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ST Picks: The growing draw of ‘iron rice bowls’ for China’s young peopleNone
Ramstad: Murder of UnitedHealth exec incites anger — not at the killer, but at him and the company
NoneDuring the forum, participants engaged in extensive discussions on a wide range of topics, including economic cooperation, cultural exchanges, social development, and political collaboration. One of the key highlights of the forum was the emphasis on the importance of promoting dialogue and understanding between political parties from China and Latin America. By fostering better communication and coordination, both regions can work together more effectively towards common goals and shared interests.
Unveiling the HarmonyOS on Huawei Pura 70 Series: More Than Just Price Surprises on Double 12Liverpool boss Arne Slot talks up ‘special player’ Mohamed SalahThe incident unfolded on a tranquil morning as the villagers went about their daily routines. A group of farmers had ventured into the dense forest to graze their cattle when they stumbled upon the wounded animal, its fur matted with blood and deep claw marks etched into its flesh. Fear and uncertainty gripped the villagers as they realized the potential threat that lurked in their midst.
Even with access to blockbuster obesity drugs, some people don't lose weight Unlike scores of people who scrambled for the blockbuster drugs Ozempic and Wegovy to lose weight in recent years, Danielle Griffin had no trouble getting them. The 38-year-old information technology worker from New Mexico had a prescription. Jonel Aleccia, The Associated Press Nov 23, 2024 6:10 AM Share by Email Share on Facebook Share on X Share on LinkedIn Print Share via Text Message FILE - Donna Cooper holds up a dosage of Wegovy, a drug used for weight loss, at her home, March 1, 2024, in Front Royal, Va. (AP Photo/Amanda Andrade-Rhoades, File) Unlike scores of people who scrambled for the blockbuster drugs Ozempic and Wegovy to lose weight in recent years, Danielle Griffin had no trouble getting them. The 38-year-old information technology worker from New Mexico had a prescription. Her pharmacy had the drugs in stock. And her health insurance covered all but $25 to $50 of the monthly cost. For Griffin, the hardest part of using the new drugs wasn’t access. It was finding out that the much-hyped medications didn’t really work for her. “I have been on Wegovy for a year and a half and have only lost 13 pounds,” said Griffin, who watches her diet, drinks plenty of water and exercises regularly. “I’ve done everything right with no success. It’s discouraging.” In clinical trials, most participants taking Wegovy or Mounjaro to treat obesity lost an average of 15% to 22% of their body weight — up to 50 pounds or more in many cases. But roughly 10% to 15% of patients in those trials were “nonresponders” who lost less than 5% of their body weight. Now that millions of people have used the drugs, several obesity experts told The Associated Press that perhaps 20% of patients — as many as 1 in 5 — may not respond well to the medications. It's a little-known consequence of the obesity drug boom, according to doctors who caution eager patients not to expect one-size-fits-all results. “It's all about explaining that different people have different responses,” said Dr. Fatima Cody Stanford, an obesity expert at Massachusetts General Hospital The drugs are known as GLP-1 receptor agonists because they mimic a hormone in the body known as glucagon-like peptide 1. Genetics, hormones and variability in how the brain regulates energy can all influence weight — and a person's response to the drugs, Stanford said. Medical conditions such as sleep apnea can prevent weight loss, as can certain common medications, such as antidepressants, steroids and contraceptives. “This is a disease that stems from the brain,” said Stanford. “The dysfunction may not be the same” from patient to patient. Despite such cautions, patients are often upset when they start getting the weekly injections but the numbers on the scale barely budge. “It can be devastating,” said Dr. Katherine Saunders, an obesity expert at Weill Cornell Medicine and co-founder of the obesity treatment company FlyteHealth. “With such high expectations, there’s so much room for disappointment.” That was the case for Griffin, who has battled obesity since childhood and hoped to shed 70 pounds using Wegovy. The drug helped reduce her appetite and lowered her risk of diabetes, but she saw little change in weight. “It’s an emotional roller coaster,” she said. “You want it to work like it does for everybody else.” The medications are typically prescribed along with eating behavior and lifestyle changes. It’s usually clear within weeks whether someone will respond to the drugs, said Dr. Jody Dushay, an endocrine specialist at Beth Israel Deaconess Medical Center. Weight loss typically begins right away and continues as the dosage increases. For some patients, that just doesn't happen. For others, side effects such as nausea, vomiting and diarrhea force them to halt the medications, Dushay said. In such situations, patients who were counting on the new drugs to pare pounds may think they’re out of options. “I tell them: It's not game over,” Dushay said. Trying a different version of the new class of drugs may help. Griffin, who didn't respond well to Wegovy, has started using Zepbound, which targets an additional hormone pathway in the body. After three months of using the drug, she has lost 7 pounds. “I'm hoping it's slow and steady,” she said. Other people respond well to older drugs, the experts said. Changing diet, exercise, sleep and stress habits can also have profound effects. Figuring out what works typically requires a doctor trained to treat obesity, Saunders noted. “Obesity is such a complex disease that really needs to be treated very comprehensively,” she said. “If what we’re prescribing doesn’t work, we always have a backup plan.” ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content. Jonel Aleccia, The Associated Press See a typo/mistake? Have a story/tip? This has been shared 0 times 0 Shares Share by Email Share on Facebook Share on X Share on LinkedIn Print Share via Text Message More The Mix UN talks in disarray as a rough draft deal for climate cash is rejected by developing nations Nov 23, 2024 6:15 AM These Peruvian women left the Amazon, but their homeland still inspires their songs and crafts Nov 23, 2024 5:43 AM Ottawa to deliver apology, $45M in compensation for Nunavik Inuit dog slaughter Nov 23, 2024 3:00 AM Featured FlyerTEMPE, Ariz. (AP) — Miguel Tomley scored 28 points as Weber State beat Pepperdine 68-53 in the Desert Division championship game of the Arizona Tip-Off on Saturday night. Tomley shot 7 for 12 (6 for 7 from 3-point range) and 8 of 8 from the free-throw line for the Wildcats (4-4). Blaise Threatt added 21 points and seven rebounds. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Get updates and player profiles ahead of Friday's high school games, plus a recap Saturday with stories, photos, video Frequency: Seasonal Twice a week
The foreign policy community back home fears Indonesian President Prabowo Subianto has given too much away to China in a departure from longstanding policy. It is not uncommon for new leaders, especially those who come through with strong mandates, to allow themselves to believe that their popularity with the home crowd can be ported across to the field of foreign relations in the quest to find solutions to thorny issues. President Rodrigo Duterte did so in his attempt to reset the Philippines’ relations with China, India’s Narendra Modi tried the same with Pakistan. But before long, wisdom dawns as the airborne trajectories of such ambitions are brought down to earth by the weight of national interests, the cautionary warnings of bureaucrats and their institutional memory, and the hard realities of global politics. Balance is restored. Already a subscriber? Log in Get exclusive reports and insights with more than 500 subscriber-only articles every month $9.90 $9.90/month No contract ST app access on 1 mobile device Subscribe now All subscriber-only content on ST app and straitstimes.com Easy access any time via ST app on 1 mobile device E-paper with 2-week archive so you won't miss out on content that matters to you Join ST's Telegram channel and get the latest breaking news delivered to you. Read 3 articles and stand to win rewards Spin the wheel nowUPDATE: Sheriff Honea identifies shooter, victims in Seventh-Day Adventist school shooting
PUMA Teams Up with Adam&EveDDB for Bold New Global Brand Strategy
Ultimately, the decision to adopt a linear narrative in the new "Four Seas Brothers" installment proves to be a bold and inspired choice. By streamlining the storytelling and focusing on the characters' journey in a more direct way, the filmmakers have reinvigorated the series and redefined the gangster film experience for audiences. As viewers immerse themselves in the world of the "Four Seas Brothers" once again, they will be treated to a compelling and emotionally resonant tale of brotherhood, betrayal, and redemption that stands as a testament to the enduring power of the gangster genre.
Nazanin Zaghari-Ratcliffe: I forgive but will not forget Johnson’s slip
Peavy's 24 help Georgetown beat Albany 100-68
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Aaron Ramsdale, the talented young goalkeeper who currently plays for Sheffield United, has been identified by Wright as the ideal candidate to strengthen Chelsea's defense. Ramsdale has been in impressive form this season, showcasing his shot-stopping abilities and command of the penalty area. At just 23 years old, he has already gained valuable experience in the Premier League and has the potential to develop into a top-class goalkeeper in the years to come.PHILADELPHIA , Dec. 19, 2024 /PRNewswire/ -- FMC Corporation (NYSE: FMC) announced today it will release its fourth quarter 2024 earnings on Tuesday, February 4, 2025 , after the stock market close via PR Newswire and the company's website https://investors.fmc.com . The company will host a webcast conference call on Tuesday, February 4, 2025 , at 5:00 p.m. ET that is open to the public via internet broadcast and telephone. At this time, management will provide commentary on the results from the fourth quarter and full year 2024, guidance for the first quarter and full year 2025, as well as an update on the three-year outlook and the company's strategy. The call time has been extended to 90 minutes from the usual 60 minutes to accommodate the number of topics and Q&A adequately. Conference Call Details: Internet broadcast: https://investors.fmc.com United States (Local): +1 404 975 4839 United States ( Toll-Free ): +1 833 470 1428 Global Dial-In Numbers: Global Dial-in Number Access Code: 338624 Pre-Registration Link: https://www.netroadshow.com/events/login?show=2f7e0221&confId=75596 A replay of the call will be available via the internet and telephone from 6:30 p.m. ET on February 4, 2025 , until February 24, 2025 . Internet replay: https://investors.fmc.com United States (Local): 1 929 458 6194 United States ( Toll-Free ): 1 866 813 9403 Access Code: 793208 About FMC FMC Corporation is a global agricultural sciences company dedicated to helping growers produce food, feed, fiber and fuel for an expanding world population while adapting to a changing environment. FMC's innovative crop protection solutions – including biologicals, crop nutrition, digital and precision agriculture – enable growers and crop advisers to address their toughest challenges economically while protecting the environment. With approximately 5,800 employees at more than 100 sites worldwide, FMC is committed to discovering new herbicide, insecticide and fungicide active ingredients, product formulations and pioneering technologies that are consistently better for the planet. Visit fmc.com to learn more and follow us on LinkedIn ® . View original content to download multimedia: https://www.prnewswire.com/news-releases/fmc-corporation-announces-date-for-fourth-quarter-2024-earnings-release-and-webcast-conference-call-302336288.html SOURCE FMC Corporation
Safety is also a top priority for Deep Blue, and the S09 comes equipped with a host of advanced features designed to keep you and your passengers safe on the road. From collision avoidance systems to lane departure warnings, this SUV is packed with cutting-edge technology that gives you peace of mind every time you get behind the wheel.Title: Foreign Ministry: Visa Restrictions Imposed on US Personnel Behaving Badly on Hong Kong Issues
