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Jim Carrey is one of the stars of eagerly awaited sequel Sonic the Hedgehog 3, but the film presents a first in his long Hollywood careeer which might surprise fans. Returning for a double stint in the third chapter of the live-action version based on the iconic video game character, he will reprise his role as Dr. Robotnik and additionally portray the villain's grandfather. This venture represents Carrey's first time doing a second sequel within a franchise. Previously, he has historically dismissed sequels. Prior to Sonic 2's 2022 release, the comedic genius had consented to just two follow-ups during his illustrious tenure. They were Ace Ventura: When Nature Calls back in 1995 and Dumb and Dumber To twenty years after the original. Carrey divulged to GamesRadar, "For me, at this time of my life for some reason I've never really wanted to do sequels. I've never really wanted to do franchise stuff. It didn't occur to me. I just thought, 'I want to move on and do something new'. Maybe six months before the first Sonic movie, I thought to myself I'd like to have a character that I could sit with for a bit for a few films. Especially if it could evolve, if it could change from film to film." "Robotnik has been able to evolve in his look and his manner from film to film. Every time he gets defeated, he becomes more bitter and hostile. His megalomania gets ratched up and these inventions, the technological wonders that he keeps coming up with, keep topping themselves.", reports Wales Online . As Carrey seems to have had a change of heart regarding sequels, anticipation is building among fans for what might come next. The star has set out specific conditions for returning to two of his most beloved characters, The Grinch and Stanley Ipkiss from The Mask. Speaking to Comicbook.com, he said: "Oh gosh, you know, it has to be the right idea. If somebody had the right idea, I guess... It's not really about the money. I joke about the money... But I never know. You can't be definite about these things. I said I'd like to retire, but I think I was talking more about power-resting. Because as soon as a good idea comes your way, or a group of people that you really enjoyed working with and stuff, it just things tend to change." He also outlined his terms for a sequel to The Grinch, noting: "If we can figure out The Grinch... The thing about it is that, on the day, I had to do that with a ton of makeup, and I could hardly breath, and it was an extremely excruciating process. The children were in my mind all the time. 'It's for the kids, it's for the kids, it's for the kids.' And now, with motion capture and things like that, I could be free to do some other things. Anything's possible in this world." Sonic the Hedgehog 3 is in cinemas December 21.TOKYO , Dec. 15, 2024 /PRNewswire/ -- Representatives from China and Japan shared their insights on promoting artificial intelligence (AI) governance and data sharing at a sub-forum of the 20th Beijing-Tokyo Forum in Tokyo recently. The sub-forum contributed eastern wisdom to AI governance and digital social development, demonstrating the significance of international cooperation for the development of the digital economy, according to Gao Shaolin, advisor at Peking University's Legal Artificial Intelligence Research Center. AI governance framework The participants agreed that the next 10 years will be a critical period for the development of AI. Gao Wen, academician of the Chinese Academy of Engineering (CAE), said since China's State Council issued a guideline on developing AI in 2017, the nation has made significant progress in AI research and development and industrial layout, especially in computing power and 5G network construction. By the end of 2023, China had over half of the world's 1.57 billion 5G users, according to the World Internet Development Report 2024. It ranked second globally in AI and computing power scale, which has laid a solid foundation for the rapid development of AI. Tatsuo Yamazaki , project professor at the International University of Health and Welfare, said it was very meaningful for Japan and China to discuss strengthening AI governance rules. Fumihiko Kamio , research director of the Nomura Research Institute, echoed his view. He emphasized that the core goal of AI technology is to improve productivity and eliminate obstacles to social development, and called on Chinese and Japanese experts to work together to build an AI governance framework to cope with the global challenges. Deepening international cooperation China put forth the Global AI Governance Initiative in October last year. In July, the UN General Assembly adopted a China -sponsored resolution on enhancing international cooperation on AI capacity-building. The participants spoke highly of the Global Cross-Border Data Flow Cooperation Initiative recently proposed by China . They agreed that AI governance requires global collaboration, especially in the formulation of international standards and the construction of ethical frameworks, where China and Japan can play an active role. Ding Wenhua, academician of the CAE, said China and Japan have both similarities and differences in technology development and governance priorities, so deepening cooperation will bring unique value to global AI governance. " China and Japan should deepen AI technology cooperation between enterprises, work together in AI security research, talent exchange, and jointly explore more possibilities for the application of technology," Wang Zhongyuan , president of the Beijing Academy of Artificial Intelligence, said. Balancing development & risks AI governance refers to the guardrails established to ensure AI systems and tools remain safe and ethical and respect human rights. Xu Zhilong , editor-in-chief of Science and Technology Daily, stressed that AI, as a revolutionary technology, has far-reaching impacts on all areas of society and economy. However, its potential risks such as data leakage and the spread of false information should not be ignored. "Technological progress and security ethics should be developed in a balanced way to ensure that AI technology always serves the progress of human civilization," Xu said. AI governance should not only heed the current technological ethics issues, but also prevent possible long-term risks, such as AI going out of human control, according to Toshio Iwamoto , senior corporate advisor of NTT DATA. He said AI R&D and application should abide by the principles of fairness, transparency, safety and availability. Yuan Yue, chairman of Beijing Dataway Horizon, shared his view from the perspective of regulatory models. "Policy choices should be based on the current status and goals of national technological development," Yuan said, adding that China prefers to provide a more friendly development environment for enterprises while ensuring an effective response to risks. View original content to download multimedia: https://www.prnewswire.com/news-releases/science-and-technology-daily-promoting-ai-governance-jointly-302332050.html SOURCE Science and Technology DailyYou may have been tempted to believe Donald Trump when he swore, along with some of his Republican colleagues, to protect Social Security. If so, the joke may be on you. That concern emerged Monday when Rep. Mike Lee (R-Utah) uncorked a tweet thread on X labeling Social Security “a classic bait and switch” and “an outdated, mismanaged system.” Twenty-three minutes after Lee posted the first of his tweets, it was retweeted by Elon Musk , who has been vested by Trump with a portfolio to root out inefficiencies in the government. Musk led his retweet with the comment “interesting thread”; if that wasn’t an explicit endorsement, it matched his way of amplifying others’ tweets, tending to give them credibility within the Musk-iverse. Lee’s tweet thread, along with Musk’s apparent concurrence, serves as an outline of the arguments the GOP may use to undermine faith in Social Security, the better to soften it up for “reforms” that will translate into costs imposed on the retirees, disabled workers and their dependents. I recently reported on all the ways that Trump could quietly or secretly undermine his pledge to protect Social Security . Lee’s thread and Musk’s apparent endorsement are different — they amount to a frontal attack on the program. While delving into Lee’s screed, we should keep in mind that he’s a leader of the cabal with the knives out for Social Security. As I’ve reported , during his first successful Senate campaign in 2010, he unapologetically declared, “It will be my objective to phase out Social Security, to pull it out by the roots.” Lee said that was why he was running for the Senate, and added, “Medicare and Medicaid are of the same sort. They need to be pulled up.” So here he is, right out of the box. Lee’s attack has four basic components. One is to bemoan the fact that Social Security is funded mostly by a tax, which he asserts the government can use for any purpose — not necessarily to cover retirement and disability benefits. Another is to point out that the program’s reserves aren’t stored in individual accounts with workers’ names on them, but collected in “a huge account called the ‘Social Security Trust Fund.’” A third is to claim that “the government routinely raids this fund ... They take ‘your money’” and use it for whatever the current Congress deems ‘necessary.’” And a fourth is to complain that the trust fund is mismanaged: “If you had put the same amount into literally ANYTHING else—a mutual fund, real estate, even a savings account—you’d be better off by the time you reached retirement age, even if the government kept some of it!” He states: “Your ‘investment’ in Social Security can give you a return lower than inflation.” None of these is a new argument — they’ve been swirling around the conservative and Republican fever swamp like a miasma for decades. They’ve been consistently refuted and debunked. Lee can’t be unaware of that. Some of his arguments have a tiny nugget of truth at their center, but in his hands are twisted and manipulated out of recognition. Consequently, we can label his claims for what they are: Lies. Let’s examine them one by one. (I asked Lee via a message at his office to justify his tweets , but haven’t heard back.) Yes, Social Security is funded by taxes. So what? Lee’s salary as a senator is funded by taxes, too. Does that make it illegitimate? It’s true that once a tax is collected Congress can decided to spend it however it wishes. But it’s also true that the payroll tax was enacted jointly with the provisions of the Social Security Act that designated the revenue for Social Security benefits. As Supreme Court Justice Benjamin Cardozo observed in 1937, writing for the majority in a 7-2 opinion upholding the constitutionality of Social Security , it was clear that Congress intended the payroll tax to fund the benefits, for lawmakers “would have been unwilling to pass one without the other.” It’s proper to note here that no one has ever proposed diverting Social Security revenues for any other purpose without recompense — except Republicans such as Lee. George W. Bush proposed converting Social Security into private accounts, which would have been tantamount to such a diversion — and a gift to Wall Street money managers eager to get their hands on the program’s trillions of dollars. But Bush’s 2005 privatization plan was stillborn and he quickly abandoned it. It’s also true that the program’s revenues aren’t stored in individual accounts but in the trust fund. That’s right and proper: Social Security is a shared benefit; no one can know in advance what any worker’s benefits will be. They’re pegged to career earnings, but low-income workers get higher benefits relative to wages than higher-income workers. They’re also related to a worker’s personal and family situation — spouses, dependents, health and so on. It also makes sense to invest the program’s revenues in a shared account, because large investments tend to perform better over time than those under the control of individuals, not least because that minimizes transaction costs. That brings us to the notion that the government “routinely raids” the trust funds (there are two, actually — one to cover old-age benefits and the other to cover disability payments — but they’re generally treated as a single combined fund). The trust funds currently hold about $2.8 trillion in assets, all invested in U.S. Treasury securities. Holding a T-bond, as anyone with a slightest knowledge of government fiscal policy is aware, means the bondholder has lent the money to the government, which can use it for any purpose Congress chooses and which must pay interest on the bond. Over the years, the government has used the money to build roads and other infrastructure and provide services. Using the borrowed money for these purposes allows the government to do so without raising income taxes, which would hit the wealthy harder than middle- or low-income Americans. Lee should ask his well-heeled patrons if they’d prefer to pay higher taxes because the government couldn’t borrow from the Social Security reserves. Anyone have any doubts about how they’d answer? Me neither. In any event, the financial transactions related to the buying and redemption of the program’s treasury holdings are fully disclosed every year by the program trustees in their annual report . What about Lee’s assertion that investing in “ANYTHING else—a mutual fund, real estate, even a savings account,” would make you “better off by the time you reached retirement age.” This statement is as solid a compendium of financial ignorance as one might wish, even coming from a U.S. Senator. To begin with, if Lee thinks the Social Security trust fund should be invested in something other than treasuries, he can take that up with his colleagues on Capitol Hill. They’re the ones who have mandated, by law, that the trust fund can be invested only in treasuries. Over the years, proposals to widen the portfolio have been raised and abandoned, for several reasons. Some were concerned about the potential conflicts of interest inherent in a government program investing in the stock market; others that the returns from market investments are too volatile. Savings accounts? Is Lee kidding? The rate on savings accounts offered to the average customer of Bank of America, to choose a commercial bank at random, is 0.01% a year. As I write, a 10-year treasury bond yields about 4.2% annually. As for Lee’s assertion that “Social Security can give you a return lower than inflation,” the fact is that Social Security benefits are adjusted for inflation every year. They’re also lifetime benefits. Try to find an annuity plan that pays inflation-adjusted benefits for the life of the annuity holder and his or her spouse — for all but the richest people, it would be unaffordable or at least uneconomical. Lee also reveals a fundamental misunderstanding about Social Security as a program. It’s not just a retirement program, but a combined retirement and insurance program. Disabled workers — and their dependents — are entitled to benefits well beyond their contributions; the families of workers who die before retirement age receive benefits that include payments to children through age 17 — through age 18 if they’re in school. If those benefits were based on the balances in a worker’s individual account, then the families of those who have suffered untimely deaths could amount to a pittance, running out while still needing help. Lee concludes by urging his followers to “acknowledge the truth: Social Security as it now exists isn’t a retirement plan; it’s a tax plan with retirement benefits as an afterthought.” This is an outright falsehood. As it now exists, Social Security isn’t just a retirement plan, but a disability program. It’s funded by taxes, but to call retirement benefits “an afterthought” is so wrong it’s frightening. What should be think about all this? Lee is a member of the Senate majority; his proposals could be a real threat to the program. The fact that they garnered an “attaboy” from Elon Musk should be their death knell. Let’s hope so.Unwrap the latest AI features with Amazon Fire Tablets
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Prince Andrew ‘ceased all contact’ with man accused of being a Chinese spy after concerns raisedThe controversy around a religious Christmas sign that was taken down in downtown Kelowna continues. Two days after a sign stating 'Keep Christ in Christmas' was removed from the nativity scene display at Stuart Park, Kelowna-Centre MLA Kristina Loewen went to social media to express her opinion on the matter. "We believe that it's an important detail that Christmas is a Christian holiday," said Loewen in her video, referring to 'we' as all of the MLAs for the Central Okanagan. "We will be standing united and defending all British Columbians rights to religion and freedom of expression, speech, thought, belief," she added. "Canada is an incredible country full of diverse cultures and religions, and a wide variety of views, and I think that's one of the things that makes us so incredible." Kelowna-Lake Country-Coldstream MLA Tara Armstrong agreed with her fellow Conservative, quote-tweeting the video and saying "a great message from a colleague and friend. I'm proud to be part of a team that stands for what's right." Macklin McCall, MLA for West Kelowna, also quote-tweeted Loewen's post. However, Kelowna-Mission MLA Gavin Dew appears to not have commented on social media. The nativity scene is put up by the Knights of Columbus every year and a permit is given from the City of Kelowna to do so. When the 'Keep Christ in Christmas' sign was displayed beside the scene on Monday, Dec. 9, some people in the community, including the Kelowna Atheists, Skeptics, and Humanists Association (KASHA) took issue. A letter by KASHA to Black Press Media on Dec. 9, stated the nativity scene is part of Christmas, just as "lights, festive trees, and other decorative displays" are also. "This message is not merely festive—it is political, advocating for a specific religious interpretation of the holiday," said KASHA about the sign. The next day, the sign was taken down and the City of Kelowna confirmed that the sign was not part of the Knights of Columbus' permit for the nativity scene. The Knights of Columbus had no comment regarding the matter. Capital News reached out to Loewen for further comment but was met with an automatic e-mail reply. Additionally, the City of Kelowna stated it had no comment on Loewen's video. However, Ian Bushfield the executive director of the B.C. Humanist Association did have a comment. "Freedom of religion in Canada includes freedom from religion," said Bushfield in an e-mailed statement. "Ms. Loewen and all Christians are obviously free to celebrate Christmas as a Christian holiday but our governments have a clear duty of religious neutrality. That means neither endorsing nor prohibiting any religion over any other. That sign, and arguably even the nativity scene, being on public property breaches that duty. She can put the sign up at her church or at her own house but we do not live in a theocracy." Bushfield has previously stated that BCHA is an organization committed to secular values. “Part of that is the separation of religion and government," said Bushfield. The City of Kelowna also said it received five letters on the matter when the sign was up but none since it's been taken down.
Published 5:27 pm Friday, November 22, 2024 By Minnesota Public Radio By Matt Sepic, Minnesota Public Radio News Two prospective marijuana business owners who were barred from participating in a license lottery are suing Minnesota cannabis regulators. The Office of Cannabis Management announced Friday that it will hold a drawing on Tuesday to determine who will operate the state’s first legal marijuana businesses. The OCM turned to a lottery because more than 1,800 applicants had sought 282 licenses. The first to apply are those considered social equity applicants under the law. They include people who live in high poverty areas, those harmed by the war on drugs, and military veterans. This week, regulators disqualified two-thirds of the applicants for a variety of reasons. In a lawsuit, Jodi Connolly alleges that OCM gave no reason for denying her application. Connolly’s co-plaintiff Cristina Aranguiz said she received only a cursory explanation. The two call the rejections “arbitrary and capricious,” and they want a judge to stop the lottery while their lawsuit is pending. A judge set a restraining order hearing for Monday at 9 a.m. In an email to MPR News on Friday, a spokesperson for the Office of Cannabis Management said he cannot comment on the litigation, but OCM still plans to move ahead with the scheduled lottery.Enlicitide decanoate is a peptide commercialized by , with a leading Phase III program in Hypercholesterolemia. According to Globaldata, it is involved in 22 clinical trials, of which 12 were completed, 9 are ongoing, and 1 is planned. Smarter leaders trust GlobalData The gold standard of business intelligence. The revenue for Enlicitide decanoate is expected to reach an annual total of $244 mn by 2037 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress. Enlicitide decanoate Overview Enlicitide decanoate (MK-0616) is under development for the treatment of atherosclerotic cardiovascular disease (ASCVD), hypercholesterolemia and heterozygous familial hypercholesterolemia (heFH). It is administered through oral route in the form of tablet or capsule. The drug candidate acts by targeting proprotein convertase subtilisin/kexin type 9 (PCSK9). Merck Overview is a biopharmaceutical company with focus on the discovery, development, manufacturing and marketing of prescription medicines, biologic therapies, vaccines, and animal health products. It offers prescription products for the treatment of cardiovascular conditions, cancer, immune disorders, infectious and respiratory diseases, and diabetes, among others. The company provides animal health products such as vaccines, poultry products, livestock products and aquaculture products. sells medicines to drug wholesalers, retailers, hospitals, government agencies and managed health care providers; and animal health products to veterinarians, distributors, and animal producers. The company and its subsidiaries operate in the Americas, Europe, the Middle East, Africa, Asia Pacific, and Latin America. is headquartered in Rahway, New Jersey, the US. The company reported revenues of (US Dollars) US$60,115 million for the fiscal year ended December 2023 (FY2023), an increase of 1.4% over FY2022. In FY2023, the company’s operating margin was 3%, compared to an operating margin of 30.3% in FY2022. In FY2023, the company recorded a net margin of 0.6%, compared to a net margin of 24.5% in FY2022. The company reported revenues of US$16,112 million for the second quarter ended June 2024, an increase of 2.1% over the previous quarter. For a complete picture of Enlicitide decanoate’s valuation, From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company. The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s .
Ruud van Nistelrooy savoured his first match in charge of Leicester with a 3-1 Premier League win over West Ham, while Crystal Palace edged Ipswich 1-0 on Tuesday. Get all the latest football news, highlights and analysis delivered straight to your inbox with Fox Sports Sportmail. Sign up now!!! Jamie Vardy, Bilal El Khannouss and Patson Daka got the goals as Van Nistelrooy enjoyed a dream start to his new role shortly after his departure from Manchester United. “On a long-term basis we know the performances need to get better. But the spirit and how we want to do things we saw today because, if not, the Premier League is too brutal,” said Van Nistelrooy. The Dutchman said he had been “astonished” by the number of offers he received after a four-game spell as interim United boss, which included two wins over Leicester. A lethal finisher in his playing days, Van Nistelrooy watched on approvingly as Vardy opened the scoring after just 99 seconds at the King Power. The 37-year-old had initially been flagged offside, but a VAR review showed he was clearly on for his fifth goal of the season. Defeat ramps up the scrutiny of Hammers boss Julen Lopetegui after a seventh defeat in 14 Premier League games. The visitors enjoyed the majority of possession and had 31 shots to Leicester’s eight but failed to make it count. “A frustrating night because we deserved much more today,” said Lopetegui. “Normally we have to win this match but we didn’t because we didn’t score.” West Ham did have a goal controversially ruled out when Leicester goalkeeper Mads Hermansen punched the ball into his own net and was relieved to be awarded a foul due to minimal contact from Tomas Soucek. Conor Coady also cleared off the line from Crysencio Summerville in the second half. But Leicester remained a threat on the counter-attack and doubled their lead when El Khannouss coolly stroked home Kasey McAteer’s pass. Daka then blasted in to make it 3-0 before Niclas Fuellkrug netted a late consolation with his first West Ham goal. Victory lifts Leicester up to 15th, four points above the relegation zone, and within two points of 14th-placed West Ham. - Guehi defies FA - Jean-Philippe Mateta scored the only goal at Portman Road as Palace won the battle of two more sides at the bottom end of the table. The Frenchman produced a classy finish from Eberechi Eze’s pass on the hour mark to secure the Eagles’ first away win of the season. Palace pull three points clear of the bottom three, while Ipswich remain second from bottom and winless at home on their return to the top flight. However, Palace captain Marc Guehi is now at risk of a suspension after defying a Football Association warning over displaying religious messages. As part of the “Rainbow Laces” campaign to show support for the LGBTQ+ community, Premier League captains are wearing rainbow-coloured armbands. Guehi’s armband bore the message “I love Jesus” during their 1-1 draw against Newcastle, prompting the FA to contact Guehi and Palace and remind them of rules forbidding the display of religious messages. The England defender doubled down on his message with “Jesus loves you” displayed on his rainbow-coloured armband. “Everyone now is about integration, no discrimination and Marc as well,” said Palace boss Oliver Glasner. “He has his opinion and we accept and respect every opinion.” Ipswich captain Sam Morsy, who also caused controversy by opting not to wear the rainbow armband against Nottingham Forest at the weekend, once again wore a regular armband. His club issued a statement on Monday saying he chose not to wear the rainbow armband due to his religious beliefs.
