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roulette best strategy When it comes to figuring out what's about to be big before it totally explodes, the best search-it-out strategy we know tends to be something along the lines of: identify someone (or something) that always has a pulse on what's happening. Then pay attention. That's what makes watching the so genius. Since its launch, the global brand's in-network development pool has connected more than 4,600 creatives with the resources and audience to turn their designing dreams into reality. The fashion world can be tough, period—and pretty near impossible to break into when you consider how much the little fish have (like, IDK, established operational systems and fancy-schmancy distribution systems). SHEIN, the biggest fish in the ~biggest~ pond, created SHEIN X to help it be the fairy godmother to little guys. The program opens up the , huge fabric libraries, supply-chain technologies, and global reach to designers who are just starting to punch above their indie roots. What is SHEIN X? It's a designer's dream come true—a unique initiative by SHEIN that collaborates with creatives and brands. Imagine it as a fashion house presenting talents globally, offering fresh, exciting styles infused with the distinct flair of each designer, a true masterpiece. Why shop SHEIN X? If you're on the hunt for unique, one-of-a-kind pieces, SHEIN X is your go-to choice. It offers designer fashion at friendly prices, making it easy to shop exclusive, high-quality styles from emerging talents and renowned names you won't find elsewhere. That's not to say it's only working with small names, though. The program routinely connects with buzzy brands and artists in their own right from a variety of backgrounds—to bring their magic into the wardrobe world. For example, the brand has collaborated with Canadian digital artist , bespoke clothier , and (you know, the one with a cool 64 social followers?). New you-need-to-know names include , the Iowa-based designer behind BELANGE HANDMADE, who worked with SHEIN to trampoline her way into the stratosphere. Her signature look, bright and vibrant, was established ahead of the —but now it's just available to way, way more people. Dresses are the thing for , too. Southern California designer Lillian Love's label focuses on dresses: form-fitting knit silhouettes, cutouts, sparkles...you name it, it's there. A similar yet also super-unique look is the calling card for . Born and raised in Ohio, the current Angeleno has used her partnership with SHEIN X to make her dramatic-glam dresses more easily accessible to all of us (thank ya, Keshae!). Featuring swirls, curves, and cutouts, they have an optical-illusion quality that's almost impossible to look away from. The last name we want you to know is , a beautiful line made by Atlanta-based Bahamian artist Melissa A. Mitchell. If most of the SHEIN in your wardrobe includes clothes you'll wear out (whether to the office or after hours), this is your new vacation situation. And by that we mean stuff to wear when you're deplaning somewhere fabulous and sunny—but also in normal life when you just need a jolt of out-of-office energy. Why join SHEIN X? Breaking into fashion is tough, but SHEIN X kick-starts creators' journeys. From design support to global logistics, it equips emerging talent with the necessary tools to bring ideas to life and reach the world, while empowering established names with data analytics to scale production. The bottom style line is that the is a win-win: While it's helping to give emerging designers a major boost through its established resources and logistics, it's also bringing good newness into our own closets that emphasize originality, making upscale fashion accessible to everyone. Shopping brands most people haven't heard of, from your favorite easy-to-browse platform? Yep, you're about to be the best-dressed friend in your group.Lindsey is a Seattle area writer interested in all things society, including internet culture, politics, and mental health. Outside of the Daily Dot, her work can be found in publications such as The Mary Sue, Truthout, and YES! Magazine.NEW YORK (AP) — There's no place like home for the holidays. And that may not necessarily be a good thing. In the wake of the very contentious and divisive 2024 presidential election, the upcoming celebration of Thanksgiving and the ramp-up of the winter holiday season could be a boon for some — a respite from the events of the larger world in the gathering of family and loved ones. Hours and even days spent with people who have played the largest roles in our lives. Another chapter in a lifetime of memories. That's one scenario. For others, that same period — particularly because of the polarizing presidential campaign — is something to dread. There is the likelihood of disagreements, harsh words, hurt feelings and raised voices looming large. Those who make a study of people and their relationships to each other in an increasingly complex 21st-century say there are choices that those with potentially fraught personal situations can make — things to do and things to avoid — that could help them and their families get through this time with a minimum of open conflict and a chance at getting to the point of the holidays in the first place. For those who feel strongly about the election's outcome, and know that the people they would be spending the holiday feel just as strongly in the other direction, take the time to honestly assess if you're ready to spend time together in THIS moment, barely a few weeks after Election Day — and a time when feelings are still running high. The answer might be that you're not, and it might be better to take a temporary break, says Justin Jones-Fosu, author of “I Respectfully Disagree: How to Have Difficult Conversations in a Divided World.” “You have to assess your own readiness,” he says, “Each person is going be very different in this.” He emphasizes that it's not about taking a permanent step back. “Right now is that moment that we’re talking about because it’s still so fresh. Christmas may be different.” Keep focused on why why you decided to go in the first place, Jones-Fosu says. Maybe it’s because there’s a relative there you don’t get to see often, or a loved one is getting up in age, or your kids want to see their cousins. Keeping that reason in mind could help you get through the time. If you decide getting together is the way to go, but you know politics is still a dicey subject, set a goal of making the holiday a politics-free zone and stick with it, says Karl Pillemer, a professor at Cornell University whose work includes research on family estrangement. “Will a political conversation change anyone’s mind?" he says. “If there is no possibility of changing anyone’s mind, then create a demilitarized zone and don’t talk about it.” Let’s be honest. Sometimes, despite best efforts and intentions to keep the holiday gathering politics- and drama-free, there’s someone who’s got something to say and is going to say it. In that case, avoid getting drawn into it, says Tracy Hutchinson, a professor in the graduate clinical mental health counseling program at the College of William & Mary in Virginia. “Not to take the hook is one of the most important things, and it is challenging,” she says. After all, you don’t have to go to every argument you’re invited to. If you risk getting caught up in the moment, consider engaging in what Pillemer calls “forward mapping.” This involves thinking medium and long term rather than just about right now — strategy rather than tactics. Maybe imagine yourself six months from now looking back on the dinner and thinking about the memories you'd want to have. “Think about how you would like to remember this holiday,” he says. “Do you want to remember it with your brother and sister-in-law storming out and going home because you’ve had a two-hour argument?” Things getting intense? Defuse the situation. Walk away. And it doesn't have to be in a huff. Sometimes a calm and collected time out is just what you — and the family — might need. Says Hutchinson: “If they do start to do something like that, you could say, `I’ve got to make this phone call. I’ve got to go to the bathroom. I’m going to take a walk around the block.'"

There are a lot of conversations taking place these days around the incoming Donald Trump administration’s focus on bringing home jobs and investment to the US. If the election campaign rhetoric develops into concrete action, Ireland stands out as potentially one of the big losers over the next four years of US Republican rule. Ireland receives four times more investments from US corporations than the EU average as a percentage of the economy. In 2024, the US flow of investment into Ireland continued at pace. IDA Ireland announced that investment approvals in the first half of 2024 reached a record high, maintaining the upward trend from prior years, predominantly coming from US corporations. The prospect of a global trade war and Mr Trump’s proposal to slash corporation tax to 15% , allied to the possible targeting of the strong US investment in pharmaceutical and the information and communication technology sector based in Ireland, could have particular implications for continued investment here and for the associated and enormous tax receipts. The macro picture remains mired by volatility, uncertainty, complexity, and ambiguity, primarily associated with our extreme dependence on trade and investment with the US. Much of the risk could be reduced if we diversify our focus on foreign direct investment from the USA Diversifying the focus of foreign direct investment is overdue. Many think China, the second largest economy globally, is the obvious diversification option to pursue. There have been attempts by IDA Ireland to diversify having expanded their offices in China. However, Ireland has lost ground since Chinese premier Xi Jinping visited Ireland in 2012. Earlier this year, Mr Jinping’s first trip to Europe since 2019, the focus of his visit was Hungary and Serbia, the two largest recipients of Chinese foreign direct investment [FDI] in Europe during the past three years. Losing China's attention Between 2021 and 2023, China-based companies made €11.2bn of investment pledges in Hungary, and €6.5bn in Serbia, more than in any other European country. Compared to the cumulative €9.2bn Chinese investment to date into Ireland, it is clear that we are losing the attention of the Asian mega power. Mr Jinping’s trip is an “indicator of how different the world is today” and reveals a shift in China’s strategy in Europe towards smaller economies which are “willing to stand shoulder to shoulder” with Beijing. Getting closer to China is clearly a prerequisite for ensuring more FDI investments from Chinese companies, but it also puts the Irish Government in the diplomatically awkward position of luring many of the very Chinese companies that the US has sanctioned. Two examples are the telecoms firm Huawei and drugs company WuXi Biologics. In May, Ireland’s minister of state for trade promotion, Dara Calleary, welcomed a report celebrating how Huawei was contributing €800m per year to the Irish economy. The firm has three research and development centres in Ireland. This is the same Huawei whose telecoms equipment the US has banned since 2022 due to concerns over national security Britain has moved in the same direction, ordering phone networks to remove Huawei components, and mobile phone networks in many Western nations, including Ireland, no longer offer Huawei handsets. Meanwhile, WuXi has, since 2018, invested more than €1bn in a facility in Dundalk. Earlier this month, the US House of Representatives passed a bill to restrict US firms’ ability to work with WuXi, again citing national security concerns. In 2020, some 25 Chinese companies had operations in the Republic of Ireland. By this year, the number had jumped to 40 — inclusive of the European headquarters of TikTok, Temu, and Shein — but this is still minuscule to the 970 US corporations here. Given how much Ireland’s economy depends on FDI, some economists say Chinese investment in Ireland can be seen as a welcome insurance policy in case some US firms pull out. Others say Ireland is playing a “dangerous geopolitical game” for a small economy.TOKYO , Dec. 15, 2024 /PRNewswire/ -- Representatives from China and Japan shared their insights on promoting artificial intelligence (AI) governance and data sharing at a sub-forum of the 20th Beijing-Tokyo Forum in Tokyo recently. The sub-forum contributed eastern wisdom to AI governance and digital social development, demonstrating the significance of international cooperation for the development of the digital economy, according to Gao Shaolin, advisor at Peking University's Legal Artificial Intelligence Research Center. AI governance framework The participants agreed that the next 10 years will be a critical period for the development of AI. Gao Wen, academician of the Chinese Academy of Engineering (CAE), said since China's State Council issued a guideline on developing AI in 2017, the nation has made significant progress in AI research and development and industrial layout, especially in computing power and 5G network construction. By the end of 2023, China had over half of the world's 1.57 billion 5G users, according to the World Internet Development Report 2024. It ranked second globally in AI and computing power scale, which has laid a solid foundation for the rapid development of AI. Tatsuo Yamazaki , project professor at the International University of Health and Welfare, said it was very meaningful for Japan and China to discuss strengthening AI governance rules. Fumihiko Kamio , research director of the Nomura Research Institute, echoed his view. He emphasized that the core goal of AI technology is to improve productivity and eliminate obstacles to social development, and called on Chinese and Japanese experts to work together to build an AI governance framework to cope with the global challenges. Deepening international cooperation China put forth the Global AI Governance Initiative in October last year. In July, the UN General Assembly adopted a China -sponsored resolution on enhancing international cooperation on AI capacity-building. The participants spoke highly of the Global Cross-Border Data Flow Cooperation Initiative recently proposed by China . They agreed that AI governance requires global collaboration, especially in the formulation of international standards and the construction of ethical frameworks, where China and Japan can play an active role. Ding Wenhua, academician of the CAE, said China and Japan have both similarities and differences in technology development and governance priorities, so deepening cooperation will bring unique value to global AI governance. " China and Japan should deepen AI technology cooperation between enterprises, work together in AI security research, talent exchange, and jointly explore more possibilities for the application of technology," Wang Zhongyuan , president of the Beijing Academy of Artificial Intelligence, said. Balancing development & risks AI governance refers to the guardrails established to ensure AI systems and tools remain safe and ethical and respect human rights. Xu Zhilong , editor-in-chief of Science and Technology Daily, stressed that AI, as a revolutionary technology, has far-reaching impacts on all areas of society and economy. However, its potential risks such as data leakage and the spread of false information should not be ignored. "Technological progress and security ethics should be developed in a balanced way to ensure that AI technology always serves the progress of human civilization," Xu said. AI governance should not only heed the current technological ethics issues, but also prevent possible long-term risks, such as AI going out of human control, according to Toshio Iwamoto , senior corporate advisor of NTT DATA. He said AI R&D and application should abide by the principles of fairness, transparency, safety and availability. Yuan Yue, chairman of Beijing Dataway Horizon, shared his view from the perspective of regulatory models. "Policy choices should be based on the current status and goals of national technological development," Yuan said, adding that China prefers to provide a more friendly development environment for enterprises while ensuring an effective response to risks. View original content to download multimedia: https://www.prnewswire.com/news-releases/science-and-technology-daily-promoting-ai-governance-jointly-302332050.html SOURCE Science and Technology Daily

Finding the perfect gift can be daunting. The only way to truly ensure you get it right would be to ask the recipient what they want, but that wouldn’t be much fun for either of you. Luckily, there’s another tactic to help you earn a “gift whisperer” reputation: seeking out unique, practical, game-changing gifts that will truly surprise and delight. But that’s about as easy as it sounds, which is to say it’s not easy at all. So, we’ve done the legwork for you. Start making your list with this compilation of some of the most innovative, functional and fun gifts of 2024. There’s something for every budget. Bear with me: The new FinaMill Ultimate Spice Grinder set elevates the pedestrian pepper and spice mill in both function and style. Available in three colors (Sangria Red, Midnight Black and Soft Cream), the rechargeable-battery unit grinds with a light touch rather than hand-tiring twists. That’s easier for everyone and especially helpful for those experiencing hand or wrist issues such as arthritis, carpal tunnel syndrome or tendinitis. And it’s fun to use. The set includes a stackable storage tray and four pods that can be easily swapped as needed: The GT microplane grater for hard spices, nuts and chocolate; the MAX for large spices and dried herbs; the ProPlus for smaller and oily spices; and the Pepper Pod for, well, pepper. $110. Campers and backyard firepit lovers who have experienced the heartbreak of wet wood will appreciate having a three-pack of Pull Start Fire on hand. Made of 89% recycled materials, including sanding dust, wax and flint, the food-safe, eco-friendly, 3-by-2-by-1-inch fire starters will light a fire quickly without matches, lighters or kindling. Just loop the attached green string around a log, incorporate it into a wood stack, and pull the attached red string to ignite. Each windproof, rainproof block burns for 30 minutes. $29.99. The No Mess Utensil Set from Souper Cubes, a company known for its portioned, silicone freezer trays, lives up to its name. The utensils — a serving spoon and a ladle — have innovative, S-shaped handles designed to rest on the edge of a pot, keeping them upright so they won’t slip in. The design also eliminates the need for a spoon rest or, worse, placing dirty utensils on the kitchen counter or stovetop between stirs. A silicone coating in a choice of Aqua, Charcoal, Cranberry or Blueberry keeps handles cool to the touch. $24.99. The FeatherSnap Wi-Fi smart bird feeder could turn anyone into an avid birdwatcher. Equipped with an HD camera, the dual-chamber feeder enables up-close livestreaming of avian visitors, as well as species-logging via the free mobile app. An optional premium subscription ($59.99 annually or $6.99 monthly) includes unlimited photo and video storage, AI identification with species-specific details, and the opportunity to earn badges for logging new visitors. Turn on notifications to get alerts sent to your phone whenever there’s activity at the feeder. $179.99. Fujifilm's Instax Mini Link 3 smartphone printer offers a touch of nostalgia without sacrificing technology. Just load the 4.9-by-3.5-by-1.3-inch printer with Instax Mini instant film and connect it to your Android or iOS device via Bluetooth to print wallet-size photos. If you want to get fancy, you can adjust brightness, contrast and saturation, or apply filters, including 3D augmented-reality effects, via the free Instax Mini Link app. It can also make collages of up to six images, or animate photos to share on social media. Available in Rose Pink, Clay White and Sage Green. $99.95. The appropriately named easyplant is one of the best gifts you can give your houseplant-loving friends, regardless of their experience level. Select a pot color, size and plant (or get recommendations based on sunlight requirements, pet friendliness and other attributes) and fill the self-watering container’s built-in reservoir roughly once a month. Moisture will permeate the soil from the bottom as needed, eliminating the often-fatal consequences of over- or under-watering. It’s also a literal lifesaver come vacation time. $49-$259. If you’ve got a no-dairy friend on your list, a plant-based milk maker could save them money while allowing them to avoid sugar, stabilizers, thickeners and preservatives. The Nama M1 appliance both blends and strains ingredients, converting nuts, seeds, grains or oats into velvety-smooth milk in just one minute, with zero grit. And for zero waste, the pasty leftover pulp can be used in other recipes for added nutrients. The device also makes infused oils, flavored waters and soups. And, importantly, cleanup is easy. Available in white and black. $400. For friends who prefer stronger beverages, the QelviQ personal sommelier uses “smart” technology to ensure wine is served at its ideal temperature. Unlike traditional wine refrigerators, this device doesn’t take up any floor space. It also doesn’t chill wine to just one or two temperatures based on its color. Instead — paired with the free QelviQ app — the tabletop chiller relies on a database of more than 350,000 wines to bring a bottle to its specific recommended serving temperature in as little as 20 minutes. It also suggests food-wine and wine-food pairings. Plus, the appliance serves as a great icebreaker to inspire dinnertime conversation. Available in Exciting Red, Dashing Black and Dreamy White. $495. Grilling food after dark — and ascertaining its doneness — can prove challenging without outdoor lighting, and it’s nearly impossible to cook while holding a flashlight. But as is often the case, the simplest of solutions can make the biggest of impacts: Uncommon Good’s 2-piece LED Grilling Tool Set puts illumination into the handles of its stainless-steel spatula and tongs. After use, the lights can be removed and the utensils run through the dishwasher. $40.

Ex-Google CEO Eric Schmidt says human operators need to have ‘meaningful control’ of AI drones in warfare

ASML Deadline: ASML Investors with Losses in Excess of $100K Have Opportunity to Lead ASML Holding N.V. Securities Fraud Lawsuit

Arlocabtagene autoleucel is a gene-modified cell therapy commercialized by , with a leading Phase II program in Relapsed Multiple Myeloma;Refractory Multiple Myeloma. According to Globaldata, it is involved in 5 clinical trials, of which 4 are ongoing, and 1 is planned. Smarter leaders trust GlobalData The gold standard of business intelligence. The revenue for Arlocabtagene autoleucel is expected to reach an annual total of $18 mn by 2039 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress. Arlocabtagene autoleucel Overview Bristol-Myers Squibb Overview (BMS) is a specialty biopharmaceutical company. It is engaged in the discovery, development, licensing and manufacturing, marketing, distribution and sale of medicines and related medical products to patients with serious diseases. Its primary focus is on cancer, immunology, cardiovascular, and fibrotic diseases. The company offers its products across the world to wholesalers, retail pharmacies, medical professionals, hospitals and government entities. The company has an operational presence in the US, Switzerland, Puerto Rico, Ireland, and the Netherlands. The company conducts research to focus on the discovery and development of novel medicines that address diseases in areas of unmet medical need. BMS is headquartered in Princeton, New Jersey, the US. The company reported revenues of (US Dollars) US$45,006 million for the fiscal year ended December 2023 (FY2023), a decrease of 2.5% over FY2022. In FY2023, the company’s operating margin was 20.9%, compared to an operating margin of 20.9% in FY2022. In FY2023, the company recorded a net margin of 17.8%, compared to a net margin of 13.7% in FY2022. The company reported revenues of US$12,201 million for the second quarter ended June 2024, an increase of 2.8% over the previous quarter. For a complete picture of Arlocabtagene autoleucel’s valuation, From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company. The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s .

Our community members are treated to special offers, promotions and adverts from us and our partners. You can check out at any time. More info Motherwell and Wishaw MSP Clare Adamson has urged unpaid carers to check their eligibility for financial support from Social Security Scotland. The call comes following the figures in the latest census, which show that there are 45,300 unpaid carers in North Lanarkshire. Ms Adamson also warned that many people who care for a friend or loved one do not think of themselves as a carer. The MSP added that it was important to register with a local carers’ organisation for advice and support. Earlier in November, Scotland’s Carer Support Payment, which replaces Carer’s Allowance in Scotland, was rolled out across the country, expanding eligibility to those who are in full-time education, and introducing backdating for some applicants. The Lanarkshire Live app is available to download now. Get all the news from your area – as well as features, entertainment, sport and the latest on Lanarkshire’s recovery from the coronavirus pandemic – straight to your fingertips, 24/7. The free download features the latest breaking news and exclusive stories, and allows you to customise your page to the sections that matter most to you. Head to the App Store and never miss a beat in Lanarkshire - iOS - Android This joins a suite of support for carers only available in Scotland, like the Young Carer Grant and Carer’s Allowance Supplement. Ms Adamson said: “The nationwide rollout of the Carer Support Payment is a big moment for Scotland. “There are 45,300 unpaid carers across North Lanarkshire and that figure is likely an underestimate. “Unpaid carers are performing critical roles in our community; it is a difficult and demanding role. I want to ensure that no one is missing out on financial support that they are entitled to. “The SNP developed Social Security Scotland with the principles of dignity, fairness and respect in its founding principles. The new Carer Support Payment improves on Carer’s Allowance by making those in full time education eligible and introducing backdating for some applicants. “So if you are caring for someone – a neighbour, friend, or loved one – please check your eligibility for extra support through Social Security Scotland. And ensure you are registered with a carers’ organisation.” You can apply for Carer Support Payment using the online form, on the phone, by post, or in person. Find out more about Carer Support Payment online at mygov.scot/carer-support-payment or call Social Security Scotland free on 0800 182 2222. *Don't miss the latest headlines from around Lanarkshire. Sign up to our newsletters here . And did you know Lanarkshire Live had its own app? Download yours for free here .WARMINGTON: They call it ‘winter village,’ but it will always be Toronto’s Christmas market