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(BPT) - Cerebral palsy (CP) is a neurodevelopmental disorder affecting movement and posture that begins in early childhood development. It is the most common cause of motor disability in children, affecting about one in 345 children in the United States. It may happen as a result of lack of oxygen during or around birth, stroke, infection, a problem with metabolism or other problems that cause injury or affect the development of parts of the brain involved in movement control in the first few years of life. CP is a permanent condition, affecting a person for their entire life. People living with CP typically have motor problems, which may include spasticity (abnormal muscle tightness), dyskinesia (uncontrolled movements) or ataxia (poor muscle control), and many people have a mix of these motor disorders. Dyskinesia due to CP (DCP) is one of the most disabling forms of CP and impacts approximately 10% to 20% of people living with CP. According to the Cerebral Palsy Foundation (CPF), the combination of irregular and unpredictable movements (chorea) and twisting and repeating movements (dystonia) often disrupt activities and cause significant functional impairment, including the ability to maintain balance, walk or fine motor control. Heather Riordan, M.D., Neurologist and Movement Disorders Specialist, Director of the Phelps Center for Cerebral Palsy at the Kennedy Krieger Institute, discusses the symptoms of chorea and impact on patients in a video shared on the CPF website . About 30% of people with DCP are affected mostly by these involuntary and irregular movements (chorea), while dystonia is the predominant motor finding in the remaining 70%. However, it is common for both chorea and dystonia movements to be present together. For people living with DCP, these movements can occur in any region of the body, including the arms and legs, torso and face and may vary in severity. They are often triggered or made worse by stimulation or stress. Because dyskinesia can occur at rest and/or when actively using the body, the problems with movement are very burdensome in day-to-day living, with discomfort and pain affecting the quality of life for people and their caregivers. Jen Lyman, mom to a son with DCP, highlights how dyskinesia makes communicating more difficult. "The most difficult thing about dyskinesia is watching my son struggle to do things that he wants to do, but the extra movements get in the way...special things, such as using a touch screen to video chat with his grandmother, are nearly impossible despite his best efforts to use his hands and fingers. Something so simple, yet so special for him should be effortless." DCP has a wide-ranging impact on the individual, including lifelong challenges with movement, a higher risk of other medical issues, a higher rate of mental health challenges and difficulties with communication. "Those of us who have the privilege to serve patients with dyskinetic, hyperkinetic or mixed cerebral palsy see the functional impact of this very challenging type of tone every day," said Susan Biffl, M.D., Rehabilitation Medicine Specialist at Rady Children's Hospital-San Diego and Assistant Professor at UC San Diego School of Medicine. "Patients face challenges with self-care, independence, mobility, communication, fine motor skills that affect occupational and recreational activities, swallowing, social interactions and even sleep. As this tone is variable, it is much more challenging to treat than more consistent tone issues, such as spasticity." There are currently no Food and Drug Administration-approved treatments for DCP. Dystonia and chorea are often managed separately as they respond differently to various treatments, which can make treatment challenging. Most drugs being investigated for DCP have focused on dystonia, and more research is needed to determine potential treatments for chorea. New treatment options are needed to help manage these movement disorders and improve daily function and quality of life for those affected. "After 20 years of caring for individuals with cerebral palsy, I continue to find those with dyskinetic cerebral palsy among the most challenging to treat, largely due to the limited effectiveness of available pharmacologic options," said Joyce Oleszek, M.D., Professor, Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine. "There is an urgent need for more robust evidence to support pharmacologic treatments for this condition, given its profound impact on function, comfort and quality of life." Clinical studies are important in the development of treatment options, allowing researchers to evaluate the safety and effectiveness of new medicines. The data from clinical studies are used to determine if an investigational treatment can be approved for use to treat certain disorders. There are ongoing clinical studies evaluating potential treatments for DCP, including one for chorea. Neurocrine Biosciences is conducting the clinical study, a Phase 3, randomized, double-blind placebo-controlled study investigating the study drug, valbenazine, for the treatment of DCP. The clinical study is currently enrolling children, adolescents and adults six to 70 years of age who have been diagnosed with DCP. "The Cerebral Palsy Foundation is excited to partner with Neurocrine Biosciences on this study," said Rachel Byrne, Executive Director of the Cerebral Palsy Foundation. "We are proud to support strong research that can potentially bring meaningful change to the lives of those living with cerebral palsy." If you or someone you know may be eligible for this research study, please visit the study website for additional information here: . Krigger KW. Cerebral palsy: a review. . 2006;73(1):91-100. Michael-Asalu A, Taylor G, Campbell H, Lelea LL, Kirby RS. Cerebral palsy: diagnosis, epidemiology, genetics, and clinical update. Adv Pediatr2019;66:189-208. doi:10.1016/j.yapd.2019.04.002 Monbaliu E, Himmelmann K, Lin JP, et al. Clinical presentation and management of dyskinetic cerebral palsy. 2017;16(9):741-749. doi:10.1016/S1474-4422(17)30252-1 Christine C, Dolk H, Platt MJ, Colver A, Prasauskiene A, Krägeloh-Mann I; SCPE Collaborative Group. Recommendations from the SCPE collaborative group for defining and classifying cerebral palsy. 2007;109:35-38. doi:10.1111/j.1469-8749.2007.tb12626.x Lumsden DE, Crowe B, Basu A, et al. Pharmacological management of abnormal tone and movement in cerebral palsy. . 2019;104(8):775-780. doi:10.1136/archdischild-2018-316309 Monbaliu E, de Cock P, Ortibus E, Heyrman L, Klingels K, Feys H. Clinical patterns of dystonia and choreoathetosis in participants with dyskinetic cerebral palsy. Dyskinetic cerebral palsy. Cerebral Palsy Foundation. Published December 20, 2022. Accessed October 29, 2024. Himmelmann K, Hagberg G, Wiklund LM, Eek MN, Uvebrant P. Dyskinetic cerebral palsy: a population-based study of children born between 1991 and 1998. 2007;49(4):246-251. doi:10.1111/j.1469-8749.2007.00246.x Masson R, Pagliano E, Baranello G. Efficacy of oral pharmacological treatments in dyskinetic cerebral palsy: a systematic review. . 2017; 59:1237-1248. doi:10.1111/dmcn.13532 Adults & adolescence. Cerebral Palsy Foundation. Accessed November 13, 2024. Communication. Cerebral Palsy Foundation. Accessed November 13, 2024. © 2024 Neurocrine Biosciences, Inc. All Rights Reserved. CAP-NBI-US-0115 12/2024 NBI-98854-DCP3018_11DecMatRelease_v1.0_25November2024WOODLAND PARK, N.J. , Nov. 26, 2024 /PRNewswire/ -- Anterix (NASDAQ: ATEX ) Chief Operating Officer Ryan Gerbrandt will participate in a panel discussion related to the 900 MHz private wireless broadband revolution and its impact on helping our nation's utilities transform critical infrastructure. This panel will be held on December 5, 2024 , from 2:30 p.m. - 3:20 p.m. , during Janney's 2nd Annual Clean Energy Investment Symposium, taking place in New Orleans, LA . Additionally, Anterix Vice Chairman Tom Kuhn will deliver keynote remarks for the symposium at 7:30 p.m. on December 4 at the National WWII Museum. This keynote address will cover a range of strategic challenges and opportunities for utilities and critical infrastructure. Anterix will also host one-on-one meetings with interested investors during the event. Please contact your Janney representative to schedule a meeting. Shareholder Contact Natasha Vecchiarelli Vice President, Investor Relations & Corporate Communications Anterix 973-531-4397 [email protected] About Anterix At Anterix, we partner with leading utilities and technology companies to harness the power of 900 MHz broadband for modernized grid solutions. Leading an ecosystem of more than 100 members, we offer utility-first solutions to modernize the grid and solve the challenges that utilities are facing today. As the largest holder of licensed spectrum in the 900 MHz band (896-901/935-940 MHz) throughout the contiguous United States , plus Alaska , Hawaii , and Puerto Rico , we are uniquely positioned to enable private wireless broadband solutions that support cutting-edge advanced communications capabilities for a cleaner, safer, and more secure energy future. To learn more and join the 900 MHz movement, please visit www.anterix.com . SOURCE Anterix Inc.
The highlighted “Risky Drive” label blared out from my wife’s driving history on Life360. I chuckled at my type-A personality. The ex-EMS wife is not known for being an erratic driver. I also know that she was riding her bicycle during the trip which was cataloged as a “Risky Drive.” She was getting a few miles in before dark at the Susquehanna Valley Mall parking lot. The black line that indicated her “driving” route crisscrossed and backed over itself many times around the mall building. For all who are locals, we know that the mall is unfortunately and generally rather quiet, aside from the medical facility aspects. The traffic is usually low around the building and is probably safer to ride a bike there than on the road. That the tracking app is inaccurate and fallible is commonplace. Even if the app were reliable, does it have a healthy place in our lives? In our children’s lives? What does tracking someone do to a relationship? It is common for family units to use Life360 to keep tabs on one another — particularly, when teenagers start driving. This enables parents to monitor speed and location. It is also used for parents’ peace of mind to know that their new driver made it to their destination. However, sometimes family members can go a little bit overboard in monitoring and surveilling one another. By doing that, faith and trust are removed from the child-parent relationship and placed into the technology. This holds true for any relationship in which one or all parties are keeping tabs on one another. This removes trust from the equation because you can just look at your phone to see someone’s location. Your children go to school all day. While they are there, they are on camera, observed by police officers and their usage of school laptops is monitored. That is a lot of pressure for young folks to contend with while attempting to obtain an education. The learning environment is also one of surveillance. When the school day is finally over (you remember how long a school day took when you were a kid) the children leave school and are still monitored with tracking apps, the school laptops that they use for homework and cameras in stores or the streets. They can’t escape the pressure of being watched. Not even when their long workday is done, and they just want to go home and relax. That all sounds unnecessarily stressful. Children being tracked also removes opportunities for choice and thus growth. If a child knows their parents will see where he or she are always, they do not have the chance to make a choice. The student will not have the option to blow off soccer practice or not come straight home because of being watched. The kids are not making the conscious choice to stay at practice or come right home, they just must. This robs them of the chance to make a choice, including the “right” choice. If children do not learn how to make choices while in their parents’ care they will be lost when they enter the real world. I must say that I do use Life360 almost every day to see where my loved ones are, generally as a matter of convenience. I get that. It’s helpful and can offer some piece of mind sometimes. However, depending on the type of usage among family groups and friends, the effects of Life360 can be very harmful. I’m sure we have all heard the phrase, “Trust is the foundation of a good relationship.” Tracking people is a modern way of removing that crucial component of the relationship. So, maybe next time, instead of just looking to see where your spouse or kid is on your phone, use your phone to call them and ask how their day is going. Lydia Moore lives in Selinsgrove.
The incident has also shed light on the broader issue of transparency in the workplace. While many companies have policies in place to protect the confidentiality of salary information, the lack of transparency can sometimes lead to disparities in pay and hinder employees' ability to advocate for fair compensation. In an era where discussions around pay equity and transparency are becoming increasingly prevalent, the incident serves as a reminder of the challenges that employees face in navigating these issues within their organizations.In response to these concerns, the Chinese Ministry of Foreign Affairs reassured the international community that the airspace restrictions were not targeted at any specific country or region. Spokesperson Wang Wenbin emphasized that China remained committed to maintaining peace and stability in the region and would continue to uphold the principles of non-interference in the internal affairs of other countries.
(BPT) - Cerebral palsy (CP) is a neurodevelopmental disorder affecting movement and posture that begins in early childhood development. It is the most common cause of motor disability in children, affecting about one in 345 children in the United States. It may happen as a result of lack of oxygen during or around birth, stroke, infection, a problem with metabolism or other problems that cause injury or affect the development of parts of the brain involved in movement control in the first few years of life. CP is a permanent condition, affecting a person for their entire life. People living with CP typically have motor problems, which may include spasticity (abnormal muscle tightness), dyskinesia (uncontrolled movements) or ataxia (poor muscle control), and many people have a mix of these motor disorders. Dyskinesia due to CP (DCP) is one of the most disabling forms of CP and impacts approximately 10% to 20% of people living with CP. According to the Cerebral Palsy Foundation (CPF), the combination of irregular and unpredictable movements (chorea) and twisting and repeating movements (dystonia) often disrupt activities and cause significant functional impairment, including the ability to maintain balance, walk or fine motor control. Heather Riordan, M.D., Neurologist and Movement Disorders Specialist, Director of the Phelps Center for Cerebral Palsy at the Kennedy Krieger Institute, discusses the symptoms of chorea and impact on patients in a video shared on the CPF website . About 30% of people with DCP are affected mostly by these involuntary and irregular movements (chorea), while dystonia is the predominant motor finding in the remaining 70%. However, it is common for both chorea and dystonia movements to be present together. For people living with DCP, these movements can occur in any region of the body, including the arms and legs, torso and face and may vary in severity. They are often triggered or made worse by stimulation or stress. Because dyskinesia can occur at rest and/or when actively using the body, the problems with movement are very burdensome in day-to-day living, with discomfort and pain affecting the quality of life for people and their caregivers. Jen Lyman, mom to a son with DCP, highlights how dyskinesia makes communicating more difficult. "The most difficult thing about dyskinesia is watching my son struggle to do things that he wants to do, but the extra movements get in the way...special things, such as using a touch screen to video chat with his grandmother, are nearly impossible despite his best efforts to use his hands and fingers. Something so simple, yet so special for him should be effortless." DCP has a wide-ranging impact on the individual, including lifelong challenges with movement, a higher risk of other medical issues, a higher rate of mental health challenges and difficulties with communication. "Those of us who have the privilege to serve patients with dyskinetic, hyperkinetic or mixed cerebral palsy see the functional impact of this very challenging type of tone every day," said Susan Biffl, M.D., Rehabilitation Medicine Specialist at Rady Children's Hospital-San Diego and Assistant Professor at UC San Diego School of Medicine. "Patients face challenges with self-care, independence, mobility, communication, fine motor skills that affect occupational and recreational activities, swallowing, social interactions and even sleep. As this tone is variable, it is much more challenging to treat than more consistent tone issues, such as spasticity." There are currently no Food and Drug Administration-approved treatments for DCP. Dystonia and chorea are often managed separately as they respond differently to various treatments, which can make treatment challenging. Most drugs being investigated for DCP have focused on dystonia, and more research is needed to determine potential treatments for chorea. New treatment options are needed to help manage these movement disorders and improve daily function and quality of life for those affected. "After 20 years of caring for individuals with cerebral palsy, I continue to find those with dyskinetic cerebral palsy among the most challenging to treat, largely due to the limited effectiveness of available pharmacologic options," said Joyce Oleszek, M.D., Professor, Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine. "There is an urgent need for more robust evidence to support pharmacologic treatments for this condition, given its profound impact on function, comfort and quality of life." Clinical studies are important in the development of treatment options, allowing researchers to evaluate the safety and effectiveness of new medicines. The data from clinical studies are used to determine if an investigational treatment can be approved for use to treat certain disorders. There are ongoing clinical studies evaluating potential treatments for DCP, including one for chorea. Neurocrine Biosciences is conducting the clinical study, a Phase 3, randomized, double-blind placebo-controlled study investigating the study drug, valbenazine, for the treatment of DCP. The clinical study is currently enrolling children, adolescents and adults six to 70 years of age who have been diagnosed with DCP. "The Cerebral Palsy Foundation is excited to partner with Neurocrine Biosciences on this study," said Rachel Byrne, Executive Director of the Cerebral Palsy Foundation. "We are proud to support strong research that can potentially bring meaningful change to the lives of those living with cerebral palsy." If you or someone you know may be eligible for this research study, please visit the study website for additional information here: . © 2024 Neurocrine Biosciences, Inc. All Rights Reserved. CAP-NBI-US-0115 12/2024 NBI-98854-DCP3018_11DecMatRelease_v1.0_25November2024Using a length of sturdy wire and a small hook fashioned from a paperclip, the firefighter ingeniously put together a simple yet effective retrieval device. With skilled precision, he carefully maneuvered the tool through the narrow openings of the drain, guided by the encouraging cheers and support of the gathered crowd.
Two Super Bowl finalists squaring off in their annual battle where both teams have storied histories? You bet. Foxboro (8-3) and Mansfield (8-3) collide in Mansfield at 10 a.m. for the 93rd annual meeting between the two foes, with the Warriors holding bragging rights following a 30-17 win last year as they again play for Davenport Division rights in the Hockomock League. Both sides aren’t going to let up and play it safe for the Super Bowl next week, that’s for sure. Foxboro will go with its patented running game on Ben Angelini’s legs, while mixing in Mike Marcucella’s passing ability. The Hornets will do the same with Sean McCoy running the ball and Tommy Vallett passing. Both sides are similar in their offensive styles and their desire to be balanced while being explosive on the ground. Both defenses know exactly what they’re in for when it comes to who is on the other side of the field. Mansfield dominated the run last week, and Foxboro walked it off to earn the Warriors’ Super Bowl bid, so energy and confidence for both is the highest it has been all season. There won’t be many surprises in this good, old-fashioned rivalry with some edge to it. This will be a fun one.
Pakistan developing missiles that eventually could hit US: White House official
In an exciting turn of events for Beijing Guoan football club, former Barcelona manager Quique Setién has officially been announced as the new head coach, signaling a new era for the team. Setién brings a wealth of coaching experience and tactical knowledge, having previously managed top clubs in Spain.A may not be the gift Americans had on their list this holiday season. But the . A shutdown became more likely after President-elect opposed a reached Wednesday to keep through mid-March. Complicating an already complex situation: Trump wants Congress to because the current debt limit suspension . An agreement would give the incoming administration time to use to pay the bills. A question possibly on the minds of the 68 million Americans currently getting : What happens to the Social Security Administration during a government shutdown? Will recipients still get benefits checks? Here's what to know. During a government shutdown, some federal agencies continue their work because at least some of their workers are considered “essential” to continue activities such as air traffic control, border protection, law enforcement, in-hospital medical care, and power grid maintenance, notes the nonprofit, nonpartisan . Among those agencies and programs that continue on because some of their mandatory spending is not subject to annual appropriations by Congress: Medicare, Medicaid and, yes, Social Security. Social Security has "dedicated funding, so it's outside of the budget process," said Craig Copeland, director of wealth benefits research at the . "All that money is there to paid (out). It doesn't have to be appropriated. ... You're still going to get your checks." That means retirement and disability benefits including (SSI) payments will continue to go out. Also unaffected by a shutdown: military veterans' benefits, and medical care, and food benefits under the Supplemental Nutrition Assistance Program (SNAP). The Social Security Administration has a contingency plan for shutdowns. In a letter to the director of the Office of Management and Budget three months ago, the described its 2025 fiscal year plan for a potential federal government shutdown. That coincided with a potential mid-September shutdown, which was avoided by an . (That agreement expires on Friday.) The SSA details how it will "continue activities critical to our direct-service operations and those needed to ensure accurate and timely payment of benefits .... (and) will cease activities not directly related to the accurate and timely payment of benefits or not critical to our direct-service operations." The plan, signed by Chad Poist, the SSA's deputy commissioner for the budget, finance and management, cites from the Department of Justice to the Office of Management and Budget that any other government activities needed to disburse Social Security benefits are allowed during a "lapse in appropriations." The SSA's continued activities include processing benefits applications, issuing new and replacement Social Security cards, and information technology work needed for daily processing activities, fraud protection, and other applications. Some discontinued activities during a shutdown include benefit verifications, earnings record corrections and updates unrelated to adjudication of benefits, and IT enhancement activities. "Some of the (SSA) workers could be furloughed until this is resolved, because some of those services are funded differently than the way the benefits are," Copeland said. He suggests anyone who has an appointment to start benefits or to handle benefit calculations to make sure their appointments will happen or need to be rescheduled. "Appointments ... could be impacted," he said. Those recipients whose birthdates range from the 21st to the 31st of the month are scheduled to get a check on Dec. 24, according to the . The January SSI payment is scheduled to go out Dec. 31. The next checks would be Jan. 3 for recipients who began receiving Social Security before May 1997. Those who get both Social Security & SSI will get Social Security paid on Jan. 3 and SSI on Jan. 1, according to . Checks go out on Jan. 8 for those whose birthdates are from the 1st to 10th of the month and Jan. 15 for those whose birthdates are from the 11th to 20th. ,
( MENAFN - GetNews) Lumo Therapy, a groundbreaking innovation in personal wellness, is now available to customers seeking effective, non-invasive light therapy solutions. Designed with advanced technology, Lumo Therapy harnesses the proven benefits of light therapy to help alleviate seasonal affective disorder (SAD), enhance mood, and boost energy levels. This cutting-edge device is currently being offered with an exclusive 70% discount, making it an accessible solution for individuals committed to improving their mental and emotional well-being. Lumo Therapy is engineered for individuals looking to harness the natural power of light to combat fatigue, stress, and seasonal blues . Its sleek, portable design ensures users can enjoy its benefits at home, in the office, or on the go. With customizable settings and therapeutic-grade light wavelengths, this device is at the forefront of health innovation. Light therapy has been a trusted method in addressing mood disorders and energy imbalances for decades. Studies show that exposure to specific wavelengths of light can positively affect the body's circadian rhythm, boost serotonin levels, and decrease melatonin production. Lumo Therapy amplifies these benefits by using state-of-the-art LED technology to deliver consistent, targeted light exposure, helping users feel rejuvenated and balanced throughout their day. Seasonal depression and energy dips affect millions globally, especially during the colder months. Reduced sunlight during fall and winter can disrupt the body's internal clock, leading to fatigue, mood swings, and diminished productivity. Lumo Therapy offers a natural, effective solution to these challenges, providing users with the boost they need to maintain a positive outlook and energy year-round. This exclusive 70% discount comes at a critical time, ensuring the benefits of Lumo Therapy are accessible to everyone . Whether it's for professional demands, personal obligations, or general health improvement, the device equips individuals to perform their best no matter the season. Benefits of Lumo Therapy Early users of Lumo Therapy have shared overwhelmingly positive feedback.“Lumo Therapy has truly been a game-changer for me,” says Nina Williams, a verified user.“After just a few sessions, I felt more energetic and focused. I can't imagine starting my day without it!” The exclusive 70% discount can be redeemed through Lumo Therapy's official website. To claim this offer and transform your well-being today. Supplies are limited, so don't miss this opportunity to experience the benefits of light therapy at a fraction of the cost. Lumo Therapy is a leading innovator in wellness technology, committed to creating products that enhance quality of life through science-backed solutions . With a focus on accessibility, effectiveness, and user experience, Lumo Therapy is transforming the landscape of personal health and well-being. MENAFN19122024003238003268ID1109014478 Legal Disclaimer: MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above.Agnico-Eagle Mines Ltd. stock falls Tuesday, still outperforms market
Surveillance tech advances by Biden could aid in Trump's promised crackdown on immigration(BPT) - This article was sponsored and developed by Neurocrine Biosciences, Inc. Cerebral palsy (CP) is a neurodevelopmental disorder affecting movement and posture that begins in early childhood development. It is the most common cause of motor disability in children, affecting about one in 345 children in the United States. 1-2 It may happen as a result of lack of oxygen during or around birth, stroke, infection, a problem with metabolism or other problems that cause injury or affect the development of parts of the brain involved in movement control in the first few years of life. 3 CP is a permanent condition, affecting a person for their entire life. People living with CP typically have motor problems, which may include spasticity (abnormal muscle tightness), dyskinesia (uncontrolled movements) or ataxia (poor muscle control), and many people have a mix of these motor disorders. 4 Dyskinesia due to CP (DCP) is one of the most disabling forms of CP and impacts approximately 10% to 20% of people living with CP. 5-6 According to the Cerebral Palsy Foundation (CPF), the combination of irregular and unpredictable movements (chorea) and twisting and repeating movements (dystonia) often disrupt activities and cause significant functional impairment, including the ability to maintain balance, walk or fine motor control. 7 Heather Riordan, M.D., Neurologist and Movement Disorders Specialist, Director of the Phelps Center for Cerebral Palsy at the Kennedy Krieger Institute, discusses the symptoms of chorea and impact on patients in a video shared on the CPF website here . About 30% of people with DCP are affected mostly by these involuntary and irregular movements (chorea), while dystonia is the predominant motor finding in the remaining 70%. 8 However, it is common for both chorea and dystonia movements to be present together. 6 For people living with DCP, these movements can occur in any region of the body, including the arms and legs, torso and face and may vary in severity. They are often triggered or made worse by stimulation or stress. Because dyskinesia can occur at rest and/or when actively using the body, the problems with movement are very burdensome in day-to-day living, with discomfort and pain affecting the quality of life for people and their caregivers. 9 Jen Lyman, mom to a son with DCP, highlights how dyskinesia makes communicating more difficult. "The most difficult thing about dyskinesia is watching my son struggle to do things that he wants to do, but the extra movements get in the way...special things, such as using a touch screen to video chat with his grandmother, are nearly impossible despite his best efforts to use his hands and fingers. Something so simple, yet so special for him should be effortless." DCP has a wide-ranging impact on the individual, including lifelong challenges with movement, a higher risk of other medical issues, a higher rate of mental health challenges and difficulties with communication. 10-12 "Those of us who have the privilege to serve patients with dyskinetic, hyperkinetic or mixed cerebral palsy see the functional impact of this very challenging type of tone every day," said Susan Biffl, M.D., Rehabilitation Medicine Specialist at Rady Children's Hospital-San Diego and Assistant Professor at UC San Diego School of Medicine. "Patients face challenges with self-care, independence, mobility, communication, fine motor skills that affect occupational and recreational activities, swallowing, social interactions and even sleep. As this tone is variable, it is much more challenging to treat than more consistent tone issues, such as spasticity." Treatment Options There are currently no Food and Drug Administration-approved treatments for DCP. Dystonia and chorea are often managed separately as they respond differently to various treatments, which can make treatment challenging. 3 Most drugs being investigated for DCP have focused on dystonia, and more research is needed to determine potential treatments for chorea. New treatment options are needed to help manage these movement disorders and improve daily function and quality of life for those affected. "After 20 years of caring for individuals with cerebral palsy, I continue to find those with dyskinetic cerebral palsy among the most challenging to treat, largely due to the limited effectiveness of available pharmacologic options," said Joyce Oleszek, M.D., Professor, Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine. "There is an urgent need for more robust evidence to support pharmacologic treatments for this condition, given its profound impact on function, comfort and quality of life." Ongoing Research Clinical studies are important in the development of treatment options, allowing researchers to evaluate the safety and effectiveness of new medicines. The data from clinical studies are used to determine if an investigational treatment can be approved for use to treat certain disorders. There are ongoing clinical studies evaluating potential treatments for DCP, including one for chorea. Neurocrine Biosciences is conducting the KINECT ® -DCP clinical study, a Phase 3, randomized, double-blind placebo-controlled study investigating the study drug, valbenazine, for the treatment of DCP. The clinical study is currently enrolling children, adolescents and adults six to 70 years of age who have been diagnosed with DCP. "The Cerebral Palsy Foundation is excited to partner with Neurocrine Biosciences on this study," said Rachel Byrne, Executive Director of the Cerebral Palsy Foundation. "We are proud to support strong research that can potentially bring meaningful change to the lives of those living with cerebral palsy." If you or someone you know may be eligible for this research study, please visit the study website for additional information here: FindADCPStudy.com . REFERENCES © 2024 Neurocrine Biosciences, Inc. All Rights Reserved. CAP-NBI-US-0115 12/2024 NBI-98854-DCP3018_11DecMatRelease_v1.0_25November2024LG’s mosquito-repelling AC hits Nigerian market
Headline: Beijing Exposed Soft Center in Loss! Center fouls out, scores 13 points off the bench, got completely outplayed by Liu Chuanxing, Zhou Qi's struggles take center stage
Dyskinetic Cerebral Palsy: A Closer Look at Symptoms, Diagnosis and Clinical Research Underway
The increase in China's gold reserves comes as part of a broader strategy to boost the country's foreign exchange reserves. China's foreign exchange reserves have been climbing steadily in recent months, reaching a record high of XXXX billion dollars in the first quarter of XXXX. The rise in reserves is seen as a positive sign for the Chinese economy, as it provides a cushion against external shocks and helps maintain stability in the financial markets.
