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As part of a national “moonshot” to cure blindness, researchers at the CU Anschutz Medical Campus will receive as much as $46 million in federal funding over the next five years to pursue a first-of-its-kind full eye transplantation. “This is no easy undertaking, but I believe we can achieve this together,” said Dr. Kia Washington, the lead researcher for the University of Colorado-led team, during a press conference Monday. “And in fact I’ve never been more hopeful that a cure for blindness is within reach.” The CU team was one of four in the United States that received funding awards from the federal Advanced Research Projects Agency for Health , or ARPA-H. The CU-based group will focus on achieving the first-ever vision-restoring eye transplant by using “novel stem cell and bioelectronic technologies,” according to a news release announcing the funding. The work will be interdisciplinary, Washington and others said, and will link together researchers at institutions across the country. The four teams that received the funding will work alongside each other on distinct approaches, though officials said the teams would likely collaborate and eventually may merge depending on which research avenues show the most promise toward achieving the ultimate goal of transplanting an eye and curing blindness. Dr. Calvin Roberts, who will oversee the broader project for ARPA-H, said the agency wanted to take multiple “shots on goal” to ensure progress. “In the broader picture, achieving this would be probably the most monumental task in medicine within the last several decades,” said Dr. Daniel Pelaez of the University of Miami’s Bascom Palmer Eye Institute, which also received ARPA-H funding. Pelaez is the lead investigator for that team, which has pursued new procedures to successfully remove and preserve eyes from donors, amid other research. He told The Denver Post that only four organ systems have not been successfully transplanted: the inner ear, the brain, the spinal cord and the eye. All four are part of the central nervous system, which does not repair itself when damaged. If researchers can successfully transplant the human eye and restore vision to the patient, it might help unlock deeper discoveries about repairing damage to the brain and spine, Pelaez said, as well as addressing hearing loss. To succeed, researchers must successfully remove and preserve eyes from donors and then successfully connect and repair the optical nerve, which takes information from the eye and tells the brain what the eye sees. A team at New York University performed a full eye transplant on a human patient in November 2023, though the procedure — while a “remarkable achievement,” Pelaez said — did not restore the patient’s vision. It was also part of a partial face transplant; other approaches pursued via the ARPA-H funding will involve eye-specific transplants. Washington, the lead CU researcher, said she and her colleagues have already completed the eye transplant procedure — albeit without vision restoration — in rats. The CU team will next work on large animals to advance “optic nerve regenerative strategies,” the school said, as well as to study immunosuppression, which is critical to ensuring that patients’ immune systems don’t reject a donated organ. The goal is to eventually advance to human trials. Pelaez and his colleagues have completed their eye-removal procedure in cadavers, he said, and they’ve also studied regeneration in several animals that are capable of regenerating parts of their eyes, like salamanders or zebra fish. His team’s funding will focus in part on a life-support machine for the eye to keep it healthy and viable during the removal process. InGel Therapeutics, a Massachusetts-based Harvard spinoff and the lead of a third team, will pursue research on 3-D printed technology and “micro-tunneled scaffolds” that carry certain types of stem cells as part of a focus on optical nerve regeneration and repair, ARPA-H said. ARPH-A, created two years ago, will oversee the teams’ work. Researchers at 52 institutions nationwide will also contribute to the teams. The CU-led group will include researchers from the University of Southern California, the University of Wisconsin, Indiana University and Johns Hopkins University, as well as from the National Eye Institute . The teams will simultaneously compete and collaborate: Pelaez said his team has communicated with researchers at CU and at Stanford, another award recipient, about their eye-removal research. The total funding available for the teams is $125 million, ARPA-H officials said Monday, and it will be distributed in phases, in part dependent on teams’ success. U.S. Rep. Diana DeGette, a Democrat who represents Denver in Congress, acknowledged the recent election results at the press conference Monday and pledged to continue fighting to preserve ARPA-H’s funding under President-elect Donald Trump’s administration. The effort to cure blindness, Washington joked, was “biblical” in its enormity — a reference to the Bible story in which Jesus cures a blind man. She and others also likened it to a moonshot, meaning the effort to successfully put Neil Armstrong and Buzz Aldrin on the moon nearly 50 years ago. If curing blindness is similar to landing on the moon, then the space shuttle has already left the launchpad, Washington said. “We have launched,” she said, “and we are on our trajectory.”

70 Gifts under $25 on Amazon that are legitimately amazingAs Premier Doug Ford vows to alleviate Toronto’s infamous traffic congestion, his government’s designs for Ontario Place would add to the problem. That’s the conclusion of a new report from the city of Toronto that examined the projected traffic impacts of the Ontario PC plan to redevelop the lakeside waterpark . The report from city transportation staff noted that the $2.2-billion revamp — consisting of the Therme spa, expanded Live Nation concert venue, new public spaces and a mainland pavilion for Ontario Science Centre programming — will convert the Ontario Place site into a year-round destination. By 2032, the redevelopment is projected to increase traffic volumes on Lake Shore Boulevard West by up to 27 per cent in the morning rush, 23 per cent in the evening rush and as much as 40 per cent during major events like Toronto FC games and the Canadian National Exhibition, according to the report. That would add about 1 to 2 minutes to vehicle travel times on Lake Shore between British Columbia Road and Strachan Avenue during typical weekday or weekend peak periods, the city estimated. During major events, trips would take about 5 to 6.5 minutes longer. The projections, which were based on a previous analysis performed for Infrastructure Ontario by LEA Consulting Ltd., take into account other factors that could affect traffic, such as development applications, corridor growth, new pedestrian promenades, and planned transit improvements in the Ontario Line, Lake Shore West GO upgrades and SmartTrack stations. Ford’s government has signalled that reducing gridlock in Ontario’s biggest city is among its top priorities. In July it announced $73 million to speed up lane-reducing construction on the Gardiner Expressway one year early, and last month it took the extraordinary step of passing legislation that will allow it to remove bike lanes it claims are causing congestion on major Toronto thoroughfares. Asked whether the province was concerned the Ontario Place redevelopment could undermine those traffic-fighting efforts, Ash Milton, press secretary for Infrastructure Minister Kinga Surma, said in an email that the government “is ensuring that Ontario Place and the surrounding area will be served by numerous transport options, including the Ontario Line, which is part of the largest subway expansion in Canadian history.” “We will keep ensuring that residents and businesses in Toronto have the transport options they need as the population continues to grow,” Milton said. But Norm Di Pasquale, co-chair of Ontario Place for All , an advocacy group that opposes the province’s plan, said the report shows the Ontario Place plan would cause “an intense amount of traffic in downtown.” The premier “is manifesting the exact thing that he is saying he is trying to avoid,” argued Di Pasquale. He said that the Ford government’s intention to build 2,500 parking spaces near the Therme spa and relocate the Ontario Science Centre from Flemingdon Park would be major drivers of the worsening congestion. Di Pasquale, whose group has previously criticized the redevelopment over its cost to taxpayers and impact on public space, said the traffic data is further evidence that “this is ultimately the wrong site for both the mega spa and the Ontario Science Centre.” City staff produced the traffic analysis in response to a motion from Deputy Mayor Ausma Malik (Ward 10, Spadina—Fort York) at June’s council meeting. It’s clear the transportation impacts of the province’s proposal “had not been properly considered,” Malik said in a statement Monday, and the new report shows “it will have significant impacts on an already busy corridor,” as well as on congested areas like Liberty Village. She said the Therme development does “not belong on our waterfront.” The report will be debated at Toronto and East York Community Council on Jan. 14, and is scheduled to go to city council the following month.

The Top S&P 500 Stock of 2024 (So Far) Isn't Nvidia. Here's Where History Says the Soaring Stock Is Headed in 2025.

AP News Summary at 5:37 p.m. ESTOpposition Leader wants police to investigate murder plot claimGiants owners face a decision on how to mollify frustrated fans

Weber St. 68, Pepperdine 53US budget airlines are struggling. Will pursuing premium passengers solve their problems? DALLAS (AP) — Delta and United Airlines have become the most profitable U.S. airlines by targeting premium customers while also winning a significant share of budget travelers. That is squeezing smaller low-fare carriers like Spirit Airlines, which filed for bankruptcy protection on Monday. Some travel industry experts think Spirit’s troubles indicate less-wealthy passengers will have fewer choices and higher prices. Other discount airlines are on better financial footing but also are lagging far behind the full-service airlines when it comes to recovering from the COVID-19 pandemic. Most industry experts think Frontier and other so-called ultra-low-cost carriers will fill the vacuum if Spirit shrinks, and that there's still plenty of competition to prevent prices from spiking. Bitcoin ticks closer to $100,000 in extended surge following US elections NEW YORK (AP) — Bitcoin is jumping again, setting another new high above $99,000. The cryptocurrency has been shattering records almost daily since the U.S. presidential election, and has rocketed more than 40% higher in just two weeks. It's now at the doorstep of $100,000. Cryptocurrencies and related investments like crypto exchange-traded funds have rallied because the incoming Trump administration is expected to be more “crypto-friendly.” Still, as with everything in the volatile cryptoverse, the future is hard to predict. And while some are bullish, other experts continue to warn of investment risks. Supreme Court steps into fight over FCC's $8 billion subsidies for internet and phone services WASHINGTON (AP) — The Supreme Court has stepped into a major legal fight over the $8 billion a year the federal government spends to subsidize phone and internet services in schools, libraries and rural areas, in a new test of federal regulatory power. The justices on Friday agreed to review an appellate ruling that struck down as unconstitutional the Universal Service Fund. The Federal Communications Commission collects money from telecommunications providers, who then pass the cost on to their customers. The Biden administration appealed the lower court ruling, but the case probably won’t be argued until late March. At that point, the Trump administration will be in place and it is not clear whether it will take a different view of the issue. Stock market today: Wall Street gains ground as it notches a winning week and another Dow record Stocks closed higher on Wall Street, giving the market its fifth gain in a row and notching another record high for the Dow Jones Industrial Average. The S&P 500 rose 0.3% Friday. The Dow added 1%, and the Nasdaq composite tacked on 0.2%. Retailers had some of the biggest gains. Gap soared after reporting quarterly results that easily beat analysts' estimates. EchoStar fell after DirecTV called off its purchase of that company's Dish Network unit. European markets closed mostly higher and Asian markets ended mixed. Treasury yields held relatively steady in the bond market. Crude oil prices gained ground. Australia rejects Elon Musk's claim that it plans to control access to the internet MELBOURNE, Australia (AP) — An Australian Cabinet minister has rejected X Corp. owner Elon Musk’s allegation that the government intends to control all Australians' access to the internet through legislation that would ban young children from social media. Treasurer Jim Chalmers said on Friday that Musk’s criticism was “unsurprising” after the government introduced legislation to Parliament that would fine platforms including X up to $133 million for allowing children under 16 to hold social media accounts. The spat continues months of open hostility between the Australian government and the tech billionaire over regulators’ efforts to reduce public harm from social media. Parliament could pass the legislation as soon as next week. Oil company Phillips 66 faces federal charges related to alleged Clean Water Act violations LOS ANGELES (AP) — Oil company Phillips 66 has been federally indicted in connection with alleged violations of the Clean Water Act in California. The Texas-based company is accused of discharging hundreds of thousands of gallons of industrial wastewater containing excessive amounts of oil and grease. The U.S. Department of Justice announced the indictment on Thursday. Phillips is charged with two counts of negligently violating the Clean Water Act and four counts of knowingly violating the Clean Water Act. An arraignment date has not been set. A spokesperson for the company said it was cooperating with prosecutors. US regulators seek to break up Google, forcing Chrome sale as part of monopoly punishment U.S. regulators want a federal judge to break up Google to prevent the company from continuing to squash competition through its dominant search engine after a court found it had maintained an abusive monopoly over the past decade. The proposed breakup floated in a 23-page document filed late Wednesday by the U.S. Justice Department calls for Google to sell its industry-leading Chrome web browser and impose restrictions designed to prevent Android from favoring its search engine. Regulators also want to ban Google from forging multibillion-dollar deals to lock in its dominant search engine as the default option on Apple’s iPhone and other devices. New York judge rejects state efforts to shutter bitcoin mine over climate concerns NEW YORK (AP) — A New York judge has rejected an effort by state regulators to shutter a bitcoin mine over concerns about its greenhouse gas emissions. The decision will allow the Greenidge power plant to continue operating in the Finger Lakes region of the state. The state had previously found the gas-powered crypto mine ran afoul of a climate law intended to limit greenhouse gas emissions. But on Thursday, a state Supreme Court judge found Greenidge was entitled to a process to defend its continued operation. Environmental groups have protested the facility, which they allege is pumping emissions into the air while contaminating the nearby Seneca Lake. What you need to know about the proposed measures designed to curb Google's search monopoly U.S. regulators are proposing aggressive measures to restore competition to the online search market after a federal judge ruled that Google maintained an illegal monopoly. The sweeping set of recommendations filed late Wednesday could radically alter Google’s business. Regulators want Google to sell off its industry-leading Chrome web browser. They outlined a range of behavioral measures such as prohibiting Google from using search results to favor its own services such as YouTube, and forcing it to license search index data to its rivals. They're not going as far as to demand Google spin off Android, but are leaving that door open if the remedies don't work. Apple and Google face UK investigation into mobile browser dominance LONDON (AP) — A British watchdog says Apple and Google aren't giving consumers a genuine choice of mobile web browsers. The watchdog's report Friday recommends they face an investigation under new U.K. digital rules taking effect next year. The Competition and Markets Authority took aim at Apple, saying the iPhone maker’s tactics hold back innovation by stopping rivals from giving users new features like faster webpage loading. The CMA’s report also found that Apple and Google manipulate the choices given to mobile phone users to make their own browsers “the clearest or easiest option.” Apple said it disagreed with the findings.

Musk isn't helping Trump out of the goodness of his own heart. Brandon Bell/Pool/AP A news clip making the rounds Sunday morning had CNN’s Dana Bash talking with Chris Sununu, New Hampshire’s Republican governor, about Elon Musk’s potential conflicts of interest. Here, after all, we have a hecto-billionaire with massive federal contracts via SpaceX—and whose carmaker, Tesla, likely wouldn’t have survived without generous state and federal subsidies—serving as an advisor to an incoming president on how the government should be spending its money , or not. Sununu told Bash he liked that Musk is an “outsider”—an interesting choice of words—who is “not looking for anything.” When she challenged that notion, he responded, “The guy is worth $450 billion” and therefore is “so rich he’s removed from the potential financial influence.” “I don’t think he’s doing it for the money,” Sununu said. “He’s doing it for the bigger project and the bigger vision of America.” The exchange is worth a listen: BASH: One of the concerns is that Elon Musk has billions tied up in govt contracts. You don't see a conflict of interest?CHRIS SUNUNU: Everyone has a conflict of interestBASH: But that's a pretty big oneSUNUNU: He's so rich he's removed from the potential financial influence What this tells me is that Sununu doesn’t understand the mentality of excessive wealth and he probably shouldn’t be on the air talking about it. He’s correct, in one sense, that Musk is not doing it for the money. I mean, the guy could probably afford to buy Greenland. But “the greater project and the bigger vision”? That’s the sort of nonsense Col. Potter from the old TV series M.A.S.H. would have called “horse hockey”— among other things . Musk is doing this for the power —the opportunity to dominate his peers. Let’s not forget that joining forces with Trump put Musk’s wealth, at least on paper, on a very steep upward trajectory. I haven’t done the math, but I’m pretty sure he’s now the richest person who has ever lived on our planet. He doesn’t need money to buy stuff. He needs it to nourish his narcissism. I interviewed quite a few super-rich folks, and people in their close orbits, while researching my 2021 book , Jackpot , and we talked a lot about these kinds of matters. It became clear that, once a person attains a certain level of wealth, any further accumulation of assets is like a game. It’s all about score-keeping and social comparisons—and also maintaining one’s dynastic position by creating trusts to circumvent gift and estate taxes and pushing to maintain stupid loopholes like the discounted tax rate on carried interest, which even one private equity guy admitted to me was “bullshit,” though he was part of a group that made an annual pilgrimage to DC to lobby for it. Here’s a abridged snippet from one of my interviews with Richard Watts, an attorney in Southern California who serves as a consigliere for some of America’s wealthiest families. Here he was talking about a conference he’d just spoken at—an annual shindig hosted by Mitt Romney and attended by loads of Fortune 500 CEOs and billionaires with names you’d know, in addition to former presidents and senators and other power players. “I’m very well off, so I certainly don’t need to be working and doing all that stuff, and I’ve got a beautiful home down by the ocean. But when I spend the weekend with people that probably have a minimum net worth of $500 million, at some point I just have to leave, because you can feel in the discussion the measure is how big you are... In those situations it’s always about what spectacular thing have you done, invented, created: What do you do? “Well, I own 35 mobile home parks free and clear, and we built them, and we’re going green with all of them. And it’s really been a great, wonderful thing.” And the guy’s 40 years old, and that’s a true story... Now, if you’re Jamie Dimon, everybody kind of wants to see what you’re thinking and you know, “Hey, that’s a good guy. I want to be around him.” And then if it’s the governor of Maine, or let’s say it’s Mitt or it’s Paul Ryan, these are really interesting people. And the interesting thing is they kind of don’t want to have that discussion, but everyone has it with them. So, it’s like, “Hey Paul, since you’ve been out of the Speaker of the House, what is it you’re doing this year?” “Oh my god, I’m on the board of Fox News.” (And of course Murdoch was there lecturing as well.) And it’s just this feeling that the only measure in the room—I don’t mean that they always stay this way, I’m just saying when they group together—it’s about who’s got the biggest boat, and I can say that in a lot of different ways that are nasty, but the biggest boat is pretty quickly identified. One month prior to the election, Elon Musk’s estimated net worth was about $263 billion . Now, at year’s end, it is $437 billion . The “biggest boat” has been identified. It’s Elon and it ain’t even close and Musk would like to keep it that way and his relationship with Trump helps him do that. So Sununu can spare us the “greater project” nonsense. This is a dick-measuring contest, no more, no less.

NEW YORK (AP) — A slide for market superstar Nvidia on Monday knocked Wall Street off its big rally and helped drag U.S. stock indexes down from their records. The S&P 500 fell 0.6%, coming off its 57th all-time high of the year so far. The Dow Jones Industrial Average dipped 240 points, or 0.5%, and the Nasdaq composite pulled back 0.6% from its own record. Nvidia’s fall of 2.5% was by far the heaviest weight on the S&P 500 after China said it’s investigating the company over suspected violations of Chinese anti-monopoly laws. Nvidia has skyrocketed to become one of Wall Street’s most valuable companies because its chips are driving much of the world’s move into artificial-intelligence technology. That gives its stock’s movements more sway on the S&P 500 than nearly every other. Nvidia’s drop overshadowed gains in Hong Kong and for Chinese stocks trading in the United States on hopes that China will deliver more stimulus for the world’s second-largest economy. Roughly three in seven of the stocks in the S&P 500 also rose. The week’s highlight for Wall Street will arrive midweek when the latest updates on inflation arrive. Economists expect Wednesday’s report to show the inflation that U.S. consumers are feeling remained stuck at close to the same level last month. A separate report on Thursday, meanwhile, could show an acceleration in inflation at the wholesale level. They’re the last big pieces of data the Federal Reserve will get before its meeting next week on interest rates. The widespread expectation is still that the central bank will cut its main interest rate for the third time this year. The Fed has been easing its main interest rate from a two-decade high since September to offer more help for the slowing job market, after bringing inflation nearly all the way down to its 2% target. Lower interest rates can ease the brakes off the economy, but they can also offer more fuel for inflation. Expectations for a series of cuts from the Fed have been a major reason the S&P 500 has set so many all-time highs this year. “Investors should enjoy this rally while it lasts—there’s little on the horizon to disrupt the momentum through year-end,” according to Mark Hackett, chief of investment research at Nationwide, though he warns stocks could stumble soon because of how overheated they’ve gotten. On Wall Street, Interpublic Group rose 3.6% after rival Omnicom said it would buy the marketing and communications firm in an all-stock deal. The pair had a combined revenue of $25.6 billion last year. Omnicom, meanwhile, sank 10.2%. Macy’s climbed 1.8% after an activist investor, Barington Capital Group, called on the retailer to buy back at least $2 billion of its own stock over the next three years and make other moves to help boost its stock price. Super Micro Computer rose 0.5% after saying it got an extension that will keep its stock listed on the Nasdaq through Feb. 25, as it works to file its delayed annual report and other required financial statements. Earlier this month, the maker of servers used in artificial-intelligence technology said an investigation found no evidence of misconduct by its management or by the company’s board following the resignation of its public auditor . All told, the S&P 500 fell 37.42 points to 6,052.85. The Dow dipped 240.59 to 4,401.93, and the Nasdaq composite lost 123.08 to 19,736.69. In the oil market, a barrel of benchmark U.S. crude rallied 1.7% to settle at $68.37 following the overthrow of Syrian leader Bashar Assad, who sought asylum in Moscow after rebels. Brent crude, the international standard, added 1.4% to $72.14 per barrel. The price of gold also rose 1% to $2,685.80 per ounce amid the uncertainty created by the end of the Assad family’s 50 years of iron rule. In stock markets abroad, the Hang Seng jumped 2.8% in Hong Kong after top Chinese leaders agreed on a “moderately loose” monetary policy for the world’s second-largest economy. That’s a shift away from a more cautious, “prudent” stance for the first time in 10 years. A major planning meeting later this week could also bring more stimulus for the Chinese economy. U.S.-listed stocks of several Chinese companies climbed, including a 12.4% jump for electric-vehicle company Nio and a 7.4% rise for Alibaba Group. Stocks in Shanghai, though, were roughly flat. In Seoul, South Korea’s Kospi slumped 2.8% as the fallout continues from President Yoon Suk Yeol ’s brief declaration of martial law last week in the midst of a budget dispute. In the bond market, the yield on the 10-year Treasury rose to 4.19% from 4.15% late Friday. AP Business Writers Matt Ott and Elaine Kurtenbach contributed.Canadian Imperial Bank of Commerce stock rises Thursday, outperforms market

Mikaela Shiffrin suffers abrasion on hip during crash on final run of World Cup giant slalom

— BIRTH NAME: James Earl Carter, Jr. — BORN: Oct. 1, 1924, at the Wise Clinic in Plains, Georgia, the first U.S. president born in a hospital. He would become the first president to live for an entire century . — EDUCATION: Plains High School, Plains, Georgia, 1939-1941; Georgia Southwestern College, Americus, Georgia, 1941-1942; Georgia Institute of Technology, Atlanta, 1942-1943; U.S. Naval Academy, Annapolis, Maryland, 1943-1946 (class of 1947); Union College, Schenectady, New York, 1952-1953. — PRESIDENCY: Sworn-in as 39th president of the United States at the age of 52 years, 3 months and 20 days on Jan. 20, 1977, after defeating President Gerald R. Ford in the 1976 general election. Left office on Jan. 20, 1981, following 1980 general election loss to Ronald Reagan. — POST-PRESIDENCY: Launched The Carter Center in 1982. Began volunteering at Habitat for Humanity in 1984. Awarded Nobel Peace Prize in 2002. Taught for 37 years at Emory University, where he was granted tenure in 2019, at age 94. — OTHER ELECTED OFFICES: Georgia state senator, 1963-1967; Georgia governor, 1971-1975. — OTHER OCCUPATIONS: Served in U.S. Navy, achieved rank of lieutenant, 1946-53; Farmer, warehouseman, Plains, Georgia, 1953-77. — FAMILY: Wife, Rosalynn Smith Carter , married July 7, 1946 until her death Nov. 19, 2023. They had three sons, John William (Jack), James Earl III (Chip), Donnel Jeffrey (Jeff); a daughter, Amy Lynn; and 11 living grandchildren and 14 great-grandchildren. Source: Jimmy Carter Library & MuseumST. LOUIS (AP) — Jason Zucker scored a tiebreaking power-play goal with 9:30 remaining and the Buffalo Sabres notched their third straight victory by beating the St. Louis Blues 4-2 on Sunday. Jiri Kulich extended Buffalo’s lead with a breakaway goal that went between Blues goalie Jordan Binnington’s legs with 3:41 to play. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Get updates and player profiles ahead of Friday's high school games, plus a recap Saturday with stories, photos, video Frequency: Seasonal Twice a week

Automatic Data Processing Inc. stock rises Friday, still underperforms market— Oct. 1, 1924: James Earl Carter Jr. is born in Plains, Georgia, son of James Sr. and Lillian Gordy Carter. — June 1946: Carter graduates from the U.S. Naval Academy. — July 1946: Carter marries Rosalynn Smith, in Plains. They have four children, John William (“Jack”), born 1947; James Earl 3rd (“Chip”), 1950; Donnel Jeffrey (Jeff), 1952; and Amy Lynn, 1967. — 1946-1953: Carter serves in a Navy nuclear submarine program, attaining rank of lieutenant commander. — Summer 1953: Carter resigns from the Navy, returns to Plains after father’s death. — 1953-1971: Carter helps run the family peanut farm and warehouse business. — 1963-1966: Carter serves in the Georgia state Senate. — 1966: Carter tries unsuccessfully for the Democratic gubernatorial nomination. — November 1970: Carter is elected governor of Georgia. Serves 1971-75. — Dec. 12, 1974: Carter announces a presidential bid. Atlanta newspaper answers with headline: “Jimmy Who?” — January 1976: Carter leads the Democratic field in Iowa, a huge campaign boost that also helps to establish Iowa’s first-in-the-nation caucus. — July 1976: Carter accepts the Democratic nomination and announces Sen. Walter Mondale of Minnesota as running mate. — November 1976: Carter defeats President Gerald R. Ford, winning 51% of the vote and 297 electoral votes to Ford’s 240. — January 1977: Carter is sworn in as the 39th president of the United States. On his first full day in office, he pardons most Vietnam-era draft evaders. —September 1977: U.S. and Panama sign treaties to return the Panama Canal back to Panama in 1999. Senate narrowly ratifies them in 1978. — September 1978: Egyptian President Anwar Sadat, Israeli Prime Minister Menachem Begin and Carter sign Camp David accords, which lead to a peace deal between Egypt and Israel the following year. — June 15-18, 1979: Carter attends a summit with Soviet President Leonid Brezhnev in Vienna that leads to the signing of the SALT II treaty. — November 1979: Iranian militants storm the U.S. Embassy in Tehran, taking 52 hostages. All survive and are freed minutes after Carter leaves office in January 1981. — April 1980: The Mariel boatlift begins, sending tens of thousands of Cubans to the U.S. Many are criminals and psychiatric patients set free by Cuban leader Fidel Castro, creating a major foreign policy crisis. — April 1980: An attempt by the U.S. to free hostages fails when a helicopter crashes into a transport plane in Iran, killing eight servicemen. — Nov. 4, 1980: Carter is denied a second term by Ronald Reagan, who wins 51.6% of the popular vote to 41.7% for Carter and 6.7% to independent John Anderson. — 1982: Jimmy and Rosalynn Carter co-found The Carter Center in Atlanta, whose mission is to resolve conflicts, protect human rights and prevent disease around the world. — September 1984: The Carters spend a week building Habitat for Humanity houses, launching what becomes the annual Carter Work Project. — October 1986: A dedication is held for The Carter Presidential Center in Atlanta. The center includes the Carter Presidential Library and Museum and Carter Center offices. — 1989: Carter leads the Carter Center’s first election monitoring mission, declaring Panamanian Gen. Manuel Noriega’s election fraudulent. — May 1992: Carter meets with Mikhail and Raisa Gorbachev at the Carter Center to discuss forming the Gorbachev Foundation. — June 1994: Carter plays a key role in North Korea nuclear disarmament talks. — September 1994: Carter leads a delegation to Haiti, arranging terms to avoid a U.S. invasion and return President Jean-Bertrand Aristide to power. — December 1994: Carter negotiates tentative cease-fire in Bosnia. — March 1995: Carter mediates cease-fire in Sudan’s war with southern rebels. — September 1995: Carter travels to Africa to advance the peace process in more troubled areas. — December 1998: Carter receives U.N. Human Rights Prize on 50th anniversary of the Universal Declaration of Human Rights. — August 1999: President Bill Clinton awards Jimmy and Rosalynn Carter the Presidential Medal of Freedom. — September 2001: Carter joins former Presidents Ford, Bush and Clinton at a prayer service at the National Cathedral in Washington after Sept. 11 attacks. — April 2002: Carter’s book “An Hour Before Daylight: Memories of a Rural Boyhood” chosen as finalist for Pulitzer Prize in biography. — May 2002: Carter visits Cuba and addresses the communist nation on television. He is the highest-ranking American to visit in decades. — Dec. 10, 2002: Carter is awarded the Nobel Peace Prize for his “untiring effort to find peaceful solutions to international conflicts, to advance democracy and human rights, and to promote economic and social development.” — July 2007: Carter joins The Elders, a group of international leaders brought together by Nelson Mandela to focus on global issues. — Spring 2008: Carter remains officially neutral as Sens. Barack Obama and Hillary Rodham Clinton battle each other for the Democratic presidential nomination. — April 2008: Carter stirs controversy by meeting with the Islamic militant group Hamas. — August 2010: Carter travels to North Korea as the Carter Center negotiates the release of an imprisoned American teacher. — August 2013: Carter joins President Barack Obama and former President Bill Clinton at the 50th anniversary of the Rev. Martin Luther King Jr.’s “I Have A Dream” speech and the March on Washington. — Oct. 1, 2014: Carter celebrates his 90th birthday. — December 2014: Carter is nominated for a Grammy in the best spoken word album category, for his book “A Call To Action.” — May 2015: Carter returns early from an election observation visit in Guyana — the Carter Center’s 100th — after feeling unwell. — August 2015: Carter has a small cancerous mass removed from his liver. He plans to receive treatment at Emory Healthcare in Atlanta. — August 2015: Carter announces that his grandson Jason Carter will chair the Carter Center governing board. — March 6, 2016: Carter says an experimental drug has eliminated any sign of his cancer, and that he needs no further treatment. — May 25, 2016: Carter steps back from a “front-line” role with The Elders to become an emeritus member. — July 2016: Carter is treated for dehydration during a Habitat for Humanity build in Canada. — Spring 2018: Carter publishes “Faith: A Journey for All,” the last of 32 books. — March 22, 2019: Carter becomes the longest-lived U.S. president, surpassing President George H.W. Bush, who died in 2018. — September 18, 2019: Jimmy and Rosalynn Carter deliver their final in-person annual report at the Carter Center. — October 2019: At 95, still recovering from a fall, Carter joins the Work Project with Habitat for Humanity in Nashville, Tennessee. It’s the last time he works personally on the annual project. — Fall 2019-early 2020: Democratic presidential hopefuls visit, publicly embracing Carter as a party elder, a first for his post-presidency. — November 2020:The Carter Center monitors an audit of presidential election results in the state of Georgia, marking a new era of democracy advocacy within the U.S. — Jan. 20, 2021: The Carters miss President Joe Biden’s swearing-in, the first presidential inauguration they don’t attend since Carter’s own ceremony in 1977. The Bidens later visit the Carters in Plains on April 29. — Feb. 19, 2023: Carter enters home hospice care after a series of short hospital stays. — July 7, 2023: The Carters celebrate their 77th and final wedding anniversary. — Nov. 19, 2023: Rosalynn Carter dies at home, two days after the family announced that she had joined the former president in receiving hospice care. — Oct. 1, 2024 — Carter becomes the first former U.S. president to reach 100 years of age , celebrating at home with extended family and close friends. — Oct. 16, 2024 — Carter casts a Georgia mail ballot for Democratic presidential nominee Kamala Harris, having told his family he wanted to live long enough to vote for her. It marks his 21st presidential election as a voter. — Dec. 29, 2024: Carter dies at home.

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