about wanting to join when she took the opportunity to name more parts she hoped to get. "Since I'm now using this website to pitch myself on TV shows, I would also like to play Melissa Schemmenti's mother on ," Middler wrote on her since-deleted account, adding: "If you see Quinta Brunson, please tell her." Bruce Glikas/WireImage Midler has worked with stars in the past and opened up about her friendship with , who plays kindergarten teacher Barbara Howard in the series, in July. The pair filmed the recent film together and “really bonded” over their roots in performing for a live audience, Midler . “We both come from the stage. I've been a fan of hers for a long, long time, ever since ,” Midler said, referring to Ralph’s turn as Deena Jones in the original 1981 production of the Henry Krieger and Tom Eyen musical about the breakup of a 1960s girl group. Ralph also appeared in shows and . Season 4 of premieres Wednesday, Jan. 8, moving to an 8:30 p.m. time slot and streaming the next day on Hulu. Read the original article on

Activists say Montreal pro-Palestinian protests have been over-policed‘We didn’t have a good day’: Greens set to suffer significant election losses

The leader of Sinn Fein has expressed determination to form a government of the left in Ireland as she insisted her party’s performance in the General Election had broken the state’s political mould. Despite Mary Lou McDonald’s confidence around shaping a coalition without Fine Gael and Fianna Fail – the two parties that have dominated the landscape of Irish politics for a century – the pathway to government for Sinn Fein still appears challenging. With counting following Friday’s election still in the relatively early stages – after an exit poll that showed the main three parties effectively neck-and-neck – there is some way to go before the final picture emerges and the options for government formation crystalise. Taoiseach and Fine Gael leader, Simon Harris, has dismissed talk of a Sinn Fein surge and said he was “cautiously optimistic” about where his party will stand after all the votes are counted. Meanwhile, Ireland’s deputy premier and Fianna Fail leader, Micheal Martin , insisted his party has a “very clear route back to government” as he predicted seat gains. The counting process could last days because of Ireland’s complex system of proportional representation with a single transferable vote (PR-STV), where candidates are ranked by preference. The early indications have turned the focus to the tricky arithmetic of government formation, as the country’s several smaller parties and many independents potentially jockey for a place in government. Ms McDonald told reporters at the RDS count centre in Dublin that she would be “very, very actively pursuing” the potential to form a government with other parties on the left of the political spectrum. The smaller, left-leaning parties in Ireland include the Social Democrats, the Irish Labour Party, the Green Party and People Before Profit-Solidarity. Ms McDonald said her party had delivered an “incredible performance” in the election. “I think it’s fair to say that we have now confirmed that we have broken the political mould here in this state,” she said. “Two party politics is now gone. It’s consigned to the dustbin of history and that, in itself, is very significant.” She added: “I am looking to bring about a government of change, and I’m going to go and look at all formulations. “If you want my bottom line, the idea of Fianna Fail and Fine Gael for another five years, in our strong opinion, is not a good outcome for Irish society. “Obviously, I want to talk to other parties of the left and those that we share very significant policy objectives with. So I’m going to do that first and just hear their mind, hear their thinking. But be very clear, we will be very, very actively pursuing entrance into government.” In Friday night’s exit poll, Sinn Fein was predicted to take 21.1% of first-preference votes, narrowly ahead of outgoing coalition partners Fine Gael and Fianna Fail at 21% and 19.5% respectively. Prior to the election, Fianna Fail and Fine Gael both ruled out entering government with Sinn Fein. Fine Gael leader Mr Harris rejected suggestions Sinn Fein had broken new ground. He told reporters in his count centre in Greystones, Co Wicklow: “Certainly we haven’t seen a Sinn Fein surge or anything like it. “I mean, it looks likely, on the figures that we’ve seen now, fewer people, many fewer people would have voted Sinn Fein in this election than the last one. “In fact, I think they’re down by around 5% and actually the parties, particularly the two parties, the two larger parties in government, are likely to receive significant support from the electorate. So definitely, politics in Ireland has gotten much more fragmented.” He said it was too early to tell what the next government would look like. “I think anybody who makes any suggestion about who is going to be the largest party or the construct of the next government, they’re a braver person than I am,” he said. “Our electoral system dictates that there’ll be many, many transfers that will go on for hours, if not days, before we know the final computations at all. “But what I am very confident about is that my party will have a very significant role to play in the years ahead, and I’m cautiously optimistic and excited.” Fianna Fail’s Mr Martin told reporters at a count centre in Cork he was confident that the numbers exist to form a government with parties that shared his political viewpoint. Mr Martin said it “remains to be seen” whether he would return to the role of Taoiseach – a position he held between 2020 and 2022 – but he expressed confidence his party would outperform the exit poll prediction. “It’s a bit too early yet to call the exact type of government that will be formed or the composition of the next government,” he said. “But I think there are, there will be a sufficiency of seats, it seems to me, that aligns with the core principles that I articulated at the outset of this campaign and throughout the campaign, around the pro-enterprise economy, around a positively pro-European position, a government that will strongly push for home ownership and around parties that are transparently democratic in how they conduct their affairs.” Asked if it would be in a coalition with Fianna Fail, Fine Gael and the Social Democrats, he said that would be “racing a bit too far ahead”. The final result may dictate that if Fianna Fail and Fine Gael are to return to government, they may need more than one junior partner, or potentially the buy-in of several independent TDs. Mr Martin said it was unclear how quickly a government can be formed, as he predicted his party would gain new seats. “It will be challenging. This is not easy,” he added. The junior partner in the outgoing government – the Green Party – looks set for a bruising set of results. Green leader Roderic O’Gorman is in a fight to hold onto his seat, as are a number of party colleagues, including Media Minister Catherine Martin. “It’s clear the Green Party has not had a good day,” he said. The early counting also suggested potential trouble for Fianna Fail in Wicklow, where the party’s only candidate in the constituency, Health Minister Stephen Donnelly, is considered to have a battle ahead, with the risk of losing his seat. Meanwhile, there is significant focus on independent candidate Gerard Hutch who, on Saturday evening, was sitting in fourth place in the four-seat constituency of Dublin Central. Last spring, Mr Hutch was found not guilty by the non-jury Special Criminal Court of the murder of David Byrne, in one of the first deadly attacks of the Hutch-Kinahan gangland feud. Mr Byrne, 33, died after being shot six times at a crowded boxing weigh-in event at the Regency Hotel in February 2016. A Special Criminal Court judge described Mr Hutch, 61, as the patriarchal figurehead of the Hutch criminal organisation and said he had engaged in “serious criminal conduct”. The constituency will be closely watched as other hopefuls wait to see if transfers from eliminated candidates may eventually rule him out of contention. In the constituency of Louth, the much-criticised selection of John McGahon appeared not to have paid off for Fine Gael. The party’s campaign was beset by questioning over footage entering the public domain of the candidate engaged in a fight outside a pub in 2018. The Social Democrats have a strong chance of emerging as the largest of the smaller parties. The party’s leader, Holly Cairns, was already celebrating before a single vote was counted however, having announced the birth of her baby girl on polling day.NoneWhat people read on Wikipedia in 2024

Amazon Cyber Monday deals LIVE: 101+ sales I’m shopping on TVs, laptops, Switch and moreAs part of a national “moonshot” to cure blindness, researchers at the CU Anschutz Medical Campus will receive as much as $46 million in federal funding over the next five years to pursue a first-of-its-kind full eye transplantation. “This is no easy undertaking, but I believe we can achieve this together,” said Dr. Kia Washington, the lead researcher for the University of Colorado-led team, during a press conference Monday. “And in fact I’ve never been more hopeful that a cure for blindness is within reach.” The CU team was one of four in the United States that received funding awards from the federal Advanced Research Projects Agency for Health , or ARPA-H. The CU-based group will focus on achieving the first-ever vision-restoring eye transplant by using “novel stem cell and bioelectronic technologies,” according to a news release announcing the funding. The work will be interdisciplinary, Washington and others said, and will link together researchers at institutions across the country. The four teams that received the funding will work alongside each other on distinct approaches, though officials said the teams would likely collaborate and eventually may merge depending on which research avenues show the most promise toward achieving the ultimate goal of transplanting an eye and curing blindness. Dr. Calvin Roberts, who will oversee the broader project for ARPA-H, said the agency wanted to take multiple “shots on goal” to ensure progress. “In the broader picture, achieving this would be probably the most monumental task in medicine within the last several decades,” said Dr. Daniel Pelaez of the University of Miami’s Bascom Palmer Eye Institute, which also received ARPA-H funding. Pelaez is the lead investigator for that team, which has pursued new procedures to successfully remove and preserve eyes from donors, amid other research. He told The Denver Post that only four organ systems have not been successfully transplanted: the inner ear, the brain, the spinal cord and the eye. All four are part of the central nervous system, which does not repair itself when damaged. If researchers can successfully transplant the human eye and restore vision to the patient, it might help unlock deeper discoveries about repairing damage to the brain and spine, Pelaez said, as well as addressing hearing loss. To succeed, researchers must successfully remove and preserve eyes from donors and then successfully connect and repair the optical nerve, which takes information from the eye and tells the brain what the eye sees. A team at New York University performed a full eye transplant on a human patient in November 2023, though the procedure — while a “remarkable achievement,” Pelaez said — did not restore the patient’s vision. It was also part of a partial face transplant; other approaches pursued via the ARPA-H funding will involve eye-specific transplants. Washington, the lead CU researcher, said she and her colleagues have already completed the eye transplant procedure — albeit without vision restoration — in rats. The CU team will next work on large animals to advance “optic nerve regenerative strategies,” the school said, as well as to study immunosuppression, which is critical to ensuring that patients’ immune systems don’t reject a donated organ. The goal is to eventually advance to human trials. Pelaez and his colleagues have completed their eye-removal procedure in cadavers, he said, and they’ve also studied regeneration in several animals that are capable of regenerating parts of their eyes, like salamanders or zebra fish. His team’s funding will focus in part on a life-support machine for the eye to keep it healthy and viable during the removal process. InGel Therapeutics, a Massachusetts-based Harvard spinoff and the lead of a third team, will pursue research on 3-D printed technology and “micro-tunneled scaffolds” that carry certain types of stem cells as part of a focus on optical nerve regeneration and repair, ARPA-H said. ARPH-A, created two years ago, will oversee the teams’ work. Researchers at 52 institutions nationwide will also contribute to the teams. The CU-led group will include researchers from the University of Southern California, the University of Wisconsin, Indiana University and Johns Hopkins University, as well as from the National Eye Institute . The teams will simultaneously compete and collaborate: Pelaez said his team has communicated with researchers at CU and at Stanford, another award recipient, about their eye-removal research. The total funding available for the teams is $125 million, ARPA-H officials said Monday, and it will be distributed in phases, in part dependent on teams’ success. U.S. Rep. Diana DeGette, a Democrat who represents Denver in Congress, acknowledged the recent election results at the press conference Monday and pledged to continue fighting to preserve ARPA-H’s funding under President-elect Donald Trump’s administration. The effort to cure blindness, Washington joked, was “biblical” in its enormity — a reference to the Bible story in which Jesus cures a blind man. She and others also likened it to a moonshot, meaning the effort to successfully put Neil Armstrong and Buzz Aldrin on the moon nearly 50 years ago. If curing blindness is similar to landing on the moon, then the space shuttle has already left the launchpad, Washington said. “We have launched,” she said, “and we are on our trajectory.”

TULSA, Okla. (AP) — Michael Jacobs' 19 points off of the bench helped lead Southern to a 70-66 victory over Tulsa on Saturday. Read this article for free: Already have an account? To continue reading, please subscribe: * TULSA, Okla. (AP) — Michael Jacobs' 19 points off of the bench helped lead Southern to a 70-66 victory over Tulsa on Saturday. Read unlimited articles for free today: Already have an account? TULSA, Okla. (AP) — Michael Jacobs’ 19 points off of the bench helped lead Southern to a 70-66 victory over Tulsa on Saturday. Jacobs shot 7 of 15 from the field and 5 of 5 from the free-throw line for the Jaguars (4-4). Cam Amboree added 10 points while going 3 of 5 (2 for 3 from 3-point range) while they also had five rebounds. Derrick Tezeno shot 4 of 6 from the field to finish with 10 points. The Golden Hurricane (4-6) were led by Keaston Willis, who recorded 23 points and seven rebounds. Tyshawn Archie added 17 points, four assists and two blocks for Tulsa. Ian Smikle also had 11 points and eight rebounds. ___ The Associated Press created this story using technology provided by Data Skrive and data from Sportradar. AdvertisementResearchers launch “moonshot” to cure blindness through eye transplants

Thousands of pro-EU protesters march on Georgia parliamentIncoming City Council President Joe LaCava said he is “neutral” on efforts by some La Jolla residents to create a separate city, but pointed out that it would be very difficult to accomplish. “I have chosen to remain neutral because clearly La Jollans are looking for someone who can give them objective answers,” he said when the question was asked during a press conference on Tuesday. LaCava represents District 1 , which stretches from Pacific Beach through Carmel Valley to Pacific Highlands Ranch, and noted that his own residence would be in the separate city proposed by The Association for the City of La Jolla , a nonprofit group. He acknowledged that new cities have incorporated in San Diego County in recent years, citing Encinitas and Santee, but noted that seceding from an existing city is much harder. “In the state of California only one community has successfully detached from another city, and that was Coronado in the 1800s. That speaks to the challenge,” LaCava said. We have launched our year-end campaign. Our goal: Raise $50,000 by Dec. 31. Help us get there. Times of San Diego is devoted to producing timely, comprehensive news about San Diego County. Your donation helps keep our work free-to-read, funds reporters who cover local issues and allows us to write stories that hold public officials accountable. Join the growing list of donors investing in our community's long-term future. On its website, the La Jolla association claims residents of the wealthy area would benefit from improved roads, greater safety, prioritization of local projects and having a voice in Sacramento. The proposed city boundaries would be largely based on the 92037 Zip Code but not include UC San Diego. “It’s a small group that has brought this forward.. They go under the tag line, if I’m not mistaken, of ‘imagine,'” said LaCava. “To run a city takes more than just ‘imagine.’ There are a lot of details that have to be worked out.” Seceding from San Diego would require voters in both La Jolla and the rest of the city to approve the separation. Volunteers have been collecting signatures to petition the Local Agency Formation Commission to study the feasibility of a separate city of La Jolla, one of the steps required before a vote is possible. Get Our Free Daily Email Newsletter Get the latest local and California news from Times of San Diego delivered to your inbox at 8 a.m. daily. Sign up for our free email newsletter and be fully informed of the most important developments.