Trudeau told Trump Americans would also suffer if tariffs are imposed, a Canadian minister saysNone

Star Group, L.P. Reports Fiscal 2024 Fourth Quarter Results

Games on a college basketball schedule don't contrast much more than the two NC State has this week. The Wolfpack (6-3) host Coppin State (0-10) on Tuesday in Raleigh, N.C., then hit the road to challenge No. 10 Kansas on Saturday. NC State enters its unusual week after snapping a three-game skid with an 84-74 overtime win at home Saturday against Florida State in its Atlantic Coast Conference opener. Transfers Marcus Hill and Dontrez Styles each had their season high, scoring 23 and 21 points, respectively. They scored 13 of NC State's 14 points in overtime. "Dontrez Styles was tremendous," Wolfpack coach Kevin Keatts said. "In the second half, he made play after play." Hill, who was the top scorer last year at Bowling Green (20.5 points per game), and Styles, who was the second-leading scorer last year at Georgetown (12.8 ppg), combined to hit 14 of 25 shots and pull down 11 rebounds. The win followed defeats to then-No. 13 Purdue and BYU, both by double-digit margins, in the Rady Children's Invitational and a 63-59 loss to Texas in the SEC/ACC Challenge. "The little things that impact the game are defending, making free throws and blocking out," Keatts said. "We handled that much better than we did against Texas." Coppin State arrives in Raleigh on a 23-game losing streak dating to January -- the longest current run of futility in Division I. Each of the Eagles' losses this season have come by double-digit margins, though they have been more competitive lately, falling to Baltimore rival Loyola (Md.) 68-57 and at Wagner 65-52 last week. Julius Ellerbe III has been one of Coppin's most reliable players lately, scoring a combined 20 points in the last two games. He had 16 points and 12 rebounds in a loss to George Mason last month. Teammate Peter Oduro recorded a double-double, with 16 points and 10 rebounds, in last month's loss at Saint Joseph's. "These things take time," Coppin State second-year coach Larry Stewart said. "It takes time to establish your culture. It takes time to get the right players in your system." --Field Level MediaBuccaneers are back to .500 and in position to control their playoff hopes down the stretch

NoneSANTA CLARA, Calif., Dec. 09, 2024 (GLOBE NEWSWIRE) -- AMD (NASDAQ: AMD) today announced that Tim Keating has joined the company as senior vice president, Government Relations and Regulatory Affairs, effective today. “Tim is a strong addition to lead our government relations team,” said Ava Hahn, AMD senior vice president, general counsel and corporate secretary. “As high-performance and AI chips play an increasingly larger role in our daily lives over the coming years, Tim’s extensive public policy expertise and deep understanding of regulatory landscapes will play a critical role expanding our engagements with key stakeholders.” Keating has decades of experience, including more than 14 years at Boeing as executive vice president, Government Relations. Before Boeing, he was the senior vice president of Global Government Operations at Honeywell International and served as special assistant to the President of the United States and as staff director for White House Legislative Affairs. He also held several positions with the U.S. House of Representatives. Keating received a bachelor’s degree in political science from the University of Scranton and an honorary doctorate of business administration from the University of South Carolina. About AMD For more than 50 years AMD has driven innovation in high-performance computing, graphics and visualization technologies. Billions of people, leading Fortune 500 businesses and cutting-edge scientific research institutions around the world rely on AMD technology daily to improve how they live, work and play. AMD employees are focused on building leadership high-performance and adaptive products that push the boundaries of what is possible. For more information about how AMD is enabling today and inspiring tomorrow, visit the AMD (NASDAQ: AMD) website , blog , LinkedIn and X pages. AMD, the AMD Arrow logo and combinations thereof, are trademarks of Advanced Micro Devices, Inc. Contact: Brandi Martina AMD Communications (512) 705-1720 Brandi.martina@amd.com Mitch Haws AMD Investor Relations 512-944-0790 mitch.haws@amd.comCyber Monday Samsung deals: Save up to $2,500 on TVs, phones, and moreCeltics vs. Pacers Injury Report Today – December 27

Philippe Clement pointed to selection struggles as he responded to a question on the attacking nature of his side against Kilmarnock. Rangers ran rampant against the Ayrshire side with a flurry of goals in the second half to earn a 6-0 victory in the Scottish Premiership. Danilo started up front with Hamza Igamane also involved from the start alongside Ianis Hagi and Vaclav Cerny. Clement discussed his team selection post-match as he insisted the only reason it has taken time to adopt a more attacking system is down to player availability. Responding to a question on the starting XI "setting the tone and Rangers on the front foot", Clement said: "Yes, but how many times in this one year did I have two strikers available in the squad? That's the reality of the story also. Read more: Clement confirms Rangers 'big discussions' over transfer window "So it's major, it's important to keep everybody fit and you say now the right choices, but I'm sure if we didn't win with 6-0 that maybe you would have said, why is Connor Barron not starting today? "It's like that. It's like that, but all these players are pushing, they're working hard. I cannot say anything about that. "We need to keep it that way and then they all will have their moments to shine. They all will have their moments also to sit on the bench and to be ready for the next game because it's such an ultra marathon this season that we need this rotation and smart rotation in the squad and that's what we're going to do the next weeks and the next month. "So I'm sure maybe you're going to be the first one if we don't win the game to say, why is that one not playing? But that's easy after the game with insight. So that's the difficulty about this job."

Trudeau told Trump Americans would also suffer if tariffs are imposed, a Canadian minister says

Berlin confirmed plans to reform its legal framework make it a clear criminal offence to “facilitate the smuggling of migrants to the UK” as part of the agreement, the Home Office said. The Home Office said the move would give German prosecutors more tools to tackle the supply and storage of dangerous small boats. Both countries will also commit to exchange information that may help to remove migrant-smuggling content from social media platforms and tackle end-to-end routes of criminal smuggling networks as part of the deal. It comes ahead of the UK and Germany hosting the so-called Calais Group in London, which sees ministers and police from the two countries, alongside France, Belgium and the Netherlands, gather to discuss migration in Europe. Delegates are expected to agree a detailed plan to tackle people-smuggling gangs in 2025 at the meeting on Tuesday. Home Secretary Yvette Cooper said: “For too long organised criminal gangs have been exploiting vulnerable people, undermining border security in the UK and across Europe while putting thousands of lives at risk. “We are clear that this cannot go on. “Germany is already a key partner in our efforts to crack down on migrant smuggling, but there is always more we can do together. “Our new joint action plan with deliver a strengthened partnership with Germany, boosting our respective border security as we work to fix the foundations, and ultimately saving lives.” Nancy Faeser, German federal minister of the interior said: “We are now stepping up our joint action to fight the brutal activities of international smugglers. “This is at the core of our joint action plan that we have agreed in London. “I am very grateful to my British counterpart Yvette Cooper that we were able to reach this important agreement. “It will help us end the inhumane activities of criminal migrant smuggling organisations. “By cramming people into inflatable boats under threats of violence and sending them across the Channel, these organisations put human lives at risk. “Many of these crimes are planned in Germany. “Together, we are now countering this unscrupulous business with even more resolve. “This includes maintaining a high investigative pressure, exchanging information between our security authorities as best as possible, and persistently investigating financial flows to identify the criminals operating behind the scenes.”

Share Tweet Share Share Email In the fast-paced world of digital innovation, blockchain and cryptocurrency platforms continue to break boundaries, offering transformative solutions to global challenges. Among these cutting-edge projects are Qubetics , Solana, Hedera, Cardano, and Litecoin, each contributing uniquely to the evolution of decentralized ecosystems. Let’s explore these platforms, their offerings, and their potential to redefine financial landscapes. 1. Qubetics: Revolutionizing Cross-Border Payments In today’s interconnected global economy, the need for efficient and secure cross-border payments is more urgent than ever. The Qubetics Network rises to this challenge by providing a state-of-the-art platform designed to streamline international transactions for businesses and individuals alike. For businesses, Qubetics simplifies settlement processes, ensuring optimal cash flow and operational efficiency. By enabling quick transfers and settlements, companies can respond swiftly to market demands, enhance their competitive edge, and drive sustainable growth. The platform offers a hassle-free remittance solution for individuals, eliminating the delays and complications often associated with traditional payment methods. Qubetics is currently in Presale Phase 14, with $TICS tokens priced at $0.037. The presale phase has raised over $7.7 million, attracted more than 11,700 holders, and sold 374 million tokens. Weekly price hikes of 10% culminate in a final phase surge of 20%, making this a prime opportunity for investors. Post-presale, the token is expected to launch at $0.25, representing a potential ROI of 563.81% for early adopters. Analysts predict explosive growth following the mainnet launch, with prices potentially reaching $10 to $15 per token. A $10 valuation would equate to an ROI of 26,452.57%, while a $15 valuation could see returns soar to 39,728.85%. Qubetics is poised to disrupt global finance, making cross-border payments faster, more affordable, and accessible for all. 2. Solana: A High-Performance Blockchain Platform Solana is renowned for its high-speed transactions and scalability, positioning itself as a leading blockchain for decentralised applications (dApps) and cryptocurrency projects. The platform’s architecture is built to handle thousands of transactions per second, far outpacing most of its competitors. By leveraging Proof of History (PoH) alongside Proof of Stake (PoS), Solana ensures unparalleled efficiency and security. Developers flock to the platform for its low fees and lightning-fast performance, making it an ideal ecosystem for DeFi projects, NFT marketplaces, and gaming applications. Solana’s community-driven approach fosters innovation, empowering developers to build on a robust and scalable network. Its ecosystem continues to grow, making it a key player in the blockchain space. 3. Hedera: The Leader in Enterprise-Grade Blockchain Solutions Hedera Hashgraph stands out with its unique consensus algorithm, offering a more energy-efficient and secure alternative to traditional blockchains. Hedera is designed for enterprise applications and ensures rapid transaction speeds, low costs, and high reliability. The platform’s Hashgraph consensus mechanism enables unparalleled scalability, supporting up to 10,000 transactions per second. Hedera’s governance model, comprising industry leaders like Google and IBM, adds to its credibility and adoption. Hedera’s diverse use cases range from supply chain optimisation and healthcare data management to tokenisation and payments. Its focus on enterprise-grade solutions makes it a vital tool for businesses seeking blockchain integration. 4. Cardano: A Visionary Approach to Blockchain Technology Cardano is a research-driven blockchain that prioritises security, scalability, and sustainability. Built on a layered architecture, it separates computation from settlement, allowing enhanced functionality without compromising efficiency. Cardano’s Ouroboros Proof of Stake (PoS) protocol is a pioneering consensus mechanism that reduces energy consumption while maintaining network integrity. Its rigorous peer-reviewed development process ensures reliability and innovation. The platform’s commitment to social impact is evident in its digital identity and financial inclusion projects. Cardano aims to provide blockchain solutions to underserved communities, empowering individuals and organisations. Cardano continues to attract developers, businesses, and investors as its ecosystem expands, cementing its position as a leader in blockchain innovation. 5. Litecoin: The Silver Standard of Cryptocurrency Litecoin, one of the earliest cryptocurrencies, remains steadfast in the blockchain landscape. Litecoin offers a lightweight alternative to Bitcoin, known for its simplicity and speed, with faster transaction times and lower fees. The platform’s Scrypt algorithm ensures a more decentralised mining process, making it accessible to a broader audience. Litecoin’s focus on usability has made it a popular choice for day-to-day transactions and as a testing ground for Bitcoin innovations. Litecoin’s longevity and adaptability continue to make it a reliable option for investors and users, solidifying its role in the cryptocurrency ecosystem. Conclusion Qubetics, Solana, Hedera, Cardano, and Litecoin collectively drive the blockchain revolution. Each platform addresses distinct challenges, from cross-border payments and high-speed transactions to enterprise solutions, research-driven development, and everyday usability. These projects are not just technological marvels but pivotal elements in the broader financial and technological progress narrative. As they continue to grow and evolve, they open doors to new opportunities, empowering individuals and businesses to thrive in an increasingly digital world. Investors, developers, and enthusiasts stand to benefit from the transformative potential of these platforms. By embracing the innovations they offer, we can shape a future defined by efficiency, accessibility, and global connectivity. For More Information: Qubetics: https://qubetics.com Telegram: https://t.me/qubetics Twitter: https://x.com/qubetics Related Items: Blockchain , Qubetic Share Tweet Share Share Email Recommended for you BTFD Coin’s Discount Offer And The Top 5 Picks for The Best Cryptos to Join for Short Term Gains Top Cryptocurrencies to Watch in 2024 | Top 3 Potential Breakout Stars Innerworks and Bittensor ($TAO) Collaborate to Unveil RedTeam Platform to Enhance Cybersecurity Innovation Comments

NoneWASHINGTON (AP) — American Airlines briefly grounded flights nationwide Tuesday because of a technical problem just as the Christmas travel season kicked into overdrive and winter weather threatened more potential problems for those planning to fly or drive. Government regulators cleared American flights to get airborne about an hour after the Federal Aviation Administration ordered a national ground stop for the airline. The order, which prevented planes from taking off, was issued at the airline's request after it experienced trouble with its flight operating system, or FOS. The airline blamed technology from one of its vendors. As a result, flights were delayed across American’s major hubs, with only 37% of the airline's 3,901 domestic and international flights leaving on time, according to Cirium, an aviation analytics company. Nineteen flights were canceled. Dennis Tajer, a spokesperson for the Allied Pilots Association, a union representing American Airlines pilots, said the airline told pilots at 7 a.m. Eastern that there was an outage affecting the FOS system. It handles different types of airline operations, including dispatch, flight planning, passenger boarding, as well as an airplane's weight and balance data, he said. Some components of FOS have gone down in the past, but a systemwide outage is rare, Tajer said. Hours after the ground stop was lifted, Tajer said the union had not heard about any “chaos out there beyond just the normal heavy travel day.” He said officials were watching for any cascading effects, such as staffing problems. On social media, however, customers expressed frustrations about delays that caused them or their family members to miss connecting flights. One person asked if American planned to hold flights for passengers to make connections, while others complained about the lack of assistance they said they received from the airline or gate agents. Cirium noted that the vast majority of flights were departing within two hours of their scheduled departure time. A similar percentage — 36% — were arriving at their destinations as scheduled. Dallas-Fort Worth, New York’s Kennedy Airport and Charlotte, North Carolina, saw the greatest number of delays, Cirium said. Washington, Chicago and Miami experienced considerably fewer delays. Meanwhile, the flight-tracking site FlightAware reported that 4,058 flights entering or leaving the U.S., or serving domestic destinations, were delayed, with 76 flights canceled. The site had not posted any American Airlines flights on Tuesday morning, but showed in the afternoon that 961 American flights were delayed. Amid the travel problems, significant rain and snow were expected in the Pacific Northwest at least into Christmas Day. Showers and thunderstorms were developing in the South. Freezing rain was reported in the Mid-Atlantic region near Baltimore and Washington, and snow fell in New York. Because the holiday travel period lasts weeks, airports and airlines typically have smaller peak days than they do during the rush around Thanksgiving, but the grind of one hectic day followed by another takes a toll on flight crews. And any hiccups — a winter storm or a computer outage — can snowball into massive disruptions. That is how Southwest Airlines stranded 2 million travelers in December 2022, and Delta Air Lines suffered a smaller but significant meltdown after a worldwide technology outage in July caused by a faulty software update from cybersecurity company CrowdStrike. Many flights during the holidays are sold out, which makes cancellations even more disruptive than during slower periods. That is especially true for smaller budget airlines that have fewer flights and fewer options for rebooking passengers. Only the largest airlines, including American, Delta and United, have “interline agreements” that let them put stranded customers on another carrier’s flights. This will be the first holiday season since a Transportation Department rule took effect that requires airlines to give customers an automatic cash refund for a canceled or significantly delayed flight. Most air travelers were already eligible for refunds, but they often had to request them. Passengers still can ask to get rebooked, which is often a better option than a refund during peak travel periods. That’s because finding a last-minute flight on another airline tends to be expensive. An American spokesperson said Tuesday was not a peak travel day for the airline — with about 2,000 fewer flights than the busiest days — so the airline had somewhat of a buffer to manage the delays. The groundings happened as millions of travelers were expected to fly over the next 10 days. The Transportation Security Administration expects to screen 40 million passengers through Jan. 2. Airlines expect to have their busiest days on Thursday, Friday and Sunday. Many flights during the holidays are sold out, which makes cancellations more disruptive than during slower periods. Even with just a brief outage, the cancellations have a cascading effect that can take days to clear up. About 90% of Americans traveling far from home over the holidays will be in cars, according to AAA. “Airline travel is just really high right now, but most people do drive to their destinations, and that is true for every holiday,” AAA spokesperson Aixa Diaz said. Gasoline prices are similar to last year. The nationwide average Thursday was $3.04 a gallon, down from $3.13 a year ago, according to AAA. Charging an electric vehicle averages just under 35 cents per per kilowatt hour, but varies by state. Transportation-data firm INRIX says travel times on the nation’s highways could be up to 30% longer than normal over the holidays, with Sunday expected to see the heaviest traffic. Boston, New York City, Seattle and Washington are the metropolitan areas primed for the greatest delays, according to the company. Associated Press writers David Koenig, Mae Anderson and Mike Pesoli contributed to this report.Kilkenny is lighting up this holiday season with the launch of Festive Fridays a Night Time Economy and Shop Kilkenny Initiative . Every Friday of Yulefest, the city will host an array of festive activities designed to bring the community together, support local businesses, and create a vibrant night time atmosphere for both residents and visitors alike. From magical Christmas trails to live entertainment, Festive Fridays at Yulefest Kilkenny promises an unforgettable holiday experience for everyone. Yulefest Christmas Trail: A Journey of Holiday Magic The heart of Festive Fridays lies in the Yulefest Christmas Trail , an experience that invites visitors to explore Kilkenny's historic streets, uncover hidden gems, and participate in an exciting interactive quiz. Christmas Trail Maps are available for collection at the Yulefest HQ (located at the corner of Rose Inn Street and the Parade — Eircode: R95Y672) or local shops. An interactive family friendly trail around Kilkenny city, the trail takes in the city’s Christmas Lights, Christmas Trees and historical areas while ‘reindeer spotting’, answering questions and solving puzzles. A magical way to spend an evening with the family in the beautiful medieval city of Kilkenny this festive season! The trail is a self-guided free activity on public streets. Follow the map to get to every stop and answer the questions and puzzles as you go. Once you’ve completed the trail you can submit your answer sheet in the Yulefest postbox to be in with a chance of winning weekly Shop Kilkenny vouchers! The Yulefest Christmas Trail is live throughout the festival, so you can pick a time that suits you, although we highly recommend the evenings when the lights shine their brightest. A highlight of the trail, as mentioned above, includes: Reindeer Garden at Rothe House Visit this beautiful Kilkenny treasure with a festive twist and come see the Yulefest display of reindeer in the beautiful Rothe House Garden. The garden can be visited from 3pm-6pm throughout December will late opening on Fridays and Saturday till 8pm. Stop in while you’re on the Yulefest Christmas Trail . The retail shop will be open during the garden opening times, selling local crafts and Irish products. An easy place to pick up some gifts while you are here! KCLR Battle of the Buskers This December we’re bringing live entertainment to the streets of Kilkenny! Feel the energy of local talent as Kilkenny's buskers battle it out each week for the chance to win a €500 cash prize, together with recording time in studio and airplay on KCLR 96fm! Featuring a lively blend of musicians performing holiday classics and original tunes, providing the perfect soundtrack to the Christmas festivities. Come out Friday 6th, 13th, 20th December from 6pm, visit all 4 buskers and vote for your favourite! Yulefest Festive Fridays: An Interactive Experience! Launch Celebration: Lights, Music, and Community Spirit The festivities kicked off in grand style on Saturday November 30 with Santa’s arrival to the city and the official launch of Yulefest Kilkenny 2024. Santa took to the River Nore by boat before travelling around Kilkenny’s medieval streets by Steam Train. A spectacular site to behold! Santa and his elves were overwhelmed with the welcome they received at Canal Square and he was delighted to see all of the children and families who came out to see him. Kilkenny’s Mayor Andrew McGuinness had the honor of switching on the city’s Christmas lights alongside Santa himself and Cathaoirleach Michael McCarthy, which filled the streets with a magical glow. The moment was made even more special by a stunning performance from Enya Cox , a talented singer from Castlecomer and finalist on The Voice Kids . Enya's beautiful rendition of ‘Oh, Holy Night’ and ‘Have Yourself a Merry Little Christmas’ provided the perfect soundtrack as the lights illuminated the city, signaling the start of a magical season. Festive Fridays and the Night Time Economy Initiative The Night Time Economy Initiative , in partnership with Shop Kilkenny, is a key part of this year’s Yulefest celebrations, designed to encourage people to experience Kilkenny’s vibrant Christmas scene after dark. By supporting local businesses, the initiative aims to boost the local economy while providing a safe, welcoming, and fun environment for everyone to enjoy the holiday season. Festive Fridays will run from 5 PM to 9 PM, with a host of events, activities, and live performances, ensuring the city remains lively well into the evening. Event Information: When: Every Friday in December, from 5pm to 9pm Where: Kilkenny City Centre Start: Yulefest HQ (Corner of Rose Inn Street and the Parade – Eircode R95Y672) Full Event Details: www.yulefestkilkenny.ie Whether you're here to explore the Christmas trail, enjoy a live performance, or simply soak in the festive atmosphere, Yulefest Kilkenny 2024 offers something for everyone. Don’t miss out on this magical holiday celebration— Kilkenny is waiting to be explored under the stars! Yulefest Kilkenny celebrates Christmas in Kilkenny and runs until December 22. Featuring the Yulefest Christmas Market, live music on the Yulefest Live Music Stage, and family entertainment each weekend plus a range of festive events each week! For more information and the full event schedule, visit www.yulefestkilkenny.ie or follow on social media at @YulefestKilkenny .

Basel, 9 December 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has commenced a tender offer for all of the outstanding shares of common stock of Poseida Therapeutics, Inc. (Poseida) (NASDAQ: PSTX) at a price of $9.00 per share in cash, plus a non-tradeable contingent value right (CVR) to receive certain contingent payments of up to an aggregate of $4.00 per share in cash. The tender offer is being made pursuant to the previously announced merger agreement dated as of November 25, 2024 among Roche Holdings, Inc., an indirect wholly owned subsidiary of Roche Holding Ltd, Blue Giant Acquisition Corp., a wholly owned subsidiary of Roche Holdings, Inc., and Poseida. The tender offer period will expire at one minute following 11:59 p.m., New York City time on 7 January, 2025, unless the offer is extended. Roche has filed a tender offer statement on Schedule TO with the United States Securities and Exchange Commission (SEC). Blue Giant Acquisition Corp. is the acquirer in the tender offer. The Offer to Purchase contained within the Schedule TO sets out the terms and conditions of the tender offer. Poseida has also filed a Solicitation/Recommendation Statement with the SEC on Schedule 14D-9, which includes the unanimous recommendation of the Poseida board of directors that Poseida stockholders tender their shares in the tender offer. Closing of the tender offer is conditioned upon customary closing conditions, including the receipt of required regulatory approvals, and there being validly tendered and not validly withdrawn a majority of the outstanding shares of Poseida common stock. The offer is not subject to any financing condition. Following successful completion of the tender offer, any shares not acquired in the tender offer will be acquired in a second step merger at the same price of $9.00 per share, plus the CVR. The closing of the transaction is expected to take place in the first quarter of 2025. The complete terms and conditions are set out in the Offer to Purchase, which was filed with the SEC today, December 9, 2024. Poseida stockholders may obtain copies of all of the offering documents, including the Offer to Purchase, free of charge at the SEC’s website (www.sec.gov) or by directing a request for the Solicitation/Recommendation Statement on Schedule 14D-9 to Poseida’s website at www.poseida.com or the Offer to Purchase and the other related materials to MacKenzie Partners, Inc., the Information Agent for the offer, toll free at (800) 322-2885 (or please call (212) 929-5500 if you are located outside the U.S. or Canada) or via email at tenderoffer@mackenziepartners.com. Before making any decision with respect to the Offer, investors are urged to read the Offer to Purchase and related documents, as well as the Solicitation/Recommendation Statement, because they contain important information about the Offer. About Poseida Therapeutics Poseida Therapeutics is a clinical-stage biopharmaceutical company advancing differentiated allogeneic cell therapies and genetic medicines with the capacity to cure. The Company’s pipeline includes investigational allogeneic CAR-T cell therapies for hematologic cancers, autoimmune diseases, and solid tumours, as well as investigational in vivo genetic medicines that address patient populations with high unmet medical need. The Company’s approach is based on its proprietary genetic editing platforms, including its non-viral transposon-based DNA delivery system, Cas-CLOVERTM Site-Specific Gene Editing System Booster Molecule and nanoparticle gene delivery technologies, as well as in-house GMP cell therapy manufacturing. The Company has formed strategic collaborations with Roche and Astellas to unlock the promise of cell therapies for cancer patients. About Roche Founded in 1896 in Basel, Switzerland, as one of the first industrial manufacturers of branded medicines, Roche has grown into the world’s largest biotechnology company and the global leader in in-vitro diagnostics. The company pursues scientific excellence to discover and develop medicines and diagnostics for improving and saving the lives of people around the world. We are a pioneer in personalised healthcare and want to further transform how healthcare is delivered to have an even greater impact. To provide the best care for each person we partner with many stakeholders and combine our strengths in Diagnostics and Pharma with data insights from the clinical practice. For over 125 years, sustainability has been an integral part of Roche’s business. As a science-driven company, our greatest contribution to society is developing innovative medicines and diagnostics that help people live healthier lives. Roche is committed to the Science Based Targets initiative and the Sustainable Markets Initiative to achieve net zero by 2045. Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan. For more information, please visit www.roche.com . All trademarks used or mentioned in this release are protected by law. Roche Global Media Relations Phone: +41 61 688 8888 / e-mail: media.relations@roche.com Roche Investor Relations Investor Relations North America Cautionary Statement Regarding Forward-Looking Statements This communication may include statements that are not statements of historical fact, or “forward-looking statements,” within the meaning of the federal securities laws, including with respect to Roche’s proposed acquisition of Poseida. Any express or implied statements that do not relate to historical or current facts or matters are forward-looking statements. These statements are generally identified by words or phrases such as “believe”, “anticipate”, “expect”, “intend”, “plan”, “will”, “may”, “should”, “estimate”, “predict”, “project”, “strategy”, “potential”, “continue” or the negative of such terms or other similar expressions. Such statements include, but are not limited to, the ability of Roche and Poseida to complete the transactions contemplated by the merger agreement, including each party’s ability to satisfy the conditions to the consummation of the offer contemplated thereby and the other conditions set forth in the merger agreement and statements about the expected timetable for completing the transaction. These statements are based upon the current beliefs and expectations of Roche and Poseida’s management and are subject to significant risks and uncertainties. There can be no guarantees that the conditions to the closing of the proposed transaction will be satisfied on the expected timetable if at all. If underlying assumptions prove inaccurate or risks or uncertainties materialize, actual results may differ materially from those set forth in the forward-looking statements, and you should not place undue reliance on these statements. Risks and uncertainties include, but are not limited to, uncertainties as to the timing of the offer and the subsequent merger; uncertainties as to how many of Poseida’s stockholders will tender their shares in the offer; the risk that competing offers or acquisition proposals will be made; the possibility that various conditions to the consummation of the offer and the merger contemplated by the merger agreement may not be satisfied or waived, including that a governmental entity may prohibit, delay or refuse to grant approval for the consummation of the tender offer or the subsequent merger; the ability to obtain necessary regulatory approvals or to obtain them on acceptable terms or within expected timing; the effects of disruption from the transactions contemplated by the merger agreement and the impact of the announcement and pendency of the transactions on Poseida’s business; the possibility that the milestone payments related to the contingent value right will never be achieved and that no milestone payment may be made; and the risk of legal proceedings being brought in relation to the transactions and the outcome of such proceedings, including the risk that stockholder litigation in connection with the offer or the merger may result in significant costs of defense, indemnification and liability. The foregoing factors should be read in conjunction with the risks and cautionary statements discussed or identified in Poseida’s public filings with the SEC, including the “Risk Factors” section of Poseida’s Annual Report on Form 10-K for the year ended December 31, 2023 and subsequent Quarterly Reports on Form 10-Q, Form 8-K and in other filings Poseida makes with the SEC from time to time as well as the tender offer materials to be filed by Roche and its acquisition subsidiary and the Solicitation/Recommendation Statement to be filed by Poseida, in each case as amended by any subsequent filings made with the SEC. Neither Roche nor Poseida undertakes any obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise, except to the extent required by law. Attachment 09122024_Poseida Trade Offer_en

Trump threatened to impose a 25% tax on all products entering the U.S. from Canada and Mexico.

BISMARCK — North Dakota’s new and returning lawmakers met at the state Capitol in Bismarck on Monday, Dec. 2, commencing the three-day organizational session ahead of the lawmaking season. The organizational session is the time during which lawmakers — namely those who are newly elected — familiarize themselves with the procedures and rules necessary to carry out the lawmaking process. It does not count towards the biennial lawmaking session that begins January and lasts up to 80 days. Twenty-two new lawmakers are heading into the 69th legislative session, including two members who returned after not being reelected in recent elections: Sen. Richard Marcellais, D-Belcourt, and Rep. Daniel Johnston, R-Kathryn. Day one included the speaker of the House appointment, committee designations and the swearing-in ceremony. The more menial tasks on the agenda for lawmakers involved computer training, seating arrangement and taking fresh headshots. “Times change, things are different. We have to make sure that everybody’s up to speed,” said House Majority Leader Mike Lefor, R-Dickinson. “You’re going to have your agreements, you’re going to have your disagreements," he said. "But it’s all in the spirit of providing the best public policy that we possibly can.” Both House Republicans and Democrats unanimously agreed on nominating Rep. Robin Weisz to serve as speaker of the House. Weisz described the chamber as “the people’s house” while addressing the Legislature from the podium for the first time as speaker. District 41 newcomer Karen Grindberg, R-Fargo, was also unanimously elected by the district to replace Lt. Gov.-elect Michelle Strinden. “It’s just really exciting how welcoming everybody is and how they want to be helpful,” Grindberg said. Though the intimate details tied to lawmaking are new to the freshman legislator, coming to the Capitol has become second nature. “We used to run around the halls when we were little, that was our favorite thing to do after school," she said. Grindberg’s father was a lawmaker for 22 years and the Republican House Majority Leader. Meanwhile, her husband, Tony Grindberg, was a senator for more than 20 years. She is also the mother of North Dakota Treasurer Thomas Beadle and mother-in-law to Strinden. “I’m excited for the opportunity," Karen Grindberg said. "I want to get to work.” Tuesday’s training will be similar, paying particular attention to ethical topics like workplace harassment and social media conduct. Interim committee findings will also be briefly presented to lawmakers. The session will conclude Wednesday with the presentation and deliberations of Gov. Doug Burgum’s final budget address. Republicans maintain supermajorities in both chambers, outnumbering Democrats 83-11 in the House and 42-5 in the Senate. Neither party will see different leaders for the 2025 session. Lefor and Senate Majority Leader David Hogue, R-Minot, were reelected during Republican caucus meetings last month. Sen. Kathy Hogan, D-Fargo, and Rep. Zac Ista, D-Grand Forks, were reelected as Senate and House minority leaders during the respective state Democratic-NPL caucases.