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WALTHAM, Mass., Dec. 03, 2024 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced that, effective December 1, 2024, the company granted non-qualified stock options to purchase 8,400 shares of its common stock to one new employee under Xilio Therapeutics’ 2022 Inducement Stock Incentive Plan. The stock options have an exercise price of $1.09 per share, which is equal to the closing price of the company’s common stock on November 29, 2024. Each stock option will have a ten-year term and will vest as to 25% of the shares underlying the stock option on the first anniversary following commencement of employment, and the remaining 75% of the shares underlying each stock option will vest in 36 equal monthly installments thereafter, subject to continued service with the company or any of its subsidiaries through each applicable vesting date. The stock options are subject to the terms and conditions of Xilio Therapeutics’ 2022 Inducement Stock Incentive Plan, as well as the terms and conditions of the stock option agreement covering the grant and were made as an inducement material to the individual entering into employment with the company in accordance with Nasdaq Listing Rule 5635(c)(4). About Xilio Therapeutics Xilio Therapeutics is a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology (I-O) therapies with the goal of significantly improving outcomes for people living with cancer without the systemic side effects of current I-O treatments. The company is using its proprietary platform to advance a pipeline of novel, tumor-activated clinical and preclinical I-O molecules that are designed to optimize the therapeutic index by localizing anti-tumor activity within the tumor microenvironment, including tumor-activated cytokines, antibodies, bispecifics and immune cell engagers. Learn more by visiting www.xiliotx.com and follow us on LinkedIn ( Xilio Therapeutics, Inc .). This press release contains hyperlinks to information that is not deemed to be incorporated by reference in this press release. Investor and Media Contact: Scott Young Vice President, Investor Relations and Corporate Communications investors@xiliotx.comTable of ContentsAt a time when the (ASX: XJO) is close to all-time highs, it may be challenging to find compelling stocks at compelling values. Luckily, fund managers from Wilson Asset Management have pointed out two ASX shares that are growing rapidly and look compelling. The investment team that manages the ( ), are looking for stocks that are "the most compelling growth opportunities in the Australian market". In a recent update to investors, WAM nominated two that are seeing double-digit financial growth in percentage terms, giving them a strong outlook. Let's look at those two ideas below. Block Inc CDI ( ) WAM described Block as a business that offers a range of financial services and products, including Square, which helps businesses process transactions and achieve their growth aspirations. It has been a good time to own Block shares in recent times. The Block share price has risen more than 33% since the start of November 2024, as shown on the chart above. Some of those gains came after Block revealed its for the three months to September 2024. That update showed that grew by 19% year over year to US$2.25 billion. The ASX share's profit margins increased, with adjusted operating profit ( ) growing by 69% year over year, which was stronger than the market was expecting. WAM explained why it remains bullish on the payments company: We continue to expect Block to outperform its initial gross profit guidance for 2024 with a strong outlook for 2025 and also see a chance that the company enters the S&P 500 Index in the United States. Gentrack Group Ltd ( ) The other ASX growth share that WAM highlighted was Gentrack, a technology provider to many of the world's largest energy and water companies, as well as airports. The Gentrack share price has been on an incredible run this year, rising by 105% in 2024 to date, as shown on the chart above. It climbed more than 40% in November alone following the release of its for the 12 months to 30 September 2024. Gentrack's FY24 report included revenue growth of 25.5% thanks to strong growth in both the utilities and airports divisions, which beat market expectations. WAM revealed why its investment team is still positive on the ASX tech share: We remain positive on Gentrack Group and the outlook for the company and believe the company's strong cash position can allow the business to make earnings accretive acquisitions. Time will tell whether these positive outlooks translate into further investment gains.

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ZAYN Malik has broken his silence after leaving fans devastated by cancelling a sell-out gig just minutes before he was due to take to the stage. The Former One Direction star was due to perform at a packed-out O2 City Hall in Newcastle on Tuesday night. Fans were eagerly waiting for the Stairway to the Sky set to get underway when it was announced on the tannoy the show had been cancelled. A spokesperson speaking from the stage said the show would not be going ahead. They said: "We apologise for the late notice. It was his fervent hope that he would be able to continue with the show. This is no longer possible. "Please contact your point of purchase for details of reschedules and refunds. If you have parents or guardians collecting you please stay within the auditorium and wait to be collected." read more on Zayn Malik Taking to Instagram , the 31-year-old singer wrote an explanation on his stories: He wrote: "I'm so sorry to do this but my voice just isn't there at all tonight and without it, there's no show. "I'm truly sorry to let you down, especially at such short notice...I held onto hope until the very last moment. "I'm hopeful with some rest tonight I'll be back on stage tomorrow. Most read in Music "My deepest apologies Newcastle love you all xx." FLOODS OF TEARS Devastated fans were seen streaming out of the O2 City Hall in floods of tears. Courtni Clarke, 19, had queued for 36 hours to make sure she got to the front of the standing section to get as close as possible to her favourite singer. But, despite the tears on her face, the bar worker from Leeds says that she is only concerned about Zayn's health . She said: "I hope he's ok. One of the security guards told us they don't even know if he made it here. "It's a disappointment but also a worry. I'm a very, very big fan of Zayn. We got no information of what happened." Clarke and other fans spoke about how they paid £150 for tickets plus additional costs for travel to get to the venue. She called the last-minute cancellation a "deep wound" after seeing the other members of One Direction singing on their solo tours and now no longer being able to see Liam sing live. Kitty Heidt, 20, a law student at Durham University arrived at 7pm to get into the venue. "We were very excited to get in," she said. "If he didn't show up, they should have told us. We waited an hour inside anything before it was cancelled." "It's a waste of time. I'm upset and disappointed," another fan said. Others defended the singer saying, "A lot of fans care more about them seeing him than his well being. "I'm happy to miss it as long as he's okay." Zayn is set to wrap up his tour in Edinburgh in just a few days. READ MORE SUN STORIES The US leg of the tour was postponed after the death of his former bandmate Liam Payne who he has paid tribute to at previous UK shows in Manchester and Leeds. Liam tragically died on October 16 after falling from a balcony at his hotel in Argentina.Renowned journalist and editor-in-chief of the New Crusading Guide , Abdul Malik Kweku Baako Jnr., has publicly declared his support for the New Patriotic Party (NPP) ahead of the December 7 general elections. In a passionate message shared on social media, Baako creatively tied his surname to the party’s position on the ballot, urging Ghanaians to cast their votes for the NPP. “My name is BAAKO. I will vote for Number ONE (BAAKO) on the Presidential Ballot on December 7th! I appeal to the good people of Ghana to do the same! I pray Number ONE (BAAKO) triumphs. FINGERS CROSSED!” he wrote, expressing hope for a victory that aligns with his vision for the country’s future. Acknowledging the expected backlash from his public endorsement, Baako remained undeterred, expressing his readiness to face any criticism. “I know the usual suspects would come raining insults and threaten brimstone and fire here! I will tolerate their predictably robotic character assassinations and personality attacks. Blocking is alien to my political and communication DNA!” he said, maintaining his stance despite the anticipated vitriol. Baako, known for his resilience in the face of adversity, reaffirmed his commitment to free speech, a cornerstone of democracy. “I have the shock absorbers to contain their legendary nuisance! Their political antecedents did worse to me. All I would say is that FREE SPEECH is not a CRIME!” he concluded, addressing potential detractors with a defiant call for the protection of democratic expression.Stocks Settle Mixed as Nasdaq 100 Posts New Record High

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NEW YORK (AP) — U.S. stocks tiptoed to more records amid a mixed Tuesday of trading, tacking a touch more onto what’s already been a stellar year so far. The S&P 500 edged up by 2 points, or less than 0.1%, to set an all-time high for the 55th time this year. It’s climbed in 10 of the last 11 days and is on track for one of its best years since the turn of the millennium. The Dow Jones Industrial Average slipped 76 points, or 0.2%, while the Nasdaq composite added 0.4% to its own record set a day earlier. AT&T rose 4.6% after it boosted its profit forecast for the year. It also announced a $10 billion plan to send cash to its investors by buying back its own stock, while saying it expects to authorize another $10 billion of repurchases in 2027. On the losing end of Wall Street was U.S. Steel, which fell 8%. President-elect Donald Trump reiterated on social media that he would not let Japan’s Nippon Steel take over the iconic Pennsylvania steelmaker. Nippon Steel announced plans last December to buy the Pittsburgh-based steel producer for $14.1 billion in cash, raising concerns about what the transaction could mean for unionized workers, supply chains and U.S. national security. Earlier this year, President Joe Biden also came out against the acquisition. Tesla sank 1.6% after a judge in Delaware reaffirmed a previous ruling that the electric car maker must revoke Elon Musk’s multibillion-dollar pay package. The judge denied a request by attorneys for Musk and Tesla’s corporate directors to vacate her ruling earlier this year requiring the company to rescind the unprecedented pay package. All told, the S&P 500 rose 2.73 points to 6,049.88. The Dow fell 76.47 to 44,705.53, and the Nasdaq composite gained 76.96 to 19,480.91. In the bond market, Treasury yields held relatively steady after a report showed U.S. employers were advertising slightly more job openings at the end of October than a month earlier. Continued strength there would raise optimism that the economy could remain out of a recession that many investors had earlier worried was inevitable. The yield on the 10-year Treasury rose to 4.23% from 4.20% from late Monday. Yields have seesawed since Election Day amid worries that Trump’s preferences for lower tax rates and bigger tariffs could spur higher inflation along with economic growth. But traders are still confident the Federal Reserve will cut its main interest rate again at its next meeting in two weeks. They’re betting on a nearly three-in-four chance of that, according to data from CME Group. Story continues below video Lower rates can give the economy more juice, but they can also give inflation more fuel. The key report this week that could guide the Fed’s next move will arrive on Friday. It’s the monthly jobs report , which will show how many workers U.S. employers hired and fired during November. It could be difficult to parse given how much storms and strikes distorted figures in October. Based on trading in the options market, Friday’s jobs report appears to be the biggest potential market mover until the Fed announces its next decision on interest rates Dec. 18, according to strategists at Barclays Capital. In financial markets abroad, the value of South Korea’s currency fell 1.1% against the U.S. dollar following a frenetic night where President Yoon Suk Yeol declared martial law and then later said he’d lift it after lawmakers voted to reject military rule. Stocks of Korean companies that trade in the United States also fell, including a 1.6% drop for SK Telecom. Japan’s Nikkei 225 jumped 1.9% to help lead global markets. Some analysts think Japanese stocks could end up benefiting from Trump’s threats to raise tariffs , including for goods coming from China . Trade relations between the U.S. and China took another step backward after China said it is banning exports to the U.S. of gallium, germanium, antimony and other key high-tech materials with potential military applications. The counterpunch came swiftly after the U.S. Commerce Department expanded the list of Chinese technology companies subject to export controls to include many that make equipment used to make computer chips, chipmaking tools and software. The 140 companies newly included in the so-called “entity list” are nearly all based in China. In China, stock indexes rose 1% in Hong Kong and 0.4% in Shanghai amid unconfirmed reports that Chinese leaders would meet next week to discuss planning for the coming year. Investors are hoping it may bring fresh stimulus to help spur growth in the world’s second-largest economy. In France, the CAC 40 rose 0.3% amid continued worries about politics in Paris , where the government is battling over the budget. AP Business Writers Yuri Kageyama and Matt Ott contributed.Texas Attorney General Ken Paxton has launched an investigation into the Global Alliance for Responsible Media over allegations of an anticompetitive boycott targeting social media platforms, including Elon Musk ’s X. The investigation comes on the heels of an antitrust lawsuit filed by X in August, accusing GARM and its suburbanization, the World Federation of Advertisers, of orchestrating a coordinated boycott to withhold advertising revenue from platforms that do not adhere to GARM’s “Brand Safety Standards.” The investigation seeks to determine whether the groups violated antitrust laws by colluding to disadvantage platforms such as X and Rumble, a video-sharing platform favored by conservatives. In a statement , Paxton criticized the Biden administration as failing to enforce antitrust laws against its perceived political allies. "Trade organizations and companies cannot collude to block advertising revenue from entities they wish to undermine,” Paxton said, adding that such practices threaten free market competition. X’s lawsuit, filed in federal district court in Texas, alleges that GARM members, including Mars, CVS, Unilever, and Danish energy firm Orsted, acted in concert to enforce brand safety standards through a “naked restraint of trade” at the expense of social media platforms. The suit also claims that these actions were not in the advertisers’ individual economic interests but were instead part of a collective effort to pressure platforms such as X into compliance. Rumble joined X in the lawsuit, accusing GARM of imposing “one-size-fits-all” standards that led to boycotts of alternative platforms. Both companies are seeking an injunction to prevent further coordination among advertisers, as well as damages and legal fees. Investigation follows GARM's downfall The controversy surrounding GARM reached a tipping point in August when Musk’s lawsuit prompted WFA to announce GARM's shutdown . In a statement, WFA described GARM as a "not-for-profit initiative" and blamed its closure on a “distraction” caused by allegations of collusion. GARM was originally established in 2019 following the Christchurch mosque shootings in New Zealand to promote transparency and responsible advertising in digital media. However, critics, including Musk, argued that its brand safety standards became a tool for censorship and anticompetitive practices. X alleged that GARM members “abruptly and in lockstep” pulled advertising in 2023 over concerns about hate speech on the platform. Musk, who purchased X when it was Twitter in 2022 to promote free speech, faced significant backlash from advertisers as the platform saw increased scrutiny over its content moderation policies. Paxton’s investigation adds momentum to legal challenges against WFA and GARM, which are already facing scrutiny from Congress. The House Judiciary Committee previously found evidence suggesting GARM organized boycotts and used indirect tactics to target disfavored platforms and content creators. X CEO Linda Yaccarino has pointed to the committee’s findings as evidence of GARM’s alleged collusion, saying its actions "demonetized and limited choices for consumers." As Paxton’s office reviews WFA’s activities, the investigation underscores growing concerns about the influence of international advertising groups on free speech and market competition. The outcome could have far-reaching consequences for the advertising industry and its role in shaping online discourse. It’s still a major problem — Elon Musk (@elonmusk) CLICK HERE TO READ MORE FROM THE WASHINGTON EXAMINER Musk has continued to call attention to what he describes as a systemic problem. "It’s still a major problem,” he posted on X in response to Paxton’s announcement.

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High school recruiting isn't the only way to build a winner in the transfer portal era

TALLAHASSEE, Fla. (AP) — Luke Kromenhoek threw for 209 yards and tossed three touchdown passes as Florida State halted a six-game losing streak and routed Charleston Southern 41-7 on Saturday. Kromenhoek completed 13 of 20 passes in his first college start, including a 71-yard touchdown pass to Ja’Khi Douglas, as the Seminoles (2-9) won for the first time since Sept. 21. The true freshman also connected with Amaree Williams for a 4-yard TD and Hykeem Williams for a 10-yard TD. Florida State had the nation’s lowest scoring offense at 13.3 points. The Seminoles hadn’t scored more than 21 points or surpassed the 300-yard mark in 2024. But Florida State overwhelmed FCS Charleston Southern (1-11), accumulating 415 offensive yards. Kaleb Jackson completed 22 of 32 passes for 218 yards, including a 7-yard touchdown pass to Landon Sauers, and an interception for the Buccaneers. The takeaway Charleston Southern: While the Buccaneers found some success through the air, they couldn’t sustain drives and managed just 57 rushing yards on 29 carries. Florida State: The Seminoles picked up a season-best 176 rushing yards, scoring 17 points in the second quarter and 14 points in the third quarter to take control. Up next Charleston Southern’s season is over. Florida State plays host to Florida on Nov. 30. AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football . Sign up for the AP’s college football newsletter: https://apnews.com/cfbtop25