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CHICAGO (AP) — Aidan Laughery rushed for three touchdowns and No. 22 Illinois topped Northwestern 38-28 on Saturday to reach nine victories for the first time since its 2007 Rose Bowl season. Pat Bryant dashed in to score off Luke Altmyer’s 43-yard pass early in the third quarter as Illinois (9-3, 6-3 Big Ten) struck for touchdowns just over 4 minutes apart early in the third quarter to open a 28-10 lead in what had been a tight game. Bryant's 10th receiving touchdown tied a school record. Altmyer, who threw for 170 yards, had a TD himself on a keeper from the 1-yard line early in the second quarter. David Olano added a field goal in the fourth to cap Illinois' scoring. Laughery, a sophomore running back, rushed for a career-best 172 yards and topped 100 for the first time. He entered with only one TD this season and two for his career. He had a career-long 64-yard run for a score early in the second half. Coach Bret Bielema said he wasn't surprised by Laughery's explosive performance as the Gibson City, Illinois product rounded back into form after being hampered by a hamstring injury earlier this season. “I thought today would be a day that could happen,” Bielema said. “Today some of those turned into big home run hits we've kind of been waiting on all year.” Laughery said he's been prepping for this kind of game, when he carried the ball 12 times for an average of 14.3 yards. “Finally, the opportunity was there,” said Laughery, who got the game ball. “You know you gotta' hit one and it came together today.” He credited the Illini offensive line with opening space for his breakout performance. “Those guys were covering them (Northwestern's defense) all day long,” Laughery said. “It was awesome running behind the looks we were getting” Northwestern’s Devin Turner intercepted Altmyer twice, including for a 13-yard touchdown return late in the first quarter. Thomas Gordon caught Jack Lausch's 15-yard TD pass with a minute left, then the Wildcats added a two-point conversion to complete the scoring. Northwestern (4-8, 2-7 Big Ten) didn’t pack it in as hosted its second game this season at Wrigley Field, this time on a breezy sunny day with game-time temperature of 20 degrees. It looked like the Illini might run away after Bryant’s 10th receiving touchdown 4:52 into the third. He entered tied for the Big Ten lead. But Luke Akers kicked his second field goal of the game, a 34-yarder, with 5:35 left in the third quarter to cut it to 28-13. Lausch led the Wildcats on their next possession and finished it with an 11-yard touchdown toss to A.J. Henning to narrow the Illini lead to 28-20. Then Mac Resetich intercepted Lausch’s pass 50 seconds into the fourth quarter. Laughery powered up the middle for 31 yards and his third TD about two minutes later to quell the Wildcats' momentum. Northwestern dominated in possession time — 34:32 to 25:28 —and plays — 90 to 53. The margin was even more pronounced in the first half, but the Wildcats settled for a 13-yard touchdown return on Turner’s second pick of the game with 2:14 left in the first quarter and Akers’ 21-yard field goal that opened the scoring 6:29 in. Illinois led 14-10 at the half on Laughery’s 30-yard TD run midway through the first quarter and Altmyer’s keeper 1:39 into the second. Akers missed wide to the right on a 44-yard attempt as time ran out in the half. Both teams’ leading pass receivers were injured. Northwestern’s Bryce Kirtz was knocked out of the game in the first quarter with a lower-body injury after two receptions that upped his total yards to 598. Illinois’ Bryant went to the locker room with about 5 minutes left in the first half after Turner collided with him as he plucked his second interception. Bryant returned, however, for the second half. Illinois: Is in line for a prestigious bowl game appearance and a chance to tie the school record of 10 wins, most recently set during their 2001 Sugar Bowl season. “We wanted to put ourselves in a good position on this day to get to nine wins and see where it can go,” Bielema said. “Just a fun day overall. I don't know what the future holds. It think we're a team that can play with anybody in the country.” Northwestern: Finished its second season under coach David Braun at 4-8 overall and 2-7 in the Big Ten. The Wildcats dropped their final three and five of the last six. Illinois is headed to a bowl game. Northwestern opens its 2025 season at Tulane on Aug. 30. AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football . Sign up for the AP’s college football newsletter: https://apnews.com/cfbtop25( MENAFN - ACN NewsWire) Hua medicine Announces Successful H.K. SENSITIZE Study Results at the CBIIC SHANGHAI, Nov 30, 2024 - (ACN Newswire) - Hua Medicine (the“Company”, HKEx stock code: 2552) announced today that the Company has successfully completed its SENSITIZE study on the mechanism by which dorzagliatin improves the β-cell glucose sensitivity at the 9th China BioMed Innovation and investment conference (CBIIC). The SENSITIZE study was initiated by Professor Juliana Chan, an international endocrinology specialist at The Chinese University of Hong Kong, as the lead researcher. It is the first clinical study in Asian populations to evaluate the impact of GKA on β-cell glucose sensitivity in the populations with varying degrees of impaired glucose tolerance using the technology of hyperglycemic clamp. The study aims to explore the impairment of glucokinase (GK) function and clinical characteristics in different types of glucose dysregulation, providing new scientific evidence on the pathophysiology of Asian Type 2 diabetes and the central role of GK in blood glucose regulation. The SENSITIZE 2 study results announced at CBIIC demonstrate that a single dose of dorzagliatin restores GK enzyme activity, significantly improving the second-phase insulin secretion and β-cell glucose sensitivity in individuals with impaired glucose tolerance (IGT) in hyperglycemic clamp study. In addition, the SENSITIZE 1 study previously reported at the 2022 ADA annual meeting showed that dorzagliatin directly restores the activity of GK mutants, leading to significant improvements in the second-phase insulin secretion and β-cell glucose sensitivity in patients with glucokinase monogenic diabetes (GCK-MODY or MODY-2), and significantly enhance basal insulin secretion in newly diagnosed type 2 diabetes patients. Hua Medicine will continue to investigate β-cell glucose sensitivity improvement and incretin effect in response of repeated dose of dorzagliatin in individuals with intermediate hyperglycemia (IH) and Type 2 diabetes, in order to establish personalized intervention and treatment management plans for prediabetic and Type 2 diabetes patients. About Hua Medicine Hua Medicine (The“Company”) is an innovative drug development and commercialization company based in Shanghai, China, with companies in the United States and Hong Kong. Hua Medicine focuses on developing novel therapies for patients with unmet medical needs worldwide. Based on global resources, Hua Medicine teams up with global high-calibre people to develop breakthrough technologies and products, which contribute to innovation in diabetes care. Hua Medicine's cornerstone product HuaTangNing (Dorzagliatin tablets), targets the glucose sensor glucokinase, restores glucose sensitivity in T2D patients, and stabilizes imbalances in blood glucose levels in patients. HuaTangNing was approved by the National Medical Products Administration (NMPA) of China on September 30th, 2022. It can be used alone or in combination with metformin for adult T2D patients. For patients with chronic kidney disease (CKD), no dose adjustment is required. It is an oral hypoglycemic drug that can be used for patients with Type 2 diabetes with renal function impairment. For more information Hua Medicine Website: Investors E-mail: ... Media E-mail: ... 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BJP Faces Factional Challenges in Odisha Amid Modi's VisitMr Bayrou, 73, a crucial partner in Macron’s centrist alliance, has been a well-known figure in French politics for decades. His political experience is seen as key in efforts to restore stability as no single party holds a majority at the National Assembly. Mr Macron’s office said in a statement that Mr Bayrou “has been charged with forming a new government”. During the handover ceremony, Mr Bayrou said that “no one knows the difficulty of the situation better” than he does. “I’ve taken reckless risks all along my political life to raise the issue of debt and deficits in the most important elections,” he said. France is under pressure from the European Union’s executive body and financial markets to reduce its colossal debt, estimated to reach 6% of its gross domestic product this year. “I know that the risks of difficulties are much greater than the chances of success,” Mr Bayrou said, adding that he hopes to lead the country towards a “needed reconciliation”. “I think this is the only possible path to success,” he said. The new prime minister is expected to hold talks with political leaders from various parties in the coming days in order to choose new ministers. Former prime minister Michel Barnier resigned last week following a no-confidence vote prompted by budget disputes in the National Assembly, leaving France without a functioning government. Mr Macron in an address to the nation vowed to remain in office until his term ends in 2027. Mr Macron’s centrist alliance does not have a majority in parliament and Mr Bayrou’s Cabinet will need to rely on moderate lawmakers from the left and the right to be able to stay in power. Some conservatives are expected to be part of the new government. Mr Macron’s strategy aims at preventing far-right leader Marine Le Pen from holding “make or break” power over the government. Ms Le Pen helped oust Mr Barnier by joining her National Rally party’s forces to the left to pass the no-confidence motion last week. Mr Bayrou’s appointment is also in line with Mr Macron’s efforts to build a non-aggression pact with the Socialists so that they commit not to vote against the government in any future confidence motion. Mr Bayrou leads the centrist Democratic Movement, known as MoDem, which he founded in 2007. In 2017, he supported Mr Macron’s first presidential bid and became a weighty partner in the French president’s centrist alliance. At the time, he was appointed justice minister, but he quickly resigned from the government amid an investigation into the MoDem’s alleged embezzlement of European Parliament funds. Mr Bayrou this year was cleared in the case by a Paris court, which found eight other party officials guilty and sentenced the party to pay a fine. Mr Bayrou became well known to the French public when he was education minister from 1993 to 1997 in a conservative government. He was three times a candidate for president: in 2002, 2007 and 2012.LOS ANGELES (AP) — Blake Snell and the Los Angeles Dodgers have finalized a $182 million, five-year contract. The reigning World Series champions announced the deal with the two-time Cy Young Award winner on Saturday. Snell, who turns 32 on Wednesday, went 5-3 with a 3.12 ERA in 20 starts for San Francisco this year, throwing a no-hitter at Cincinnati on Aug. 2 for one of only 16 individual shutouts in the major leagues this season. The left-hander struck out 145 and walked 44 in 104 innings. He was sidelined between April 19 and May 22 by a strained left adductor and between June 2 and July 9 by a strained left groin. Snell gets a $52 million signing bonus , payable on Jan. 20, and annual salaries of $26 million, of which $13 million each year will be deferred. Because Snell is a Washington state resident, the signing bonus will not be subject to California income tax. Snell joins Shohei Ohtani and Yoshinobu Yamamoto atop Los Angeles’ rotation. Ohtani didn’t pitch this year while recovering from right elbow surgery but the two-way star is expected back on the mound in 2025. Snell won Cy Young Awards in 2018 with Tampa Bay and 2023 with San Diego. He is 76-58 with a 3.19 ERA in nine seasons with the Rays (2016-20), Padres (2021-23) and Giants. Because he turned down a qualifying offer from San Diego last November, the Giants were not eligible to give Snell another one and won’t receive draft-pick compensation. AP MLB: https://apnews.com/hub/MLB
Whenever there is oppression, there is resistance, says HRCP chairperson The Home-Based Women Workers Federation (HBWWF) on Sunday organised a seminar on the theme of women’s resistance against oppression at the Karachi Press Club (KPC). The seminar was chaired by Human Rights Commission of Pakistan (HRCP) Chairperson Asad Iqbal Butt and attended by a large number of political and human rights activists. Prominent speakers included Aurat Foundation’s Mahnaz Rahman, Sammi Baloch of the Baloch Yakjehti Council, HBWWF Genera; Secretary Zehra Khan, Sorath Lohar of the Missing Persons Recovery Movement, academic Dr Asghar Ali Dashti, National Trade Union Federation (NTUF) General Secretary Nasir Mansoor and KPC President Saeed Sarbazi. The speakers at the event paid rich tribute to three revolutionary sisters from the Dominican Republic known as the Butterfly Sisters whose struggle against dictatorship is commemorated globally on November 25. Zehra highlighted how the sisters, Patria Mirabal, Minerva Mirabal and Maria Teresa Mirabal, became symbols of democratic freedom and women’s empowerment after they sacrificed their lives in the fight against a brutal regime. The United Nations officially declared November 25 as International Day for the Elimination of Violence Against Women in their honour in 1999. The HBWWF secretary general emphasized that the issues of state oppression, authoritarian governance and misogynistic social attitudes that the Butterfly Sisters fought against persisted globally, including in Pakistan. She said political activists faced persecution in Pakistan, enforced disappearances continued unabated and democratic freedoms were severely restricted. Women workers particularly in factories faced harassment while systemic gender discrimination prevailed in political, social and economic spheres, Zehra lamented. Mansoor said that despite the passage of a law against workplace harassment in Pakistan in 2010, societal norms and judicial delays had made justice nearly unattainable, as a result of which Pakistan remained the sixth most dangerous country for women with alarming statistics. He added that 85 per cent of women workers experienced harassment in workplaces and 90 per cent of domestic workers faced harassment. Forty per cent of women reported digital harassment and 28 per cent of women aged between 14 and 49 years faced physical violence who six per cent were victims of sexual violence. Additionally, over 8,000 families were affected by enforced disappearances with thousands of women enduring psychological and social distress due to missing loved ones, Mansoor said. He recognised the critical role played by women in resisting authoritarianism and advocating for democracy and equality in Pakistan. He highlighted the enduring contributions of figures like Fatima Jinnah, Benazir Bhutto, Asma Jahangir, Kaneez Fatima, Tahira Mazhar Ali and contemporary activists like Dr Mahrang Baloch, Sami Baloch, Sorath Lohar and Zehra Khan. Sharing her personal story, Sammi Baloch of the Baloch Yakjehti Committee brought attention to the plight of families affected by enforced disappearances. Being a woman in this society was itself a form of oppression, she said as she described how Baloch women waited endlessly for their missing loved ones. In his speech, Sarbazi focused on the civil rights issues in the country. He added that the KPC office bearers were committed to protecting the sanctity of the press club and they stood with all the oppressed people. He highlighted how discriminatory policies such as restrictions on hotel stays for people from Balochistan reflected deeper problems. Wherever there was oppression, there was resistance, said the HRCP chairperson. He shared statistics about violence against women and stressed the need for breaking feudal mindset and bringing forward young leadership in the resistance movement. — PPI
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