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Report: UCF HC Gus Malzahn to become Florida State OCAROC-3 is under clinical development by and currently in Phase II for IgA Nephropathy (Berger’s Disease). According to GlobalData, Phase II drugs for IgA Nephropathy (Berger’s Disease) have a 50% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. AROC-3 overview AROC-3 is under development for the treatment of adult patients with complement-mediated renal disease (C3 glomerulopathy [C3G] (glomerulonephritis) and IgA nephropathy [IgAN]). It acts by targeting complement component 3. The drug candidate is a siRNA developed which is based on Targeted RNAi Molecule (TRiM) platform. It is administered through subcutaneous route. It was also under development for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Arrowhead Pharmaceuticals overview (Arrowhead) is a biotech company that develops and commercializes gene silencing therapeutics. The company utilizes RNA chemistries and TRiM platform to target and silence disease-causing genes. Its pipeline products include ARO-APOC3, ARO-ANG3, Olpasiran, GSK-4532990, ARO-PNPLA3, ARO-RAGE, ARO-MMP7, ARO-MUC5AC, Fazirsiran, ARO-HB, ARO-DUX4 and ARO-DM1. Arrowhead product indications include hypertriglyceridemia, dyslipidemia, cardiovascular disease, nonalcoholic steatohepatitis, inflammatory, idiopathic pulmonary fibrosis, idiopathic pulmonary fibrosis, much-obstructive, alpha-1 liver disease, hepatitis b, facioscapulohumeral muscular dystrophy and myotonic dystrophy type 1. The company operates lab facilities in San Diego, California and Madison, Wisconsin, the US. Arrowhead is headquartered in Pasadena, California, the US. For a complete picture of AROC-3’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .Hydrocodone IR is under clinical development by Elysium Therapeutics and currently in Phase I for Opium (Opioid) Addiction. According to GlobalData, Phase I drugs for Opium (Opioid) Addiction have a 71% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Hydrocodone IR overview Hydrocodone immediate release is under development for the treatment of pain due to prescription opioid use disorder and opium (Opioid) addiction. It acts by targeting mu-type opioid receptor. The drug candidate is developed based on O2P (oral overdose protection) technology. It is an immediate release formulation. It is administered through oral route. Elysium Therapeutics overview Elysium Therapeutics is developing safer opioids for the treatment of opioid use disorder. The company is headquartered in Lyons, Colorado, the US. For a complete picture of Hydrocodone IR’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .888 jili slot 。

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NEW YORK (AP) — Richard Parsons, one of corporate America's most prominent Black executives who held top posts at Time Warner and Citigroup, died Thursday. He was 76. Parsons, who died at his Manhattan home, was diagnosed with multiple myeloma in 2015 and cited “unanticipated complications” from the disease for cutting back on work a few years later. The financial services company Lazard, where Parsons was a longtime board member, confirmed his death. The NBA, where Parsons was interim CEO of the Los Angeles Clippers in 2014, was among organizations offering condolences. “Dick Parsons was a brilliant and transformational leader and a giant of the media industry who led with integrity and never shied away from a challenge,” NBA Commissioner Adam Silver said. Parsons’ friend Ronald Lauder told The New York Times that the cause of death was cancer. Parsons stepped down Dec. 3 from the boards of Lazard and Lauder's company, Estée Lauder, citing health reasons. He had been on Estée Lauder’s board for 25 years. Parsons, a Brooklyn native who started college at 16, was named chairman of Citigroup in 2009, one month after leaving Time Warner Inc., where he helped restore the company’s stature following its much-maligned acquisition by internet provider America Online Inc. He steered Citigroup back to profit after financial turmoil from the subprime mortgage crisis, which upended the economy in 2007 and 2008. Parsons was named to the board of CBS in September 2018 but resigned a month later because of illness. Parsons said in a statement at the time that he was already dealing with multiple myeloma when he joined the board, but “unanticipated complications have created additional new challenges.” He said his doctors advised him to cut back on his commitments to ensure recovery. “Dick’s storied career embodied the finest traditions of American business leadership,” Lazard said in a statement. The company, where Parsons was a board member from 2012 until this month, praised his “unmistakable intelligence and his irresistible warmth.” “Dick was more than an iconic leader in Lazard’s history — he was a testament to how wisdom, warmth, and unwavering judgment could shape not just companies, but people’s lives,” the company said. “His legacy lives on in the countless leaders he counseled, the institutions he renewed, and the doors he opened for others.” Parsons was known as a skilled negotiator, a diplomat and a crisis manager. Although he was with Time Warner through its difficulties with AOL, he earned respect for the company and rebuilt its relations with Wall Street. He streamlined Time Warner’s structure, pared debt and sold Warner Music Group and a book publishing division. He also fended off a challenge from activist investor Carl Icahn in 2006 to break up the company and helped Time Warner reach settlements with investors and regulators over questionable accounting practices at AOL. Parsons joined Time Warner as president in 1995 after serving as chairman and chief executive of Dime Bancorp Inc., one of the largest U.S. thrift institutions. In 2001, after AOL used its fortunes as the leading provider of Internet access in the U.S. to buy Time Warner for $106 billion in stock, Parsons became co-chief operating officer with AOL executive Robert Pittman. In that role, he was in charge of the company’s content businesses, including movie studios and recorded music. He became CEO in 2002 with the retirement of Gerald Levin, one of the key architects of that merger. Parsons was named Time Warner chairman the following year, replacing AOL founder Steve Case, who had also championed the combination. The newly formed company’s Internet division quickly became a drag on Time Warner. The promised synergies between traditional and new media never materialized. AOL began seeing a reduction in subscribers in 2002 as Americans replaced dial-up connections with broadband from cable TV and phone companies. Parsons stepped down as CEO in 2007 and as chairman in 2008. A year later AOL split from Time Warner and began trading as a separate company, following years of struggles to reinvent itself as a business focused on advertising and content. Time Warner is now owned by AT&T Inc. A board member of Citigroup and its predecessor, Citibank, since 1996, Parsons was named chairman in 2009 at a time of turmoil for the financial institution. Citigroup had suffered five straight quarters of losses and received $45 billion in government aid. Its board had been criticized for allowing the bank to invest so heavily in the risky housing market. Citigroup returned to profit under Parsons, starting in 2010, and would not have a quarterly loss again until the fourth quarter of 2017. Parsons retired from that job in 2012. In 2014 he stepped in as interim CEO of the Clippers until Microsoft CEO Steve Ballmer took over later that year. Parsons, a Republican, previously worked as a lawyer for Nelson Rockefeller, a former Republican governor of New York, and in Gerald Ford’s White House. Those early stints gave him grounding in politics and negotiations. He also was an economic adviser on President Barack Obama’s transition team. Parsons, who loved jazz and co-owned a Harlem jazz club, also served as Chairman of the Apollo Theater and the Jazz Foundation of America. And he held positions on the boards of the Smithsonian National Museum of African American History and Culture, the American Museum of Natural History and the Museum of Modern Art in New York City. Parsons played basketball at the University of Hawaii at Manoa and received his law degree from Albany Law School in 1971. He is survived by his wife, Laura, and their family. This obituary was primarily written by the late Associated Press reporter Anick Jesdanun, who died in 2020 .Scintillator Market Size, Share & Trends Analysis Report Forecast Period (2024-2031). 12-25-2024 07:29 PM CET | Business, Economy, Finances, Banking & Insurance Press release from: Orion Market Research Scintillators market is anticipated to grow at a CAGR of 4.7% during the forecast period (2024-2031). Scintillators are substances that emit light while contacting ionizing radiation, including gamma rays, X-rays, and high-energy particles. This property, called scintillation, finds widespread application across industries for the detection and measurement of radiation in diverse applications. The market growth is driven by rising demand for radiation detectors, advancements in scintillator materials and manufacturing techniques, stringent regulations mandating radiation monitoring and safety measures, and the expanding application of scintillators in fields such as environmental monitoring and space exploration. Get Sample Copy of this Report at https://www.omrglobal.com/request-sample/scintillator-market Organic Scintillators the Preferred Material Composition Organic scintillators are increasingly preferred owing to their versatility and efficiency in detecting ionizing radiation. Its ability to offer high sensitivity to fast neutrons and low-energy gamma rays makes organic scintillators ideal for diverse applications in medical imaging, environmental monitoring, and nuclear research. Further, segmental growth is expected to be driven by sustainability trends across sectors, technological advancements in organic scintillator devices, and innovation in organic scintillator materials, expanding their role in emerging fields like space exploration and high-energy physics. Healthcare Holds Major Share Based on End-User Segment Healthcare applications are poised to dominate the scintillator market owing to increasing demand for advanced medical imaging technologies such as PET and SPECT scanners, which rely heavily on scintillator detectors, rising incidences of chronic diseases requiring accurate diagnostic tools, and ongoing technological advancements improving sensitivity and resolution. Further, the market is expected to be influenced by the growing integration of scintillator-based systems in hybrid imaging modalities and expanding applications in personalized medicine, resulting in the growth of the healthcare segment. Regional Outlook The global scintillator market is further segmented based on geography including North America (the US, and Canada), Europe (the UK, Italy, Spain, Germany, France, and the Rest of Europe), Asia-Pacific (India, China, Japan, South Korea, and Rest of Asia-Pacific), and the Rest of the World (the Middle East & Africa, and Latin America). North America is Estimated to Dominate the Global Scintillators Market North America is projected to deliver the highest growth rate in the future, attributed to the increasing investment in the development of novel scintillator materials and devices, strong demand for advanced healthcare infrastructure in the region, a higher level of defense and homeland security spending, stringent regulation regarding radiation monitoring and safety measures, and the expansion of scintillator applications in space programs. For instance, in May 2024, NASA launched the initial climate satellite of a pair to analyze heat emissions at the Earth's poles, which has successfully entered orbit following its launch on Rocket Lab's Electron rocket from Launch Complex 1 in M?hia, New Zealand. The PREFIRE (Polar Radiant Energy in the Far-Infrared Experiment) mission by the agency comprises two CubeSats, each the size of a shoebox, which will assess the heat emitted by Earth into space from two of the most frigid and isolated regions on the planet. The data gathered from the PREFIRE mission will enhance researchers' ability to forecast changes in Earth's ice, oceans, and climate in a warming environment. Global Scintillator Market Growth by Region 2024-2031 The regional healthcare sector has a substantial demand for imaging devices and related services owing to the rise in chronic disease and growing awareness of early diagnosis, which is expected to benefit the market. Asia-Pacific countries are increasingly investing in new nuclear power projects to meet growing energy demands, creating opportunities for scintillator detectors in radiation monitoring and safety systems. by Material Composition (Scintillators, and Inorganic Scintillators), and by Application (Healthcare, Nuclear Power Plants, Homeland Security and Defense, and Others) Market Players Outlook The major companies serving the global scintillator market include Hamamatsu Photonics K.K., Hitachi Metals Group, and NuviaTech Instruments (Soletanche Freyssinet) among others. The market players are focusing on capitalizing on growth by adopting strategies such as collaboration, partnerships, and market expansion among others. For instance, in April 2024, Inrad Optics, Inc. a manufacturer of advanced optical Material Compositions, assemblies, and systems, announced that it would be acquired by Luxium Solutions an affiliate of private equity firms SK Capital Partners ("SK Capital") and Edgewater Capital Partners, through a definitive merger agreement. The all-cash transaction values Inrad Optics at approximately $19.0 million, inclusive of assumed debt. full report Scintillator Market of available https://www.omrglobal.com/industry-reports/scintillator-market The Report Covers Market value data analysis of 2023 and forecast to 2031. Annualized market revenues ($ million) for each market segment. Country-wise analysis of major geographical regions. Key companies operating in the global scintillator market. Based on the availability of data, information related to new product launches, and relevant news is also available in the report. Analysis of business strategies by identifying the key market segments positioned for strong growth in the future. Analysis of market-entry and market expansion strategies. Competitive strategies by identifying 'who-stands-where' in the market. For More Customized Data, Request for Report Customization https://www.omrglobal.com/report-customization/scintillator-market Media Contact: Company Name: Orion Market Research Contact Person: Mr. Anurag Tiwari Email: info@omrglobal.com Contact no: +91 780-304-0404 About Orion Market Research Orion Market Research (OMR) is a market research and consulting company known for its crisp and concise reports. The company is equipped with an experienced team of analysts and consultants. OMR offers quality syndicated research reports, customized research reports, consulting and other research-based services. The company also offers Digital Marketing services through its subsidiary OMR Digital and Software development and Consulting Services through another subsidiary Encanto Technologies. This release was published on openPR.

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Kyle Shanahan reveals plan for Javon Hargrave after 49ers' decision to restructure his contractMassachusetts Wealth Management grew its holdings in Amazon.com, Inc. ( NASDAQ:AMZN – Free Report ) by 100.6% in the third quarter, according to the company in its most recent 13F filing with the SEC. The institutional investor owned 7,978 shares of the e-commerce giant’s stock after buying an additional 4,001 shares during the quarter. Massachusetts Wealth Management’s holdings in Amazon.com were worth $1,487,000 as of its most recent filing with the SEC. Other hedge funds also recently made changes to their positions in the company. International Assets Investment Management LLC grew its holdings in shares of Amazon.com by 20,897.2% in the 3rd quarter. International Assets Investment Management LLC now owns 39,135,449 shares of the e-commerce giant’s stock worth $72,921,080,000 after purchasing an additional 38,949,065 shares during the last quarter. Vanguard Group Inc. grew its holdings in shares of Amazon.com by 1.9% in the 1st quarter. Vanguard Group Inc. now owns 785,811,114 shares of the e-commerce giant’s stock worth $141,744,609,000 after purchasing an additional 14,724,687 shares during the last quarter. Swedbank AB bought a new stake in shares of Amazon.com in the 1st quarter worth about $2,239,757,000. Capital World Investors grew its holdings in shares of Amazon.com by 64.6% in the 1st quarter. Capital World Investors now owns 29,359,677 shares of the e-commerce giant’s stock worth $5,295,899,000 after purchasing an additional 11,524,463 shares during the last quarter. Finally, Capital Research Global Investors grew its holdings in shares of Amazon.com by 8.5% in the 1st quarter. Capital Research Global Investors now owns 86,982,857 shares of the e-commerce giant’s stock worth $15,689,968,000 after purchasing an additional 6,810,145 shares during the last quarter. Institutional investors and hedge funds own 72.20% of the company’s stock. Wall Street Analysts Forecast Growth AMZN has been the topic of several analyst reports. Redburn Atlantic upped their target price on shares of Amazon.com from $225.00 to $235.00 and gave the stock a “buy” rating in a report on Tuesday. Morgan Stanley increased their price objective on shares of Amazon.com from $210.00 to $230.00 and gave the stock an “overweight” rating in a report on Monday, November 4th. Telsey Advisory Group increased their price objective on shares of Amazon.com from $215.00 to $235.00 and gave the stock an “outperform” rating in a report on Friday, November 1st. Jefferies Financial Group increased their price objective on shares of Amazon.com from $225.00 to $235.00 and gave the stock a “buy” rating in a report on Friday, November 1st. Finally, Robert W. Baird increased their price objective on shares of Amazon.com from $213.00 to $220.00 and gave the stock an “outperform” rating in a report on Friday, November 1st. Two research analysts have rated the stock with a hold rating, forty-one have given a buy rating and one has issued a strong buy rating to the stock. Based on data from MarketBeat.com, Amazon.com has a consensus rating of “Moderate Buy” and an average price target of $236.20. Insider Activity at Amazon.com In other Amazon.com news, insider Jeffrey P. Bezos sold 2,996,362 shares of Amazon.com stock in a transaction on Friday, November 8th. The shares were sold at an average price of $208.85, for a total value of $625,790,203.70. Following the sale, the insider now directly owns 917,416,976 shares in the company, valued at approximately $191,602,535,437.60. The trade was a 0.33 % decrease in their position. The sale was disclosed in a filing with the Securities & Exchange Commission, which is accessible through this link . Also, SVP David Zapolsky sold 2,190 shares of Amazon.com stock in a transaction on Tuesday, September 24th. The shares were sold at an average price of $195.00, for a total transaction of $427,050.00. Following the completion of the sale, the senior vice president now owns 62,420 shares in the company, valued at $12,171,900. The trade was a 3.39 % decrease in their ownership of the stock. The disclosure for this sale can be found here . In the last ninety days, insiders have sold 6,026,683 shares of company stock valued at $1,252,148,795. 10.80% of the stock is owned by corporate insiders. Amazon.com Trading Up 1.0 % AMZN opened at $207.89 on Friday. The stock has a market capitalization of $2.19 trillion, a P/E ratio of 44.52, a P/E/G ratio of 1.38 and a beta of 1.14. Amazon.com, Inc. has a 12 month low of $142.81 and a 12 month high of $215.90. The firm’s fifty day simple moving average is $194.78 and its 200 day simple moving average is $186.94. The company has a current ratio of 1.09, a quick ratio of 0.87 and a debt-to-equity ratio of 0.21. Amazon.com ( NASDAQ:AMZN – Get Free Report ) last posted its quarterly earnings data on Thursday, October 31st. The e-commerce giant reported $1.43 EPS for the quarter, beating the consensus estimate of $1.14 by $0.29. The business had revenue of $158.88 billion for the quarter, compared to analysts’ expectations of $157.28 billion. Amazon.com had a net margin of 8.04% and a return on equity of 22.41%. The firm’s revenue was up 11.0% compared to the same quarter last year. During the same period in the previous year, the firm posted $0.85 EPS. As a group, research analysts anticipate that Amazon.com, Inc. will post 5.29 EPS for the current fiscal year. Amazon.com Company Profile ( Free Report ) Amazon.com, Inc engages in the retail sale of consumer products, advertising, and subscriptions service through online and physical stores in North America and internationally. The company operates through three segments: North America, International, and Amazon Web Services (AWS). It also manufactures and sells electronic devices, including Kindle, Fire tablets, Fire TVs, Echo, Ring, Blink, and eero; and develops and produces media content. Featured Stories Five stocks we like better than Amazon.com Stock Average Calculator The Latest 13F Filings Are In: See Where Big Money Is Flowing How to Find Undervalued Stocks 3 Penny Stocks Ready to Break Out in 2025 High Flyers: 3 Natural Gas Stocks for March 2022 FMC, Mosaic, Nutrien: Top Agricultural Stocks With Big Potential Receive News & Ratings for Amazon.com Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Amazon.com and related companies with MarketBeat.com's FREE daily email newsletter .

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