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“My twin sister Nicola got sick when she was 24 years old. It was determined that she had stomach cancer and passed away two months to the day she was diagnosed.” Natasha Benn lost her sister to a rare and aggressive form of stomach cancer in 1993. Before Nicola, her mother had passed away from the same cancer when Benn was two. So did her grandmother, aunt, and great-grandfather. “My dad always thought it might be some kind of hereditary component to the type of cancer that my mom had, but it was never confirmed at the time,” Benn said. Shortly after Nicola's death, a gastroenterologist strongly suggested that Benn undergo surgery to remove her stomach, given the close genetic link between the twins. Nine months later, the young woman decided to go forward with full gastrostomy, unbeknownst to her if she was carrying the same ailment. Grieving the loss of her sister and uncertain if she had made the right decision, Benn received news six years later confirming her choice had been the correct one. After performing a biopsy on the young woman’s stomach, pathologists discovered traces of cancer in the organ’s lining - something that could not have been detected even with an endoscopy. Little did they know, the Benns, along with another family from Detroit, were part of a groundbreaking discovery that transformed the lives of countless families. For the first time in history, researchers identified a genetic mutation in Natasha’s stomach which they named CDH1. This mutation was found to carry an 83 per cent risk of developing stomach cancer and 60 per cent likelihood of lobular breast cancer. Thanks to the technological advances and research, organizations like BC Cancer can find this mutation through risk-free, non-evasive, and efficient ways. A simple sample of saliva, or blood, can be all that’s needed to determine if one carries the rogue gene. “Genetic testing can be helpful in clarifying whether or not you have an increased risk [of cancer] and then determining what's available in terms of screening and prevention for those specific types of cancer,” said Jennifer Nuk, leader in genetic counsellor for the BC Cancer Hereditary Cancer Program. For decades, identifying hereditary cancer solely relied on analyzing one’s family history, without having certainty if members were carriers of the ailment, explained Nuk. In the early days of genetic testing, means were limited, costly, and slow. Today, however, researchers can examine more genes than ever before with greater efficiency, at a higher rate, for a fraction of what it once cost. “We've had families that were seen years ago where it looks like there was something going on in the family... and we didn't find anything,” said Nuk. “Now we go back to test that same family [and] we're actually picking up mutations because the technology has improved so much.” Though many remain to be studied, Nuk and her team can now detect rogue genes causing numerous cancers including ovarian, breast, and colon. The lead geneticist added that the services offered by the program are twofold; genetic testing to identify individuals carrying mutated genes, and the provision of personalized care plans for those at increased cancer risk. “If we can figure out someone's at higher risk... we have a much better chance of offering better outcomes for the patient,” she said. People are provided with comprehensive information and a range of options, allowing them to make informed decisions about their next steps. As prevention is key to combating cancer, Nuk and her team will discuss and propose to their patients appropriate screening options, such as mammograms or MRIs, as well as preventative measures like vaccines and surgeries suited to their respective conditions. In turn, Nuk added that if one treatment can be given over another more invasive one, this will ultimately result in a better quality of life for individuals and benefit the overall health-care system. Since its inception in 1997, the prevention program has not only saved thousands of lives but also reduced health-care costs for taxpayers, freed up time and resources for other cancer patients, and alleviated the burden on B.C.'s hospitals. Benn and her sisters benefited from this very program. “My older sister did have the gene and decided to go through with the surgery and had her stomach removed,” she said. “[It] was riddled with cancer and she's still living today.” Her other sister, luckily, tested negative for the CDH1 mutation. Benn herself, facing a significant breast cancer risk from possessing the gene, opted for a preventative mastectomy. Reflecting on her journey, the self-proclaimed “cancer avoider” acknowledges the challenges she faced, including the grief of losing her sister and the uncertainty that followed her surgery. However, she strongly recommends the importance of prioritizing preventative care. “To have that knowledge and to be willing to [use it] is so important,” said Benn. “I know a lot of people avoid going to the doctor, especially when you might be feeling completely healthy, but you don't know what else is happening in your body. “Having a screening place that you can go to determine if you have a history of any kind of illness that you can prevent it in advance, why wouldn't you go?”

( MENAFN - GetNews) Heritage of Excellence, Advancing with Honor. On November 25, the highly anticipated 15th Annual Construction Machinery Brand Ceremony was grandly held in Shanghai. During the event, the 2024 Top 10 Rankings of the Construction Machinery Industry were officially released. This prestigious conference honored the influential brands and outstanding products that emerged over the past year. By setting exemplary benchmarks for the industry, the event aims to promote industrial prosperity, foster innovation, and drive transformative development across the sector. Amid the overlapping trends of a new global energy revolution and deep technological innovation, the construction machinery industry is accelerating its transformation toward high-end, intelligent, and green development. Product lines for primary machinery have become increasingly diverse, with continuous improvements in quality and performance. Guided by industrial policies aimed at supplementing, strengthening, and extending supply chains, significant progress has been made in key core component technologies, providing robust support for collaborative development between primary and supporting enterprises, as well as for the industry's quality improvement and upgrading. At the same time, the vast stock market of existing equipment, combined with the push for large-scale equipment upgrades, has spurred new focus and positioning in aftermarket operations, including equipment leasing, spare parts distribution, maintenance services, and the trading of second-hand equipment. This selection process adhered to principles of rigor, authority, fairness, and objectivity. After three stringent rounds of evaluation-online voting, user scoring, and expert review-a new cohort of outstanding enterprises and products in the fields of machinery, components, and industry user applications emerged. These exemplary winners set a benchmark for the continued growth and innovation of the construction machinery industry. Click the link to view the complete list of award-winning companies. Adhering to the principle of "Building Brands, Strengthening Technology, and Shaping the Power and Value of Enterprises," the Brand Ceremony has been held for 15 consecutive years. It has consistently exerted remarkable influence within the industry, serving as a driving force for its development and earning widespread acclaim and support from industry professionals. Each edition of the Brand Ceremony aligns closely with the pulse of the times, celebrating the spirit of exceptional brands while inspiring numerous enterprises to pursue paths of branding and high-end development. The release of the industry rankings highlights the industry's recognition of companies' core technological capabilities and innovative product strength. This not only empowers enterprises with the "wings to soar" in their brand development but also injects fresh vitality into the sustainable growth of China's construction machinery industry! MENAFN23122024003238003268ID1109025386 Legal Disclaimer: MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above.Orla/iStock via Getty Images Introduction Opendoor ( NASDAQ: OPEN ) — the number one e-commerce platform for residential real estate — is by far the worst-performing stock in my portfolio, down more than 50% YTD. I must admit, it has been incredibly frustrating holding the stock despite the Analyst’s Disclosure: I/we have a beneficial long position in the shares of OPEN either through stock ownership, options, or other derivatives. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article. Seeking Alpha's Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.DETROIT – China will soon see a massive expansion of electric vehicle battery swapping, as global battery maker CATL said Wednesday it is investing heavily in stations there next year. Battery swapping is not new — but it's had a challenging journey. Adoption of electric vehicles has varied in regions across the globe over the past several years, and that doesn't always bode well for building new infrastructure. Recommended Videos While the technology could do well in China, it's uncertain whether it could work in other countries. What is battery swapping? Battery swapping allows EV drivers to pull into a station on a low battery and receive a swapped, fully-charged battery within minutes. An EV has to be equipped with the right technology to receive a swap — and not many models around the world currently have it. Automakers have to buy into the idea, and EV adoption among consumers also has to grow, so that investing in new infrastructure seems worthwhile. Consumers also have to be comfortable not owning their battery. Why could it work in China? China is much further along in adopting EVs than other countries. Not only is it the world's largest auto market, but in July, the country hit a milestone with 50% of new sales electric — and it accounts for most of this year's global EV sales. China supports EV growth through government subsidies and mandates. So it makes more sense for companies to invest in unique EV infrastructure there because that's more likely to be needed. What other attempts at battery swapping have occurred? The most notable example might be Israeli startup Better Place, which tried its hand at swapping in 2007. But the company shut down a few years later after investing a lot of money and coming up against roadblocks with logistics. EV adoption was especially low at the time. Could it work in the United States? Europe? Startup Ample, for example, has a modular battery swapping station that it says can complete a swap in 5 minutes. That’s important as charging time remains a point of concern for prospective EV buyers. Even the fastest fast chargers could take at least 15 minutes for a decent charge. But in the U.S., pure EVs only accounted for 8% of new vehicle sales as of November. Meanwhile Nio, a rival Chinese EV brand, has about 60 swap stations in northern Europe, and the EV adoption is higher there than the U.S., but the same challenges remain. Different automakers put different batteries in their various EV models, so a station would need all of those available if the industry didn't agree to a standardized battery, and not all of those models are out yet in volume. This is something that really needs scale. Swapping could help with EV cost — currently a barrier to adoption for many — because a driver wouldn’t necessarily own the most expensive part of an EV: the battery. Greg Less, director of the University of Michigan Battery Lab, said with proper framing and education, people might like the idea of battery swapping. To him, it's not unlike buying a propane-fueled grill and purchasing a refilled tank every so often. But it would require a rethinking of car ownership. "Where I could see it working is if we went entirely away from vehicle ownership and we went to a use-on-demand model," Less added. “I don’t think we’re there yet.” What vehicle uses might be b est for swapping? Battery swapping might make most sense for ride-sharing or other fleet vehicles. Drivers of buses, taxis, Uber or Lyft vehicles want to spend as much time on the road as possible, transporting customers and making money. If battery swapping can shorten the time needed to charge EVs, that makes driving one less disruptive to their business. ___ Alexa St. John is an Associated Press climate solutions reporter. Follow her on X: @alexa_stjohn . Reach her at ast.john@ap.org . ___ Read more of AP’s climate coverage at http://www.apnews.com/climate-and-environment ___ The Associated Press’ climate and environmental coverage receives financial support from multiple private foundations. AP is solely responsible for all content. Find AP’s standards for working with philanthropies, a list of supporters and funded coverage areas at AP.org .

What a merger between Nissan and Honda could mean for automakers and the industry

Two people have been taken to hospital after a gas explosion at a terraced house in east London. Footage on social media showed the moment of the blast on a residential street in Ilford - which caused a fire that significantly damaged the roof, both of its floors and the loft conversion. The house had been converted into flats, the London Fire Brigade said. Some 60 firefighters were sent to tackle the blaze on Ley Street and two people were rescued from a first-floor window using a ladder. They were taken to hospital by the London Ambulance Service. Two neighbouring properties are being assessed by a dangerous structures engineer, the London Fire Brigade said. Emergency services took the first calls about the fire at 4.09pm and it was brought under control by 6.23pm. Crews will remain on the scene throughout the evening. Station commander Darren McTernan said: "Ley Street remains closed between Eastern Avenue and Vicarage Road, impacting traffic in the surrounding area, so please continue to avoid the area if you can." A London Ambulance Service spokesman said: "We sent resources including ambulance crews, an advanced paramedic practitioner, an incident response officer and members of our hazardous area response team. "We treated three people. We took two to hospital and discharged a third at the scene," they added. The London Fire Brigade said the cause of the explosion was being investigated.

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General Motors said Tuesday it will retreat from the robotaxi business and stop funding its money-losing Cruise autonomous vehicle unit. Instead the Detroit automaker will focus on development of partially automated driver-assist systems for personal vehicles like its Super Cruise, which allows drivers to take their hands off the steering wheel. > Watch NBC Bay Area News 📺 Streaming free 24/7 GM said it would get out of robotaxis “given the considerable time and resources that would be needed to scale the business, along with an increasingly competitive robotaxi market.” The company said it will combine Cruise's technical team with its own to work on advanced systems to assist drivers. GM bought control of San Francisco-based Cruise automation in 2016 with high hopes of developing a profitable fleet of robotaxis. Over the years GM invested billions in the subsidiary and eventually bought 90% of the company from investors, all while racking up millions in losses. GM’s brushoff of Cruise represents a dramatic about-face from years of full-blown support that left a huge financial dent in the automaker. The company invested $2.4 billion in Cruise only to sustain years of uninterrupted losses, with little in return. Since GM bought a controlling stake in Cruise for $581 million in 2016, the robotaxi service piled up more than $10 billion in operating losses while bringing in less than $500 million in revenue, according to GM shareholder reports filed with the Securities and Exchange Commission. The automaker even announced plans for Cruise to generate $1 billion in annual revenue by 2025, but it scaled back spending on the company after one of its autonomous Chevrolet Bolts dragged a San Francisco pedestrian who was hit by another vehicle in 2023. The California Public Utilities Commission alleged Cruise then covered up details of the crash for more than two weeks. The embarrassing incident resulted in Cruise’s license to operate its driverless fleet in California being suspended by regulators and triggered a purge of its leadership — in addition to layoffs that jettisoned about a quarter of its workforce. GM CEO Mary Barra told analysts on a conference call Tuesday the the new unit will focus on personal vehicles and developing systems that can drive by themselves in certain circumstances. The company has agreements to buy another 7% of Cruise and intends to buy the remaining shares so it owns the whole company. The move is another step back from autonomous vehicles, which have proved far harder to develop than companies once anticipated. Two years ago, crosstown rival Ford Motor Co. disbanded its Argo AI autonomous vehicle venture in Pittsburgh that it co-owned with Volkswagen. At the time the company said it didn’t see a path to profitability for a number of years. Yet other companies are pressing forward with plans to deploy autonomous vehicles and expanding their services. Alphabet Inc.'s Waymo is accelerating plans to broaden its robotaxi service beyond areas of metropolitan Phoenix, San Francisco and Los Angeles. Last week the company said it would begin testing its driverless Jaguars in Miami next year, with plans to start charging for rides in 2026. The move comes less than a month after Waymo opened up its robotaxi service to anyone looking for a ride in an 80-square-mile (129 square kilometer) area of Los Angeles. Waymo also has plans to launch fleets in Atlanta and Austin next year in partership with ride-hailing leader Uber. In April, a company called Aurora Innovation plans to start hauling freight on Texas freeways using fully driverless semis. Tesla CEO Elon Musk has said his company plans to have autonomous Models Y and 3 running without human drivers next year. Robotaxis without steering wheels using Tesla's “Full Self-Driving” system would be available in 2026 starting in California and Texas, he said. But an investigation by the National Highway Traffic Safety Administration into Full Self-Driving's ability to see in low visibility conditions cast doubt on whether Teslas are ready to be deployed without humans behind the wheel. The agency began the investigation in October after getting reports of four crashes involving “Full Self-Driving” when Teslas encountered sun glare, fog and airborne dust. An Arizona pedestrian was killed in one of the crashes. GM said it will work with Cruise’s leadership to restructure the company and refocus Cruise’s operations on driver assist systems. The company expects the restructuring to reduce spending by more than $1 billion annually. Cruise has about 2,300 employees and will retain a presence in San Francisco, GM said. It’s too early to talk about employment levels until the restructuring is completed next year, a spokesman said. Dave Richardson, senior vice president of software and services engineering, said Cruise will bring its software, artificial intelligence and sensor development to GM to team up on improving GM’s driver-assist systems. “We want to leverage what already has been done as we go forward, and we think we can do that very effectively,” Barra said. Shares of GM rose about 3% in trading after Tuesday's closing bell. They are up about 47% for the year. _____ AP Technology Writer Michael Liedtke in San Francisco contributed to this report.

N.S. Tories seek 'fresh' mandate in Tuesday's election to negotiate with OttawaHAMILTON, Ontario, Nov. 25, 2024 (GLOBE NEWSWIRE) -- Manufacturing is essential to the Canadian economy, contributing approximately 10% of our GDP. Two of the biggest challenges facing manufacturers is ensuring that their workers have the right skills to support them as they take on new technologies and practices, and onboarding enough new workers to support sustained operations and growth. These challenges will be exacerbated as more of the existing workforce enters retirement. Introducing automation and other digital technologies has been proposed as a solution to address the skills gap, but it poses its own set of unique challenges. Canada’s Occupational and Skills Information System (OaSIS) contains data on the competencies required to work in 900 different occupations, providing the users with a standardized way to understand how competencies vary by level of proficiency across occupations. With the rapid adoption of technologies, can the OaSIS database support the future needs of the manufacturing sector? Also, is there alignment of skills and competencies across manufacturing subsectors? In one study conducted under NGen’s Future Ready program, funded in part by ESDC’s Sectoral Workforce Solutions Program (SWSP), the cluster contracted 6 industry associations (APMA, BioTalent Canada, CMISA, DAIR, FPSC, and SIMSA) to engage their members to help generate a snapshot of the current skills and proficiencies of the Canadian manufacturing workforce, and how those skills and proficiencies are projected to evolve through 2040. In total, 157 Canadian manufacturers participated in this study. Projected skill levels for 2030 and 2040 indicate an emerging emphasis on digital literacy, cognitive skills, and soft skills, with the largest changes in projected proficiencies occurring in Digital Literacy, Problem Solving, and Creativity and Innovation. The results paint a picture of a digitally literate workforce that will require cognitive and soft skill enhancement to be effective in the digital work environment of the future. These findings suggest that manufacturing needs to understand and prepare for changes in competencies across all job functions. This will require a strategy of incorporating continuous upskilling and recruitment within and across the manufacturing sector. Another important finding was that there is a great deal of commonality across the various sectors of manufacturing and across regions, meaning that pan-Canadian, cross-sectoral solutions have the potential to drive tremendous economic impact. To read more about NGen’s workforce research initiatives, visit www.ngen.ca/futureready . Research Papers Decarbonization and its Impact on Canada's Manufacturing Workforce Digitizing Canada's Advanced Manufacturing Sector: Reshaping Jobs and Skills Technological Innovation and Workforce Diversity in the Advanced Manufacturing Sector The Manufacturing Workforce: Trends and Opportunities An Assessment of the Changing Skill Needs of the Canadian Manufacturing Workforce Artificial Intelligence in Manufacturing: The Evolution of Technology and Jobs in the Sector Digitizing Canada's Manufacturing Sector Equity, Diversity and Inclusion Toolkit Advanced Manufacturing Skills Catalogue Best Practices for Newcomers Labour Market Intervention Programmes Quotes “We believe that our manufacturing workforce is a critical national asset and must be looked at through a pan-Canadian, cross-sectoral lens. Through our collaboration with six organizations supporting specific manufacturing sectors, we have identified common core competencies as well as common skills challenges facing Canada’s manufacturing sector which provides nearly ten percent of Canada’s GDP.” - Stewart Cramer, Chief Manufacturing Officer, NGen “As the lead skills training organization for Canada's food and beverage manufacturing industry, we know — as do businesses — that upskilling and continuous learning is fundamental to any successful workforce. Skills training values individuals and supports recruitment and retention." - Jennefer Griffith, Executive Director, Food Professing SKills Canada "Transitions aren’t only about innovation and technology. The companies that get it right are the ones that will bet on their current workforce with new skills, patience and direction. The jurisdictions that will lead in the new automotive will be the ones that partner with those companies and workers to chart their path." - Flavio Volpe, President, APMA “The Saskatchewan labour market is very competitive, and the manufacturing market has a difficult time competing with other booming, high productivity markets such as mining, energy and tech. The skill trend analysis we did in partnership with NGen underscores a dynamic shift in occupational competencies, highlighting the move from solely technical skills to a more broadly skilled and adaptable workforce across various sectors. Research of this kind is essential to our ability to build the workforce that we will need to compete and grow not only against our global competitors, but also in the fierce competition for talent in our home province of Saskatchewan. SIMSA greatly appreciates the support of and invaluable work by NGen!” - Eric Anderson, Executive Director, SIMSA About NGen NGen is the industry-led not-for-profit organization that leads Canada’s Global Innovation Cluster for Advanced Manufacturing. Its mandate is to help build world-leading advanced manufacturing capabilities in Canada for the benefit of Canadians. NGen works to strengthen collaboration among its membership of more than 5,000 manufacturers, technology companies, innovation centres, and researchers, and provides funding and business support to industry-led initiatives that aim to develop, apply, or scale-up transformative manufacturing solutions in Canada for commercialization in global markets. www.ngen.ca/membership . Media Contact Robbie MacLeod Robbie.macleod@ngen.ca 613-297-3578

China's getting a big electric car battery swapping boost in 2025. Would that work across the globe?MUMBAI: The Adani group’s defence arm, Adani Defence Systems & Technologies Ltd (ADSTL), has signed an agreement to acquire an 85.8% stake in Air Works, India’s largest private-sector Maintenance, Repair and Overhaul (MRO) company. With operations across 35 cities and a workforce of over 1,300 personnel, Air Works brings extensive expertise in servicing both fixed-wing and rotary-wing aircraft. The acquisition enhances Adani’s capabilities in the defence MRO sector, solidifying its position in India’s airborne defence ecosystem. Air Works, founded in Mumbai in April 1951 but now headquartered in Delhi, offers aviation services such as spanning line maintenance, heavy checks, interior refurbishment, painting, redelivery checks, avionics as well as aircraft management services for Indian and global customers. The company undertakes base maintenance for narrow-body and turboprop aircraft, as well as rotary aircraft from its facilities in Hosur in Karnataka, Mumbai and Kochi. In addition to civil aviation, Air Works has significant capabilities in defence MRO, executing projects for the Indian Navy and Indian Air Force. Jeet Adani, director of Adani Airports said, “The Indian aviation industry stands at a transformative juncture, now the third-largest globally and on track to induct over 1,500 aircraft in the coming years.”Some elite U.S. universities — including Penn — favor wealthy students in admissions decisions, lawsuit alleges

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